Results 61 to 70 of about 1,935,322 (253)
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
Trapped modes in a waveguide with a long obstacle [PDF]
, 2000 Consider an infinite two-dimensional acoustic waveguide containing a long rectangular obstacle placed symmetrically with respect to the centreline. We search for trapped modes, i.e.
Parnovski, L, Khallaf, NSA, Vassiliev, D
core
Thermodynamics and vibrational modes of hard sphere colloidal systems [PDF]
, 2014 The central question that we address in this thesis is the thermodynamics of colloidal glasses. The thermodynamics of colloidal hard sphere glasses are directly related to the entropy of the system, since the phase behavior of hard sphere systems is ...
Zargar, R.
core +5 more sources
A More Reasonable Definition of Failure Mode for Mechanical Systems Using Meta-Action
IEEE Access, 2019 Identification of failure modes is a vital work in the process of failure mode and effect analysis (FMEA). Since the traditional failure mode is defined as a specific function failure or a part failure, there are uncountable failure modes for mechanical ...
Hui Yu, Genbao Zhang, Yan Ran
doaj +1 more source
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Modes and resemiotisation of HIV and aids messages in the eastern region of Malawi [PDF]
, 2013 Philosophiae Doctor - PhDThis study explores how HIV and AIDS discourse is differently constituted and evaluated across different modes by different communities of speakers in Malawi.
Kunkeyani, Thokozani Eunice
core +1 more source
Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
wiley +1 more source
Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding
FEBS Letters, EarlyView.In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança +2 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Eurasian Physical Technical JournalThis article examines several aspects of the electrohydraulic drilling method. It presents the results of an experimental study examining the influence of electrohydraulic drilling modes on the efficiency of breaking stone.
K.M. Shaimerdenova +5 more
doaj +1 more source