Results 51 to 60 of about 5,636 (198)

Cardiovascular and Respiratory Effects of Harmine

open access: yesExperimental Biology and Medicine, 1970
SummaryIntravenously administered harmine in cats, rats, and humans induced bradycardia and hypotension; cats exhibited apnea and ventricular arrhythmias. In the cat, bradycardia was eliminated by vagotomy and apnea by atropinization. The effects of acetylcholine and epinephrine were potentiated by harmine; possibly this was due to the inhibition of ...
T A, Slotkin, V, DiStefano
openaire   +2 more sources

Overcoming the clinical challenges of traditional ayahuasca: a first-in-human trial exploring novel routes of administration of N,N-Dimethyltryptamine and harmine

open access: yesFrontiers in Pharmacology, 2023
Recently, the Amazonian plant medicine “ayahuasca”—containing the psychedelic compound N,N-dimethyltryptamine (DMT) and numerous β-carboline alkaloids, such as harmine—has been suggested to exhibit beneficial effects in patients with affective and other ...
Dario A. Dornbierer   +23 more
doaj   +1 more source

Anti-Diabetic and Anti-Adipogenic Effect of Harmine in High-Fat-Diet-Induced Diabetes in Mice

open access: yesLife, 2023
One of the most important health issues facing the world today is obesity. It is an important independent risk factor for developing type 2 diabetes. Harmine offers various pharmacological effects, such as anti-inflammatory and anti-tumor effects.
Menna H. E. Morsy   +4 more
doaj   +1 more source

LXXIX.—Harmine and harmaline. Part III [PDF]

open access: yesJ. Chem. Soc., Trans., 1919
n ...
Perkin, William Henry, Robinson, Robert
openaire   +1 more source

Metabolic pathways of the psychotropic-carboline alkaloids, harmaline and harmine, by liquid chromatography/mass spectrometry and NMR spectroscopy

open access: yes, 2012
The β-carboline alkaloids, harmaline and harmine, are present in hallucinogenic plants Ayahuasca and Peganum harmala, and in a variety of foods. In order to establish the metabolic pathway and bioactivities of endogenous and xenobiotic bioactive β ...
Zhang, B.F.   +6 more
core   +1 more source

Ueber Harmin und Harmalin [PDF]

open access: yesBerichte der deutschen chemischen Gesellschaft, 1905
n ...
Fischer, O., Buck, C.-H.-R.
openaire   +2 more sources

Effects of Harmine on endothelial cell apoptosis

open access: yes, 2012
, G2/M arrest and proliferation. (A) The proportion of apoptotic cells was increased by harmine. Harmine induced cleavage of PARP and suppressed the expression of survivin and Bcl-2.
Zhengfang Yi (107425)   +11 more
core   +1 more source

Harmine Acts as an Indirect Inhibitor of Intracellular Protein Aggregation

open access: yes, 2020
Protein aggregation and oxidative stress are two pathological hallmarks of a number of protein misfolding diseases, including Huntington’s disease (HD).
Swati Jain (569859)   +3 more
core   +1 more source

Harmine inhibits tumor growth and angiogenesis.

open access: yes, 2012
(A) Inhibition of solid tumor growth in harmine-treated xenograft mouse models. Images of solid tumors in control and experimental groups are shown. (B) The size of solid tumors was assessed in the absence or presence of harmine, and statistical results ...
Zhengfang Yi (107425)   +11 more
core   +1 more source

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