Results 121 to 130 of about 417,880 (332)
Cattleya trianae is an endemic species from the tropical rainforest in the Colombian Andes. Its survival is currently threatened due to habitat loss and commercial overexploitation.
Marcela Franco +3 more
doaj
Texture evolution of "Amaretti" cookies during storage [PDF]
The results of a study on texture evolution during 35 days of storage of ldquoamarettirdquo, a typical Italian cookie, packaged in two different ways are reported.
Catzeddu, Pasquale +3 more
core
Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son +13 more
wiley +1 more source
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
ABOUT HEAT TREATMENTS APPLIED TO FERROUS ALLOYS AND METALS [PDF]
Materials and non-ferrous alloys lends itself through more plastic deformation processes. It is known that after deformation the material structure, as well as properties that are no longer adequate therefore is applied recrystallization annealing for ...
Alin Stancioiu
doaj
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Penelitian ini bertujuan untuk menganalisis struktur mikro baja ST 60 setelah perlakuan pengerasan (hardening) dengan menggunakan variasi media pendingin.
Dewi Izzatus Tsamroh +2 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Fegra fig (Ficus palmata) is an important fruit-yielding crop and potential rootstock for grafting Ficus carica. The acclimatization phase is a pivotal step during the micropropagation of plants.
Y. H. Dewir +7 more
doaj +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source

