Results 121 to 130 of about 5,752 (199)

ZDWX-25, a dual DYRK1A/GSK3β inhibitor, attenuates tau hyperphosphorylation and neuroinflammation in acute mouse models. [PDF]

Front Pharmacol
Wang W, Xing Y, Xu Z, Liu S, Zhou L, Ning X, Li X, Zheng F, Yang A, Li Z, Ren M, Xu Z, Zhao Q.   +12 more
europepmc   +1 more source

In Silico and In Vitro Evaluation of Calm Supplement Constituents on Antidepressant-Related Molecular Targets and Neuroplasticity-Associated Gene Expression. [PDF]

Biomedicines
Batur LK, Pektas A, Aslan B, Akcali N, Mustafa Z, Bayarslan AU, Aldogan EH, Ustunova S.   +7 more
europepmc   +1 more source

Harmine Derivatives Alleviate LPS-Induced Acute Lung Injury via Targeting GSK3β. [PDF]

Inflammation
Ye X, Lin J, Zhang T, Chen H, Huang H, Cui L, Zhuang J, Zhang M, Liu W, Liu W, Wu L, Du B, Chen Y, Wu Q, Xu Z, Zeng X, Zhao Q.   +16 more
europepmc   +1 more source

Harmine Hydrochloride from <i>Peganum harmala</i> L. Targets NFAT1 for Proteasomal Degradation to Suppress Ovarian Cancer Progression. [PDF]

Pharmaceuticals (Basel)
Zhang X, Zhu H, Yu C, Huang S, Fang D.
europepmc   +1 more source

Evaluation of [¹⁸F]MK-6240 binding to tau protein in postmortem human brains of Down syndrome and Alzheimer's disease and assessment of off-target (non-tau) binding. [PDF]

Acta Neuropathol Commun
Karim F, Biju AP, Liang C, Santos CJ, Rajarethenam M, Mukherjee J.   +5 more
europepmc   +1 more source

Measurement of Tau Protein and Aβ Amyloid Plaques in Postmortem Human Brains of Down Syndrome and Alzheimer's Disease by Using [¹²⁵I]IPPI and [¹²⁵I]IBETA Autoradiography. [PDF]

Synapse
Biju AP, Karim F, Schafer DM, Sison SA, Liang C, Head E, Mukherjee J.   +6 more
europepmc   +1 more source

Targeting DYRK1A with rationally designed pyrazine-guanidine hybrids for Alzheimer's disease: design, synthesis, and biological evaluation. [PDF]

RSC Adv
Khan S, Khan S, Khan S, Rahman MA, Rahman A, Reza A, Khurana S, Ashraf MZ, Islam A, Hoda N.   +9 more
europepmc   +1 more source

Indole derivatives intervene osteoporosis via gut-bone axis. [PDF]

Front Cell Infect Microbiol
Wang W.
europepmc   +1 more source

Harmine suppresses the malignant phenotypes of Lewis lung carcinoma cells by inhibiting EGFR phosphorylation. [PDF]

Am J Transl Res
Zhang X, Wang T, Hu Y, Fu C, Lian X, Li Y, Zhao R.   +6 more
europepmc   +1 more source

Synthesis and Evaluation of Radioiodinated [¹²⁵I]7-Iodo-5H-Pyrido[4,3-B]Indole ([¹²⁵I]CTAU) in Postmortem Human Alzheimer's Disease Brain. [PDF]

J Labelled Comp Radiopharm
McNamara CC, Biju AP, Hipolito ELM, Nguyen NTB, Liang C, Mukherjee J.   +5 more
europepmc   +1 more source