Results 101 to 110 of about 7,262 (218)
Targeting Glutamate Uptake To Treat Alcohol Use Disorders [PDF]
, 2015 Alcoholism is a serious public health concern that is characterized by the development of tolerance to alcohol's effects, increased consumption, loss of control over drinking and the development of physical dependence.
Bell, Richard L. +3 more
core +2 more sources
Higher blood harmane (1-methyl-9H-pyrido[3,4-b]indole) concentrations correlate with lower olfactory scores in essential tremor [PDF]
, 2008 Harmane (1-methyl-9H-pyrido[3,4-b]indole), a neurotoxin, may be an environmental risk factor for essential tremor (ET). Harmane and related chemicals are toxic to the cerebellum.
Factor-Litvak, Pam +5 more
core +2 more sources
Journal of Integrative NeuroscienceBackground: Bone cancer pain (BCP) is a prevalent chronic pain condition and a common clinical symptom in patients with advanced cancer. It significantly affects the mobility and quality of life of patients; however, current treatments
Shuyao Zhang +7 more
doaj +1 more source
بررسی اثرات ضد تومور و تمايزی آلکالوييدهای هارمين و هارمالين روی سلولهای لوسميک درمان شده با ATRA و G-CSF [PDF]
, 2004 در لوسمی حاد تمايز سلولهای بدخيم متوقف شده و اين سلولها فقط تکثير میيابند. در سالهای اخير غير از شيمی درمانی ترکيبی، از عوامل تمايز دهنده، سيتوکينها و داروهای سيتوتوکسيک در درمان لوسمی حاد به خصوص لوسمی حاد پروميلوسيتی استفاده شده است.
ذاکر, فرهاد
core
In vitro antiviral effects of Peganum harmala seed extract and its total alkaloids against Influenza virus [PDF]
, 2017 This research was aimed to evaluate the in vitro antiviral effect and the mechanism of the effect of Peganum. harmala seeds extract against influenza A virus infection using Madin-Darby canine kidney (MDCK) cells.
Fotouhi, F. +3 more
core +1 more source
HeliyonSmall molecules as ligands target multifunctional ribonucleic acids (RNA) for therapeutic engagement. This study explores how the anticancer DNA intercalator harmine interacts various motifs of RNAs, including the single-stranded A-form poly (rA), the ...
Paromita Sarkar +7 more
doaj +1 more source
Binding of Harmine Derivatives to DNA: A Spectroscopic Investigation
Molecules, 2017 Harmine belongs to a group of β-carboline alkaloids endowed with antitumor properties. Harmine and its derivatives are thought to bind to DNA and interfere with topoisomerase activities. We investigated the base-dependent binding of harmine, and three of
Bruno Pagano +3 more
doaj +1 more source
The Therapeutic Potentials of Ayahuasca: Possible Effects against Various Diseases of Civilization [PDF]
, 2016 Ayahuasca is an Amazonian psychoactive brew of two main components. Its active agents are β-carboline and tryptamine derivatives. As a sacrament, ayahuasca is still a central element of many healing ceremonies in the Amazon Basin and its ritual ...
Bokor, Petra +2 more
core +2 more sources
AntioxidantsPseudomonas plecoglossicida causes bacterial hemorrhagic ascites in ayu (Plecoglossus altivelis), a lethal disease characterized by abdominal distension with hemorrhagic ascites, multifocal organ hemorrhages, and histopathologically evident ...
Yan-Jun Liu +8 more
doaj +1 more source
Shannon entropy of brain functional complex networks under the influence of the psychedelic Ayahuasca [PDF]
, 2016 The entropic brain hypothesis holds that the key facts concerning psychedelics are partially explained in terms of increased entropy of the brain's functional connectivity.
de Araujo, Draulio B. +4 more
core +6 more sources