Results 51 to 60 of about 5,752 (199)

Innovative spectrofluorometric method for determination of harmaline and harmine in different matrices

open access: yesScientific Reports, 2023
Harmaline and harmine are naturally occurring closely related β-carboline alkaloids found in Peganum and Banisteriopsis plants. They have historical significance in traditional practices due to their potential psychoactive and therapeutic properties ...
Ahmed H. Abdelazim   +2 more
doaj   +1 more source

Harmine activates p53 by inducing phosphorylation of p53 and binding to MDM2.

open access: yes, 2012
(A) Chemical structure, molecular formula and 212.25 molecular weight of harmine. (B) MDM2-p53 interaction assay of harmine-treated HUVECs. After harmine treatment for 48 hours, the endogenous p53-MDM2 interaction was detected by a co-immunoprecipitation
Zhengfang Yi (107425)   +11 more
core   +1 more source

An experimental study of the systemic bioavailability of the drug "Harmin hydrochloride, capsules" in comparison with native garmin on chinchilla rabbits

open access: yesФармакокинетика и Фармакодинамика, 2020
An experimental comparative study of the relative bioavailability of plant alkaloid harmine (native, in the form of a base) in comparison with its derivative harmine hydrochloride was carried out on chinchilla rabbit.
S. M. Adekenov   +5 more
doaj   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

Harmine inhibits tumor growth and angiogenesis.

open access: yes, 2012
(A) Inhibition of solid tumor growth in harmine-treated xenograft mouse models. Images of solid tumors in control and experimental groups are shown. (B) The size of solid tumors was assessed in the absence or presence of harmine, and statistical results ...
Zhengfang Yi (107425)   +11 more
core   +1 more source

Harmine, an inhibitor of the type III secretion system of Salmonella enterica serovar Typhimurium

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
New therapeutic strategies for clinical Salmonella enterica serovar Typhimurium (S. Typhimurium) infection are urgently needed due to the generation of antibiotic-resistant bacteria.
Yunjia Shi   +9 more
doaj   +1 more source

Psychedelic‐assisted treatment for substance use disorder: A narrative systematic review

open access: yesAddiction, EarlyView.
Abstract Background and aims This is the first systematic review of the extant literature on all major psychedelic‐assisted treatment for alcohol use disorder (AUD), tobacco use disorder (TUD) and other substance use disorders (SUD). We aimed to summarise the evidence for efficacy of psychedelic‐assisted treatment for AUD, TUD, and SUD; to evaluate its
Theodore Piper   +7 more
wiley   +1 more source

Pancreatic β‐cell mitogenic regeneration in type 1 diabetes: A preclinical review

open access: yesDiabetic Medicine, EarlyView.
Abstract Type 1 diabetes (T1D) is caused by autoimmune destruction of insulin‐producing pancreatic β‐cells, resulting in hyperglycaemia. The first‐line treatment for symptomatic T1D is exogenous insulin replacement to maintain glycaemic control.
James Cantley   +3 more
wiley   +1 more source

Effect of harmine on nicotine-induced kidney dysfunction in male mice

open access: yesInternational Journal of Preventive Medicine, 2019
Background: The nicotine content of cigarettes plays a key role in the pathogenesis of kidney disease. Harmine is a harmal-derived alkaloid with antioxidant properties.
Mohammad Reza Salahshoor   +3 more
doaj   +1 more source

Jing Si Herbal Tea Aqueous Extract Modulates G‐CSF‐Induced Hematopoietic Stem and Progenitor Cells Mobilization and Mitigates Associated Pain in a Murine Model

open access: yesCell Biochemistry and Function, Volume 44, Issue 11, November 2026.
ABSTRACT Granulocyte colony‐stimulating factor (G‐CSF) is widely used for stem cell mobilization but is associated with side effects such as pain, which often discourages healthy donors. Jing Si Herbal Tea (JSHT), a novel Chinese herbal formula comprising eight different Chinese herbal medicines, has been shown to exert pleiotropic effects against ...
Ji‐Yan Lyu   +8 more
wiley   +1 more source

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