Results 81 to 90 of about 35,609 (207)

Structure of the haptoglobin-haemoglobin complex [PDF]

, 2012
Red cell haemoglobin is the fundamental oxygen-transporting molecule in blood, but also a potentially tissue-damaging compound owing to its highly reactive haem groups.
Andersen, Christian Brix Folsted, Oliveira, Cristiano Luis Pinto de, Hersleth, Hans-Petter, Andersen, Gregers Rom, Nielsen, Marianne Jensby, Andersen, Niels Hojmark, Torvund-Jensen, Morten, Pedersen, Jan Skov, Moestrup, Soren Kragh   +8 more
core   +1 more source

Validity of hypertensive disorders of pregnancy diagnoses in the Swedish pregnancy register using a contemporary cohort

Acta Obstetricia et Gynecologica Scandinavica, EarlyView.
In this contemporary Swedish cohort, a diagnosis of preeclampsia recorded in the Swedish Pregnancy Register demonstrated good validity, comparable to that reported in previous Nordic register validation studies. Abstract Introduction The validity of hypertensive disorders of pregnancy (HDP), including preeclampsia, gestational hypertension, and chronic
Mark Frick, Lina Bergman, Ylva Carlsson, Henrik Imberg, Peter Lindgren, Peter Conner, Stefan R. Hansson, Marius Kublickas, Anders Larsson, Sara Hellström, Anna‐Karin Wikström, Anna Sandström   +11 more
wiley   +1 more source

Haptoglobin genotypes, inflammation status and their associations with hemoglobin levels in stage 4 chronic kidney disease patients with anemia [PDF]

Background and aims: Anemia and increased inflammation are the main causes of mortality in chronic kidney disease (CKD) patients. This study was designed to explore the probable relationship of hemoglobin (Hb) with serum haptoglobin (HP), its ...
ارگانی, حسن, حسینی اصل, سید سعید, علی پناه مقدم, رضا, قربانی حق جو, امیر   +3 more
core  

Studies on Serum Haptoglobin On Changes of Serum Haptoglobin Levels in Liver Injury and Effects of Vitamins C and K1 upon Serum Haptoglobin Levels. [PDF]

, 1968
Effect of liver dysfunction upon the serum haptoglobin level was studied both clinically and experimen-tally. Effects of vitamin C and vitamin K1 upon serum haptoglobin levels were also studied.
森田, 益幸
core   +2 more sources

Thrombocytosis and the generation of platelet‐derived microparticles in the pathophysiology of sickle cell disease

British Journal of Haematology, EarlyView.
Thrombocytosis is associated with an increased production of platelet‐derived microparticles from activated platelets, which contribute to vaso‐occlusion in sickle cell disease by perpetuating the cycle of inflammation, procoagulant state and endothelial dysfunction.
Giao N. Lê, Anna Dillon, Owen P. Smith, Corrina McMahon   +3 more
wiley   +1 more source

Diagnostic accuracy of intraoperative haptoglobin point-of-care testing in ovarian tumor fluid versus frozen section for epithelial ovarian cancer

BMC Research Notes
Objective Ovarian cancer is the third most common gynaecological cancer and has the high mortality rates and requires accurate intraoperative. Haptoglobin is an acute-phase protein locally elevated in cancer cells, may serve as a novel diagnostic marker.
Benyamin Rakhmatsyah Titaley, Siti Salima, Andi Kurniadi, Dodi Suardi, Ali Budi Harsono, Gatot Nyarumenteng Adhipurnawan Winarno, Patiyus Agustiansyah, Aisyah Shofiatun Nisa   +7 more
doaj   +1 more source

Haptoglobin is dispensable for haemoglobin uptake by Trypanosoma brucei

Frontiers in Immunology
Haptoglobin is a plasma protein of mammals that plays a crucial role in vascular homeostasis by binding free haemoglobin released from ruptured red blood cells.
Eva Horáková, Eva Horáková, Marek Vrbacký, Martina Tesařová, Eva Stříbrná, Jan Pilný, Zuzana Vavrušková, Marie Vancová, Marie Vancová, Roman Sobotka, Roman Sobotka, Julius Lukeš, Julius Lukeš, Jan Perner   +13 more
doaj   +1 more source

GLUT1 Deficiency Syndrome with Coexistent Movement Disorder and Anemia

Movement Disorders Clinical Practice, EarlyView.
Sangeetha Yoganathan, Haya S AlFaris, Anika Menetrey, Sayoni Roy Chowdhury, Lindsey Vogt, Jolynn Dickson, Karen Owusu, Pradeep Krishnan, Suvasini Sharma, Liali Aljouda, Reena Pabari, Grace Yoon, Carolina Gorodetsky   +12 more
wiley   +1 more source

Pegcetacoplan Delivers Real‐World Therapeutic Benefits and Reduces Disease Burden for Patients With Paroxysmal Nocturnal Haemoglobinuria: A Systematic Literature Review of Pegcetacoplan Real‐World Clinical and Patient‐Reported Outcomes

European Journal of Haematology, EarlyView.
ABSTRACT Aims Paroxysmal nocturnal haemoglobinuria (PNH) is an ultra‐rare, acquired, non‐malignant haematological disorder that, if left untreated, can lead to significant morbidity. This systematic literature review (SLR) summarized real‐world evidence (RWE) for pegcetacoplan, a complement 3/3b inhibitor (C3i) available since 2021.
Juan Carlos Vallejo Llamas, Koo Wilson, Zalmai Hakimi, Vikte Lionikaite, Elisabetta Metafuni   +4 more
wiley   +1 more source

Haptoglobin modifies the hemochromatosis phenotype in mice [PDF]

, 2005
Classic hereditary hemochromatosis (HH) is a common genetic disorder of iron metabolism caused by a mutation in the HFE gene. Whereas the prevalence of the mutation is very high, the clinical penetrance of the disease is low, suggesting that the HFE ...
GARUTI, Cinzia, N. C. Andrews, PIETRANGELO, Antonello, E. Tolosano, L. Valli, F. Altruda, S. Fagoonee   +6 more
core   +1 more source