Results 61 to 70 of about 4,342 (172)
Ueber Harmin und Harmalin (III.) [PDF]
n ...
openaire +3 more sources
ABSTRACT Primary brain tumors are life‐threatening diseases. Glioblastoma is the most aggressive type with a poor prognosis. Medulloblastoma is the most common pediatric brain tumor. While surgical treatments often result in recurrences owing to the complex nature of the tumor microenvironment, conventional treatments lower the quality of life of ...
Ilkay Irem Ozbek +3 more
wiley +1 more source
Recent Approaches for the Synthesis of Pyridine and Quinoline Cores Present in Natural Products
An anthology of the most recent methods used to synthesize pyridines and quinolines found in natural products over the last decade. Pyridines, quinolines, and their derivatives represent a class of significant heterocyclic compounds that are prevalent in a multitude of natural products, including alkaloids found in plants, fungi, insects, marine ...
Carl Bowman +2 more
wiley +1 more source
Tumor metastasis results from complex interactions between cancer cells and mechanical microenvironments. We propose a “nucleus‐centered, cross‐stage mechanical signal decoding” model, highlighting how nuclear mechanosensors interpret forces at different stages.
Linqi Song +4 more
wiley +1 more source
Moroccan medicinal plants with in silico‐approved aphrodisiac effects provide 94 phytochemicals. Docking against PDE5, AR, ERα, and aromatase gives top scores for lutein (−10.6), baicalein (−9.5), liquiritigenin (−9.2), and procyanidins (−9.7). ADMET filtering passes baicalein and liquiritigenin but excludes lutein and procyanidins. MD simulations (200
Amal Elrherabi +8 more
wiley +1 more source
25 Years of “Loop” Radiochemistry for PET Imaging
While conventional methods to 11C‐ and 18F‐labelled radiopharmaceuticals utilize a vial‐based approach, in the past quarter‐century, a modern, efficient, and cleaner “loop method” has been developed. The radiochemical diversity of reactions synthesized by the loop method are shown.
Emily Murrell, Sahil Khan, Neil Vasdev
wiley +1 more source
ANTIDEPRESSANT ACTION OF HARMINE HYDROCHLORIDE
The articles presents the results of antridepressant action of water-soluble form of harmine hydrochloride.
Zh. S. Nurmaganbetov +6 more
openaire +3 more sources
ABSTRACT Major Depressive Disorder (MDD) and chronic pain are independently debilitating conditions that frequently co‐occur. This comorbidity poses a significant clinical challenge, resulting in greater symptom severity, higher disability, and worse prognosis than either condition alone.
Jordana Kazdan +2 more
wiley +1 more source
Background As antimicrobial resistance (AMR) has become a global health crisis, new strategies against AMR infection are urgently needed. Quorum sensing (QS), responsible for bacterial communication and pathogenicity, is among the targets for anti ...
Pei Chen +4 more
doaj +1 more source
Synthetic Derivatives of Natural Alkaloid Harmine
The indole alkaloid harmine was extracted from underground part of Peganum harmala L. With the purpose of obtaining the new biological active derivatives on base of alkaloid harmine the chemical modification was carried out.
M. M. Ismagulova +4 more
doaj +1 more source

