Results 71 to 80 of about 5,752 (199)
Ueber Harmin und Harmalin (III.) [PDF]
Berichte der deutschen chemischen Gesellschaft, 1889 n ...
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Scientific Reports, 2022 Type 1 diabetes (T1D) occurs as a consequence of the autoimmune destruction of insulin-producing pancreatic beta (β) cells and commonly presents with insulin deficiency and unregulated glycemic control.
Swati Mishra, Philip R. Streeter
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The parameters of the binding of harmine to MDM2.
, 2012 The parameters of the binding of harmine to MDM2.
Zhengfang Yi (107425) +11 more
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, 2022 This file contains spectroscopic and experimental images of Nicotine, Harmaline, Harmine, gallic acid, and caffeine with metal complexes.
Saad Salman (2086777)
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Molecules, 2020 The β-carboline alkaloid harmine is a potent DYRK1A inhibitor, but suffers from undesired potent inhibition of MAO-A, which strongly limits its application.
Anne Wurzlbauer +7 more
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Chemistry &Biodiversity, Volume 23, Issue 8, August 2026.This study performs in vivo and in silico assays with uliginosin B, targeting its activity in the Ras signaling pathway, demonstrating a possible allosteric interaction with the HRAS (human) and LET‐60 (nematode) proteins, and a decrease in the overexpression of the let‐60 gene in the nematode C. elegans.
Maria Eduarda O. De Souza +9 more
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Potential Antitumor Effect of Harmine in the Treatment of Thyroid Cancer [PDF]
, 2017 Thyroid cancer is one of the most common types of cancer in endocrine system. In latest studies, harmine has been proved to inhibit the growth of several cancers in vitro and in vivo. In the current study, we evaluated the in vitro and in vivo anticancer
Jianbo Li, Shu Ruan, Feng Jia
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Drug Development Research, Volume 87, Issue 5, August 2026.ABSTRACT A series of novel chiral urea and thiourea compounds were designed as multitarget‐directed ligands for Alzheimer's disease and evaluated against hAChE, hBChE, and hMAO‐B, with exploratory assessment of HSD10. These chiral compounds were synthesized and fully characterized, and their enantiopurity was confirmed via HPLC.
Sule Erol Gunal +10 more
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The harmala alkaloid harmine is a modulator of circadian Bmal1 transcription
, 2011 Biological rhythms are orchestrated by a cell-autonomous clock system that drives the rhythmic cascade of clock genes. We established an assay system using NIH 3T3 cells stably expressing the Bmal1 promoter-driven luciferase reporter gene and used it to ...
Yoshimitsu Yamazaki +3 more
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Protective effect of Harmine on kidney disorders induced by nicotine in male mice [PDF]
, 2018 Introduction: Harmine is one of the Harmal-deived alkaloids with anti-proliferatory effect on cell lines. Nicotine is a major toxic component of cigarette smoke and it is a major risk factor in the development of functional disorder of several organ ...
Jalili, Faramarz, Jalili, Cyrus
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