Results 121 to 130 of about 615,704 (332)
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Intense 2-cycle laser pulses induce time-dependent bond-hardening in a polyatomic molecule
, 2012 A time-dependent bond-hardening process is discovered in a polyatomic molecule (tetramethyl silane, TMS) using few-cycle pulses of intense 800 nm light.
Dharmadhikari, A. K. +5 more
core +1 more source
FEBS Letters, EarlyView.Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson +7 more
wiley +1 more source
UNSTRAIN TEMPERING TECHNOLOGY IN MAGNET SPACE OF THIN-WALLED RING ITEMS
Advanced Engineering Research, 2011 The availability of the external magnetic field for the simultaneous embodiment of hardening reserves and strain elimination of thin-walled ring items at the expense of the magnetic field initiating effect on the martensitic transformation within the ...
Victor N. Pustovoit, Yuri V. Dolgachev
doaj
FEBS Letters, EarlyView.We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee +3 more
wiley +1 more source
SOFTENING OF HARDENED MEDIUM-CARBON STEEL DURING HEATING
Nauka ta progres transportu, 2019 Purpose. The work is aimed to clarify the softening mechanism during the heating of martensite hardened carbon steel, which is of practical importance, especially in the development of the production technology of rolled products with different levels of
I. O. Vakulenko +3 more
doaj +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Acclimatization of in Vitro-derived Dendrobium
Horticultural Plant Journal, 2017 The successful ex vitro establishment of Dendrobium plantlets raised in vitro determines the quality of the end product (cut flowers or potted plants) in commercial production for economic gain.
Jaime A. Teixeira da Silva +5 more
doaj +1 more source
Spectral Hardening of Large Solar Flares
, 2008 RHESSI observations are used to quantitatively study the hard X-ray evolution in 5 large solar flares selected for spectral hardening in the course of the event.
A. O. Benz, Massaro E., P. C. Grigis
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source