Results 31 to 40 of about 84,533 (300)

Toward a better understanding of tool wear effect through a comparison between experiments and SPH numerical modelling of machining hard materials [PDF]

open access: yes, 2009
The aim of this study is to improve the general understanding of tungsten carbide (WC–Co) tool wear under dry machining of the hard-to-cut titanium alloy Ti6Al4V. The chosen approach includes experimental and numerical tests.
Salaün, Michel   +17 more
core   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Lyapunov Modes in Hard-Disk Systems [PDF]

open access: yes, 2018
We consider simulations of a two-dimensional gas of hard disks in a rectangular container and study the Lyapunov spectrum near the vanishing Lyapunov exponents. To this spectrum are associated "eigen-directions”, called Lyapunov modes.
Posch, Harald   +3 more
core  

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Collective Dynamics in Quasi-One-Dimensional Hard Disk System

open access: yesFrontiers in Physics, 2021
We present the results of molecular dynamic studies of collective dynamics in a system of hard disks confined to a narrow quasi-one-dimensional (quasi-1D) channel. The computer simulations have been performed for the specific channel width of 3/2 of disk
Adrián Huerta   +4 more
doaj   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

open access: yesFEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto   +3 more
wiley   +1 more source

A Competing Risk Model of Reliability Analysis for NAND-Based SSDs in Space Application

open access: yesIEEE Access, 2019
This paper develops a competing risk model to simultaneously analyze censored catastrophic failures and nonlinear degradation data of the NAND-based solid-state drives for space application.
Peng Li   +4 more
doaj   +1 more source

Analysis of vibration and sound characteristics of fluid conveying pipeline considering the effect of acoustic-solid coupling

open access: yesZhongguo Jianchuan Yanjiu, 2021
ObjectivesIn order to accurately grasp the vibration and sound characteristics of pipelines, a numerical simulation is carried out.Methods Based on the theory of acoustic-solid coupling, a numerical model of a pipeline is established.
Dejin CHEN   +4 more
doaj   +1 more source

The human gut microbiome across the life course

open access: yesFEBS Letters, EarlyView.
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero   +4 more
wiley   +1 more source

The heart of political steering: the EU's areana of power as template for a governance typology [PDF]

open access: yes, 2009
The literature on the so-called new modes of governance in the European Union focuses on steering instruments beyond hierarchy and coercion. While it has repeatedly been put into question how ‘new’ these instruments are, no systematic attention has ...
Heidbreder, Eva G.
core  

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