Results 51 to 60 of about 5,636 (198)
Cardiovascular and Respiratory Effects of Harmine
SummaryIntravenously administered harmine in cats, rats, and humans induced bradycardia and hypotension; cats exhibited apnea and ventricular arrhythmias. In the cat, bradycardia was eliminated by vagotomy and apnea by atropinization. The effects of acetylcholine and epinephrine were potentiated by harmine; possibly this was due to the inhibition of ...
T A, Slotkin, V, DiStefano
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CCXXVI.—Harmine and harmaline. Part VI. The synthesis of N-methyltetrahydronorharmine and the constitution of harmaline and of the alkylated harmines [PDF]
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Kermack, William Ogilvy +2 more
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Recently, the Amazonian plant medicine “ayahuasca”—containing the psychedelic compound N,N-dimethyltryptamine (DMT) and numerous β-carboline alkaloids, such as harmine—has been suggested to exhibit beneficial effects in patients with affective and other ...
Dario A. Dornbierer +23 more
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Anti-Diabetic and Anti-Adipogenic Effect of Harmine in High-Fat-Diet-Induced Diabetes in Mice
One of the most important health issues facing the world today is obesity. It is an important independent risk factor for developing type 2 diabetes. Harmine offers various pharmacological effects, such as anti-inflammatory and anti-tumor effects.
Menna H. E. Morsy +4 more
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LXXIX.—Harmine and harmaline. Part III [PDF]
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Perkin, William Henry, Robinson, Robert
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The β-carboline alkaloids, harmaline and harmine, are present in hallucinogenic plants Ayahuasca and Peganum harmala, and in a variety of foods. In order to establish the metabolic pathway and bioactivities of endogenous and xenobiotic bioactive β ...
Zhang, B.F. +6 more
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Ueber Harmin und Harmalin [PDF]
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Fischer, O., Buck, C.-H.-R.
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Effects of Harmine on endothelial cell apoptosis
, G2/M arrest and proliferation. (A) The proportion of apoptotic cells was increased by harmine. Harmine induced cleavage of PARP and suppressed the expression of survivin and Bcl-2.
Zhengfang Yi (107425) +11 more
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Harmine Acts as an Indirect Inhibitor of Intracellular Protein Aggregation
Protein aggregation and oxidative stress are two pathological hallmarks of a number of protein misfolding diseases, including Huntington’s disease (HD).
Swati Jain (569859) +3 more
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Harmine inhibits tumor growth and angiogenesis.
(A) Inhibition of solid tumor growth in harmine-treated xenograft mouse models. Images of solid tumors in control and experimental groups are shown. (B) The size of solid tumors was assessed in the absence or presence of harmine, and statistical results ...
Zhengfang Yi (107425) +11 more
core +1 more source

