Results 41 to 50 of about 84,533 (300)
, 2018 Accurately predicting protein-ligand binding is a major goal in computational chemistry, but even the prediction of ligand binding modes in proteins poses major challenges. Here, we focus on solving the binding mode prediction problem for rigid fragments.
John D., Chodera +7 more
core +1 more source
Short-wavelength collective modes in a binary hard-sphere mixture [PDF]
Physical Review A, 1990 We use hard-sphere generalized hydrodynamic equations to discuss the extended hydrodynamic modes of a binary mixture. The theory presented here is analytic and it provides us with a simple description of the collective excitations of a dense binary mixture at molecular length scales.
Marchetti, M. +3 more
openaire +3 more sources
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Journal of Materials Research and TechnologyJointed soft-hard composite rock mass is very common in engineering. The existence of joint and the uncoordinated deformation of soft-hard layer make the failure behavior more complicated.
Hang Lin, Su Li, Xing Zhang
doaj +1 more source
Experimental observations of an 8ms-1 drop test of a metallic helicopter underfloor structure onto a hard surface: part 1 [PDF]
, 2007 : This is the first part of a two-part paper that describes the experimental observations for two similar sections of floor that were dropped onto both hard and water surfaces at 8 m/s, as a part of one experimental campaign.
Hughes, Kevin +2 more
core
FEBS Letters, EarlyView.The pyruvate generator, which causes activation of respiration by extra‐mitochondrial Ca2+, is also present and functional in rat brainstem mitochondria, as it is in other brain regions. This finding is confirmed by experiments with a fully reconstituted malate–aspartate shuttle (MAS).
Grazyna Debska‐Vielhaber +7 more
wiley +1 more source
Acta Metallurgica Slovaca, 2016 We consider the study results of the hard-to-process titanium-based alloys processing on turning lathes. The influence made on the quality of the surface layer, characterized by the amplitude roughness parameters, by geometry, cutting tool properties ...
Eduard Leonidovich Zhukov +2 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Hybrid Damping Mode MR Damper: Development and Experimental Validation with Semi-Active Control
MachinesThis study introduces a novel magnetorheological (MR) damper for semi-active vehicle suspension systems that enhance ride comfort and handling stability.
Jeongwoo Lee, Kwangseok Oh
doaj +1 more source
Softest elastic mode governs materials hardness
Chinese Science Bulletin, 2014 Single-crystal elastic constants and mechanical hardness of covalent and ionic crystals have been studied using first-principles calculations. The results show that the hardness is dominated by the softest elastic mode, not by the averaged elastic moduli as generally assumed.
Rong Yu, Qi Zhang, Qian Zhan
openaire +1 more source