Results 71 to 80 of about 3,248 (213)

The Psychedelic State Induced by Ayahuasca Modulates the Activity and Connectivity of the Default Mode Network [PDF]

, 2015
The experiences induced by psychedelics share a wide variety of subjective features, related to the complex changes in perception and cognition induced by this class of drugs. A remarkable increase in introspection is at the core of these altered states
Andrade, Katia C., Araujo, Draulio B. de, Crippa, Jose Alexandre S., Hallak, Jaime E. C., Palhano-Fontes, Fernanda, Ribeiro, Sidarta, Santos, Antonio C., Tofoli, Luis F.   +7 more
core   +6 more sources

Effect of Probiotics Supplementation on REM Sleep Behavior Disorder and Motor Symptoms in Parkinson's Disease: A Pilot Study

CNS Neuroscience &Therapeutics, Volume 31, Issue 7, July 2025.
Twelve‐week probiotics supplementation in Parkinson's disease (PD) patients demonstrated significant improvements in motor symptoms and REM sleep behavior disorder (RBD) symptoms. Additionally, the intervention exerted a modulatory effect on gut microbiota composition and plasma metabolite profiles, suggesting a potential role of probiotics in ...
Yitong Du, Lin Wang, Ying Cui, Xiaojiao Xu, Mingkai Zhang, Yue Li, Ting Gao, Dan Gao, Zhi Sheng, Shiya Wang, Houzhen Tuo   +10 more
wiley   +1 more source

Cytotoxic activity of methanolic extract and two alkaloids extracted from seeds of Peganum harmala L. [PDF]

, 2005
To study the cytotoxic activity of P. harmala. Materials and method: The alkaloids harmine and harmaline have been isolated from a methanolic extract from the seeds of P. harmala L.
Berrougui, Hicham, Ettaib, Abdelkader, Herrera González, María Dolores, López Lázaro, Miguel, Mamouchi, Mohamed, Martín Cordero, Carmen   +5 more
core  

In vitro monoamine oxidase inhibition potential of alpha- methyltryptamine analog new psychoactive substances for assessing possible toxic risks [PDF]

Tryptamines have emerged as new psychoactive substances (NPS), which are distributed and consumed recreationally without preclinical studies or safety tests.
Brandt, SD, Kavanagh, PV, Maurer, HH, Meyer, MR, Wagmann, L   +4 more
core   +1 more source

Psychedelics Promote Structural and Functional Neural Plasticity. [PDF]

, 2018
Atrophy of neurons in the prefrontal cortex (PFC) plays a key role in the pathophysiology of depression and related disorders. The ability to promote both structural and functional plasticity in the PFC has been hypothesized to underlie the fast ...
Barragan, Eden V, Burbach, Kyle F, Cameron, Lindsay P, Dennis, Megan Y, Duim, Whitney C, Gray, John A, Greb, Alexandra C, Ly, Calvin, McAllister, A Kimberley, Olson, David E, Ori-McKenney, Kassandra M, Paddy, Michael R, Soltanzadeh Zarandi, Sina, Sood, Alexander, Wilson, Paige C, Wong, Jonathan M   +15 more
core   +2 more sources

The Mechanism Exploration of Traditional Chinese Medicine's “Different Treatments for Same Disease” Concept in Osteoporosis Therapy: A Serum Metabolomics Study

Journal of Cellular and Molecular Medicine, Volume 29, Issue 13, July 2025.
ABSTRACT The “different treatments for same disease” is an important concept of traditional Chinese medicine (TCM) therapy. In TCM, osteoporosis (OP) treatment is aimed at invigorating blood, strengthening spleen, and tonifying kidneys, and their typical herbs are Angelica sinensis (Oliv.) Diels (Danggui, DG), Poria cocos (Schw.) Wolf (Fuling, FL), and
Jingyuan Wen, Xuefeng Li, Zhen Wu, Liu Jiangyuan, Guanyin Wang, Xu Wang, Zhengsheng Bao, Yang Yu, Pinger Wang, Zhenyu Shi, Bing Xu, Yunhuo Cai, Hongting Jin, Jiali Chen   +13 more
wiley   +1 more source

In vitro antiviral effects of Peganum harmala seed extract and its total alkaloids against Influenza virus [PDF]

, 2017
This research was aimed to evaluate the in vitro antiviral effect and the mechanism of the effect of Peganum. harmala seeds extract against influenza A virus infection using Madin-Darby canine kidney (MDCK) cells.
Fotouhi, F., Karimi, A., Moradi, M.-T., Rafieian-Kopaei, M.   +3 more
core   +1 more source

Plantamajoside Promotes NGF/TrkA Pathway to Inhibit Neuronal Apoptosis and Improve Diabetic Peripheral Neuropathy

Journal of Cellular and Molecular Medicine, Volume 29, Issue 8, April 2025.
ABSTRACT The symptoms caused by diabetic peripheral neuropathy (DPN) have severely impacted patients' quality of life. While plantamajoside (PMS) exhibits neuroprotective properties, its efficacy and molecular mechanisms against DPN are unexplored.
Qingshan Hai, Yuming Wang, Hanzhou Li, Huan Pei, Ning Wang, Xiaoxia Zhang, Mingyao Fan, Jiabao Liao, Weibo Wen, Jie Zhao, Ling Yang, Huantian Cui   +11 more
wiley   +1 more source

Harmaline-induced impairment of Pavlovian conditioning in the rabbit [PDF]

The Journal of Neuroscience, 1993
In this study we examined the effects of harmaline on Pavlovian conditioning of the rabbit's nictitating membrane response. The acquisition of conditioned responses was determined during a single session consisting of 120 pairings of a tone-conditioned stimulus with a corneal air puff unconditioned stimulus.
J A, Harvey, A G, Romano
openaire   +2 more sources

Alkaloid profile of Italian alpine milk

Journal of Food Science, Volume 90, Issue 2, February 2025.
Abstract This study examines the alkaloid profiles in alpine milk. Alkaloids could pose a health concern but also prove interesting from a geographic traceability perspective. Over three consecutive days, 48 daily milk samples were collected from 16 lactating cows grazing on two alpine pastures in Northeast Italy, with 8 cows from each pasture ...
Tiziana Nardin, Edi Piasentier, Alberto Romanzin, Francesca Martinelli, Roberto Larcher   +4 more
wiley   +1 more source