Results 31 to 40 of about 4,342 (172)

LXXIX.—Harmine and harmaline. Part III [PDF]

J. Chem. Soc., Trans., 1919
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Perkin, William Henry, Robinson, Robert
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Structure–Activity Relationships and Biological Evaluation of 7-Substituted Harmine Analogs for Human β-Cell Proliferation

Molecules, 2020
Recently, we have shown that harmine induces β-cell proliferation both in vitro and in vivo, mediated via the DYRK1A-NFAT pathway. We explore structure–activity relationships of the 7-position of harmine for both DYRK1A kinase inhibition and β-cell ...
Kunal Kumar, Peng Wang, Ethan A. Swartz, Susmita Khamrui, Cody Secor, Michael B. Lazarus, Roberto Sanchez, Andrew F. Stewart, Robert J. DeVita   +8 more
doaj   +1 more source

Cardiovascular and Respiratory Effects of Harmine

Experimental Biology and Medicine, 1970
SummaryIntravenously administered harmine in cats, rats, and humans induced bradycardia and hypotension; cats exhibited apnea and ventricular arrhythmias. In the cat, bradycardia was eliminated by vagotomy and apnea by atropinization. The effects of acetylcholine and epinephrine were potentiated by harmine; possibly this was due to the inhibition of ...
T A, Slotkin, V, DiStefano
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CXC.—Harmine and harmaline. Part I [PDF]

J. Chem. Soc., Trans., 1912
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Perkin, William Henry, Robinson, Robert
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Ueber Harmin und Harmalin [PDF]

Berichte der deutschen chemischen Gesellschaft, 1905
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Fischer, O., Buck, C.-H.-R.
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Overcoming the clinical challenges of traditional ayahuasca: a first-in-human trial exploring novel routes of administration of N,N-Dimethyltryptamine and harmine

Frontiers in Pharmacology, 2023
Recently, the Amazonian plant medicine “ayahuasca”—containing the psychedelic compound N,N-dimethyltryptamine (DMT) and numerous β-carboline alkaloids, such as harmine—has been suggested to exhibit beneficial effects in patients with affective and other ...
Dario A. Dornbierer, Dario A. Dornbierer, Dario A. Dornbierer, Laurenz Marten, Laurenz Marten, Jovin Mueller, Helena D. Aicher, Helena D. Aicher, Helena D. Aicher, Michael J. Mueller, Michael J. Mueller, Michael J. Mueller, Martina Boxler, Michael Kometer, Davor Kosanic, Robin von Rotz, Maxim Puchkov, Thomas Kraemer, Hans-Peter Landolt, Hans-Peter Landolt, Erich Seifritz, Erich Seifritz, Milan Scheidegger, Milan Scheidegger   +23 more
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Anti-Diabetic and Anti-Adipogenic Effect of Harmine in High-Fat-Diet-Induced Diabetes in Mice

Life, 2023
One of the most important health issues facing the world today is obesity. It is an important independent risk factor for developing type 2 diabetes. Harmine offers various pharmacological effects, such as anti-inflammatory and anti-tumor effects.
Menna H. E. Morsy, Zohour I. Nabil, Samah T. Darwish, Rasha A. Al-Eisa, Amir E. Mehana   +4 more
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CCXXVI.—Harmine and harmaline. Part VI. The synthesis of N-methyltetrahydronorharmine and the constitution of harmaline and of the alkylated harmines [PDF]

J. Chem. Soc., Trans., 1922
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Kermack, William Ogilvy, Perkin, William Henry, Robinson, Robert   +2 more
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Quantification of glycosaminoglycans using harmine extract from Peganum harmala L. in mucopolysaccharidoses researches

Biomedical and Biotechnology Research Journal
Background: Harmine is used in the quantification of glycosaminoglycans (GAGs) for the research on mucopolysaccharidoses (MPSs). Although this product is commercially available, researchers may consider preparing it under laboratory conditions when it is
Houda El Fissi, Fadoua Bouzid, Ikram Achqra, Mohammed Said Sebbar, Fouad Msanda, Mohamed Amine Serghini, Najat Alif   +6 more
doaj   +1 more source

Dynamic Changes of Endogenic or Exogenic β-Carboline Alkaloid Harmine in Different Mammals and Human in vivo at Developmental and Physiological States

Frontiers in Aging Neuroscience, 2022
ObjectiveSeveral β-carboline alkaloids (βCBs), such as harmine, harmaline, harmane, and nor-harmane, are effective for Alzheimer’s disease mouse models. They can be found in some plants, common foodstuffs, and blank plasma of various mammals.
Ning Cao, Shuping Li, Aimin Xu, Manlin Li, Xiaoguang Zou, Zunji Ke, Gang Deng, Xuemei Cheng, Changhong Wang   +8 more
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