Results 111 to 120 of about 4,342 (172)

Predicting drug-drug interactions between ayahuasca alkaloids and SSRIs using physiologically based pharmacokinetic modeling. [PDF]

Front Mol Biosci
Ribeiro GSG, Paranhos BAPB, Dörr F, Yonamine M, Villanova B, Guerra LTL, Raminelli AO, Reis JAS, de Paula CC, Zacharias ABV, Cecílio Hallak JE, Dos Santos RG, Martins FS, Marcourakis T.   +13 more
europepmc   +1 more source

DYRK1A inhibition restores pancreatic functions and improves glucose metabolism in a preclinical model of type 2 diabetes. [PDF]

Mol Metab
Bertrand R, Tolu S, Picot D, Tourrel-Cuzin C, Ouahab A, Dairou J, Deau E, Lindberg MF, Meijer L, Movassat J, Uzan B.   +10 more
europepmc   +1 more source

Harmine promotes axon regeneration through enhancing glucose metabolism. [PDF]

J Biol Chem
Liu R, Zhou B.
europepmc   +1 more source

Probing the Inhibitory Potential of Halogenated Symmetrical Formamidine Against MAO-A and MAO-B: Structural Elucidation, Molecular Dynamic Simulation and DFT Computational Studies. [PDF]

Chem Biodivers
Oladipo SD, Luckay RC, Olalekan SO, Badeji AA, Yusuf TL, Adeleke AA, Matinise N.   +6 more
europepmc   +1 more source

Unlocking the Power of Plant-Derived Natural Products: Therapeutic Benefits for Cognitive Health and Neuropsychiatric Symptoms in Dementia-Related Diseases. [PDF]

Plants (Basel)
Koyama S, Pham L, Murakawa Y, Ogawa Y, Terauchi K, Davis K.   +5 more
europepmc   +1 more source

Harmine hydrochloride induces G0/G1 cell cycle arrest and apoptosis in oral squamous carcinoma cells. [PDF]

Exp Ther Med
Lin W, Li Y, Huang H, Zhao P, Su Y, Fang CY.   +5 more
europepmc   +1 more source

Acute experiences and persisting psychological effects associated with an encapsulated DMT-harmala alkaloid combination: results of a phase 1 study. [PDF]

Sci Rep
Perkins D, Halman A, Urokohara A, Palumbo J, Low M, Ruffell S, Galvão-Coelho N, Collins L, Norman A, Sarris J.   +9 more
europepmc   +1 more source

Investigating the Inhibitory Potential of Halogenated Quinoline Derivatives against MAO‑A and MAO-B: Synthesis, Crystal Structure, Density Functional Theory, and Molecular Dynamics Simulations. [PDF]

ACS Omega
Oladipo SD, Luckay RC, Olalekan SO, Badeji AA, Matinise N, Tshikhudo F.   +5 more
europepmc   +1 more source

Mechanism of nimodipine in treating neurodegenerative diseases: in silico target identification and molecular dynamic simulation. [PDF]

Front Pharmacol
Zheng S, Wang Y, Tang S, Guo Y, Ma D, Jiang X.   +5 more
europepmc   +1 more source

Towards Imaging Tau Hyperphosphorylation: Is DYRK1A a Potential Target for Imaging Hyperphosphorylation of Tau? Molecular Modeling Assessment and Synthesis of [¹²⁵I]Radioiodinated DYRK1A Inhibitor. [PDF]

Molecules
Paclibar CG, Schafer DM, Biju AP, Karim F, Sison SA, Liang C, Ahmed ST, Mukherjee J.   +7 more
europepmc   +1 more source