Results 111 to 120 of about 5,636 (198)

Harmine-Based Therapies to Promote Beta Cell Regeneration

, 2019
Diabetes is a disease diagnosed by the inability to regulate blood glucose concentration. A primary cause of diabetes is loss of insulin-producing pancreatic cells, or beta cells, which permanently affects insulin production capacity.
Zlatanic, Viktor
core  

Harmine-izing immunity [PDF]

Nature Immunology, 2015
openaire   +1 more source

Inhibition of Dyrk1a attenuates type 1 diabetic cardiomyopathy via anti‑ferroptosis. [PDF]

Mol Med Rep
Chen J, Zhang W, Hong T, Wang J, Chen C, Zhang Y, Hu M, You N, Huang J.   +8 more
europepmc   +1 more source

Examining the pharmacokinetic and pharmacodynamic interaction of N,N-dimethyltryptamine and harmine in healthy volunteers: a factorial dose-escalation study

Ayahuasca, a traditional psychoactive Amazonian brew, usually contains N,N-dimethyltryptamine (DMT) and β-carboline (harmine, harmaline, tetrahydroharmine) monoamine oxidase inhibitors.
Jareño Redondo, Javier, Seifritz, Erich, Müller, Per, Puchkov, Maxim, Scheidegger, Milan, Dornbierer, Dario A., Mueller, Jovin, Dornbierer, Joëlle, Egger, Klemens, Äbelö, Angela, Aicher, Helena D., Meling, Daniel, Kost, Jonas, Smallridge, John, Quednow, Boris B., Rotz, Robin von   +15 more
core   +1 more source

Human and mouse regenerative macrophages enhance beta cell survival, function, and proliferation. [PDF]

Islets
Monajemi M, Craciun AS, Huang Q, Dai L, Mojibian M, Crome SQ, Verchere CB, Levings MK.   +7 more
europepmc   +1 more source

ZDWX-25, a dual DYRK1A/GSK3β inhibitor, attenuates tau hyperphosphorylation and neuroinflammation in acute mouse models. [PDF]

Front Pharmacol
Wang W, Xing Y, Xu Z, Liu S, Zhou L, Ning X, Li X, Zheng F, Yang A, Li Z, Ren M, Xu Z, Zhao Q.   +12 more
europepmc   +1 more source

The chemotherapy of derivatives of harmine and harmaline. II [PDF]

Biochemical Journal, 1934
openaire   +2 more sources

[Retracted] Treatment with harmine ameliorates functional impairment and neuronal death following traumatic brain injury. [PDF]

Mol Med Rep
Zhong Z, Tao Y, Yang H.
europepmc   +1 more source

In Silico and In Vitro Evaluation of Calm Supplement Constituents on Antidepressant-Related Molecular Targets and Neuroplasticity-Associated Gene Expression. [PDF]

Biomedicines
Batur LK, Pektas A, Aslan B, Akcali N, Mustafa Z, Bayarslan AU, Aldogan EH, Ustunova S.   +7 more
europepmc   +1 more source

Harmine Derivatives Alleviate LPS-Induced Acute Lung Injury via Targeting GSK3β. [PDF]

Inflammation
Ye X, Lin J, Zhang T, Chen H, Huang H, Cui L, Zhuang J, Zhang M, Liu W, Liu W, Wu L, Du B, Chen Y, Wu Q, Xu Z, Zeng X, Zhao Q.   +16 more
europepmc   +1 more source