Results 91 to 100 of about 884,654 (363)

Assessment of Knowledge, Attitude and Practice Regarding Single Use Plastics among the Residents of a Rural Area in a Coastal District of Karnataka - A Descriptive Study

open access: yesNational Journal of Community Medicine, 2020
Background: The consumption of single-use-plastics is on the rise globally. This study was conducted to assess the knowledge, attitude and practice on single-use-plastics among the residents of a rural area in a coastal district of Karnataka. Methods:
Habeena Shaira   +7 more
doaj   +1 more source

Harm reduction principles for healthcare settings

open access: yesHarm Reduction Journal, 2017
BackgroundHarm reduction refers to interventions aimed at reducing the negative effects of health behaviors without necessarily extinguishing the problematic health behaviors completely.
Mary E Hawk   +6 more
semanticscholar   +1 more source

Neutrophil deficiency increases T cell numbers at the site of tissue injury in mice

open access: yesFEBS Letters, EarlyView.
In wild‐type mice, injury or acute inflammation induces neutrophil influx followed by macrophage accumulation. Mcl1ΔMyelo (neutrophil‐deficient) mice lack neutrophils, and in response to muscle injury show fewer macrophages and exhibit strikingly elevated T‐cell numbers, primarily non‐conventional “double‐negative” (DN) αβ and γδ T cells.
Hajnalka Halász   +6 more
wiley   +1 more source

Do No Harm [PDF]

open access: yesAMA Journal of Ethics, 2018
After a goals-of-care conversation, this patient's chart listed his status as "full-code." As shown in this image, resuscitation was initiated for a 92-year-old man with metastatic malignancy after being found pulseless by the rounding team.
openaire   +2 more sources

Beyond Sacrificial Harm: A Two-Dimensional Model of Utilitarian Psychology

open access: yesPsychology Review, 2017
Recent research has relied on trolley-type sacrificial moral dilemmas to study utilitarian versus nonutilitarian modes of moral decision-making. This research has generated important insights into people’s attitudes toward instrumental harm—that is, the ...
G. Kahane   +6 more
semanticscholar   +1 more source

Exploring lipid diversity and minimalism to define membrane requirements for synthetic cells

open access: yesFEBS Letters, EarlyView.
Designing the lipid membrane of synthetic cells is a complex task, in which its various roles (among them solute transport, membrane protein support, and self‐replication) should all be integrated. In this review, we report the latest top‐down and bottom‐up advances and discuss compatibility and complexity issues of current engineering approaches ...
Sergiy Gan   +2 more
wiley   +1 more source

Ergothioneine supplementation improves pup phenotype and survival in a murine model of spinal muscular atrophy

open access: yesFEBS Letters, EarlyView.
Spinal muscular atrophy (SMA) is a genetic disease affecting motor neurons. Individuals with SMA experience mitochondrial dysfunction and oxidative stress. The aim of the study was to investigate the effect of an antioxidant and neuroprotective substance, ergothioneine (ERGO), on an SMNΔ7 mouse model of SMA.
Francesca Cadile   +8 more
wiley   +1 more source

Do No Harm: Health Systems’ Duty to Promote Clinician Well-Being

open access: yesAmerican Journal of Hospital Medicine, 2022
Anish K. Agarwal, Thea Gallagher
semanticscholar   +1 more source

Microbial exopolysaccharide production by polyextremophiles in the adaptation to multiple extremes

open access: yesFEBS Letters, EarlyView.
Polyextremophiles are microorganisms that endure multiple extreme conditions by various adaptation strategies that also include the production of exopolysaccharides (EPSs). This review provides an integrated perspective on EPS biosynthesis, function, and regulation in these organisms, emphasizing their critical role in survival and highlighting their ...
Tracey M Gloster, Ebru Toksoy Öner
wiley   +1 more source

The nicotinamide hypothesis revisited—plant defense signaling integrating PARP, nicotinamide, nicotinic acid, epigenetics, and glutathione

open access: yesFEBS Letters, EarlyView.
Nicotinamide (NIC) and nicotinic acid (NIA) are proposed as stress signaling compounds in plants. Oxidative stress may lead to single strand breaks (SSB) in DNA, which activate poly(ADP‐ribose) polymerase (PARP). NIC and NIA are then formed from NAD. NIC and NIA can promote epigenetic changes leading to the expression of defense genes specific for the ...
Torkel Berglund, Anna B. Ohlsson
wiley   +1 more source

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