Results 81 to 90 of about 5,636 (198)
Phytochemical Analysis, Volume 37, Issue 4, Page 507-535, June 2026.ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek +3 more
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, 2023 Bei Chen,1,2,* Mingzhi Yan,1,2,* Huijing Gao,1,2 Qin Ma,3 Lihua Li,4 Guodong Lü,1,2 Yuehong Gong,1,2 Limei Wen,1,2 Shaoquan Xu,5 Jianhua Wang,1,2 Jun Zhao1,2 1First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang, People’s ...
Yan M +10 more
core
Recent Approaches for the Synthesis of Pyridine and Quinoline Cores Present in Natural Products
Advanced Synthesis &Catalysis, Volume 368, Issue 10, 19 May 2026.An anthology of the most recent methods used to synthesize pyridines and quinolines found in natural products over the last decade. Pyridines, quinolines, and their derivatives represent a class of significant heterocyclic compounds that are prevalent in a multitude of natural products, including alkaloids found in plants, fungi, insects, marine ...
Carl Bowman +2 more
wiley +1 more source
Advanced Science, Volume 13, Issue 25, 4 May 2026.Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song +4 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 5, May 2026.Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200
Amal Elrherabi +8 more
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25 Years of “Loop” Radiochemistry for PET Imaging
Journal of Labelled Compounds and Radiopharmaceuticals, Volume 69, Issue 4-6, April‐May 2026.While conventional methods to 11C‐ and 18F‐labelled radiopharmaceuticals utilize a vial‐based approach, in the past quarter‐century, a modern, efficient, and cleaner “loop method” has been developed. The radiochemical diversity of reactions synthesized by the loop method are shown.
Emily Murrell, Sahil Khan, Neil Vasdev
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Über Harmin und Harmalin [PDF]
Berichte der deutschen chemischen Gesellschaft, 1914 n ...
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Molecular Oncology, Volume 20, Issue S1, Page 1-692, August 2026.Abstracts submitted to the ‘EACR 2026 Congress: Innovative Cancer Science’, from 08–11 June 2026 and accepted by the Congress Organising Committee are published in this Supplement of Molecular Oncology, an affiliated journal of the European Association for Cancer Research (EACR).
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Harmine shows therapeutic activity on nicotine-induced liver failure in mice [PDF]
, 2019 This experiment evaluated the effects of harmine against nicotine-induced damage to the liver of mice. Nicotine is a major toxic component of cigarette smoke and a major risk factor for functional disorders in the liver, because it induces oxidative ...
Gholami mahmoudian, Zahra +4 more
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Harmine suppresses the degradation of p53 and increases the accumulation of p53 in the nucleus.
, 2012 (A) Nuclear accumulation of p53 protein and MDM2 expression in HUVECs after harmine treatment for 48 hours. (B) Harmine prevented the degradation of p53 in HUVECs in the presence of CHX. (C) Harmine increased the nuclear levels of p53. Cells were treated
Zhengfang Yi (107425) +11 more
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