Results 91 to 100 of about 7,262 (218)

Atherosclerosis: Pathophysiology and promising herbal remedies in traditional Persian medicine [PDF]

, 2016
Atherosclerosis is a progressive inflammatory disease and is considered as main reason of death and morbidity in worldwide. The common drugs which are used for treatment of atherosclerosis reveal side effects, therefore it is necessary to identify the ...
Asadi-Samani, Majid., Cheraghi, Mostafa.
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β-Carbolines. 2. Rate Constants of Proton Transfer from Multiexponential Decays in the Lowest Singlet Excited State of Harmine in Water As a Function of pH [PDF]

, 1996
The β-carbolines present a complex problem involving multiple equilibria in the excited state in hydrogen-bonding solvents including water. Three excited state species exist: neutral, cation, and zwitterion.
Becker, R. S., Burrows, H. D., Dias, A., Maçanita, A. L., Miguel, M. da Graça, Varela, A. P.   +5 more
core   +1 more source

An Integrated Evaluation Framework for Adult Heart Regeneration

Journal of Cellular and Molecular Medicine, Volume 30, Issue 6, March 2026.
ABSTRACT Myocardial infarction (MI) remains a primary global cause of mortality due to irreversible cardiomyocyte loss. While promoting endogenous regeneration offers a highly promising therapy, its validation is critically hindered by the lack of standardised, comprehensive methodologies for quantitative assessment.
Yixun Li, Xinchang Liu, Xianliang Zhou, Yu Nie, Jie Feng   +4 more
wiley   +1 more source

CD168 Identifies Proliferating Pancreatic Islet Cells in Murine and Human

Advanced Science, Volume 13, Issue 10, 18 February 2026.
This study identifies CD168 as a conserved surface marker for proliferating β‐cells in mouse, human islets, and pancreatic islet tumors. CD168⁺ cells show high proliferation and low insulin expression. CD168+ cells form mostly uni‐β lineage clones, and some of the clones are multi‐lineage.
Shubo Yuan, Jiafu Li, Min Shao, Haili Bao, Ajun Geng, Jialin Yang, Yu Tao, Xinyi Chen, Tianxiong Xiao, Chunye Liu, Zhiyao Xie, Wenqian Song, Qing Cissy Yu, Hongxing Fu, Xu Han, Taochen He, Wenquan Wang, Jianfeng Chen, Sheng Yan, Shaohua Song, Liang Liu, Yi Arial Zeng   +21 more
wiley   +1 more source

Antioxidant, Anti‐inflammatory, Analgesic, and Antiarthritic Potentialities of Methanolic Extract of Fruit Husk of Nypa fruticans Wurmb, Established by In Silico Analysis

BioMed Research International, Volume 2026, Issue 1, 2026.
This study investigates the bioactive components and biological activities of the methanolic husk extract of Nypa fruticans Wurmb (MNF) through gas chromatography–mass spectrometry (GC‐MS) analysis. The MNF extract was identified to contain several bioactive components, including alkaloids, glycosides, phenols, tannins, and resins, as established ...
Farhana Alam Ripa, Ajoy Paul Adar, Adwiza Chakraborty Bishakha, Nashrah Mustafa, Mehrin Haque Tanisha, Nishat Zareen Khair, Zara Sheikh, Asef Raj, Israt Jahan Bulbul, Baisakhi Banerjee   +9 more
wiley   +1 more source

Licochalcone A as Novel Multitarget Inhibitors via AChE, BuChE, and Synapsin III for Therapeutic Intervention Against Alzheimer’s Disease: Computer‐Aided Drug Design

Journal of Chemistry, Volume 2026, Issue 1, 2026.
Alzheimer’s disease (AD) is characterized by key pathological features, including cholinergic dysfunction, amyloid‐beta (Aβ) aggregation, and disrupted synaptic transmission, positioning proteins such as acetylcholinesterase (AChE), butyrylcholinesterase (BuChE), and Synapsin III as critical targets for therapeutic strategies.
Ali Alimari, Bagher Seyedalipour, Payam Baziyar, Ehsan Joz Jalalian, Sohini Basu Roy   +4 more
wiley   +1 more source

Hypoxia‐Induced circPRELID2 Promotes Gastric Cancer Metastasis by Facilitating ZEB2 Translation via PCBP1 O‐GlcNAcylation

Advanced Science, Volume 12, Issue 46, December 11, 2025.
Under hypoxia, HIF1A is directly bound to the PRELID2 promoter to increase PRELID2 pre‐mRNA expression, followed by the DYRK1A–SFPQ–SAM68 complex binding to Alu‐containing introns in PRELID2 pre‐mRNA, leading to circPRELID2 circularization. CircPRELID2 interacts with PCBP1 and promotes its cytoplasmic retention.
Pengshan Zhang, Zai Luo, Yitian Xu, Yuan Zhang, Renchao Zhang, Nadina Paerhati, Shaopeng Zhang, Qianqian Cai, Zhengjun Qiu, Chen Huang   +9 more
wiley   +1 more source

Periosteum Organoid: Biomimetic Design Inspired From the Bone Healing Process

Exploration, Volume 5, Issue 6, December 2025.
Periosteum is a key factor in bone regeneration and repair, and the development of periosteum organoids with the help of organoid technology can achieve accelerated bone regeneration. This review explores the structure and function of the periosteum, the design and application of periosteum organoids, and their potential integration with bone organoids,
Shuyue Hao, Fuxiao Wang, Jingtao Huang, Zhidao Xia, James T. Triffitt, Chenjie Xu, Long Bai, Jiacan Su   +7 more
wiley   +1 more source

Anti fungal activity of alcoholic extract of Peganum harmala seeds [PDF]

, 2011
In our study, it was aimed to determine antifungal activity of Peganum harmala on medically important yeasts and molds in vitro. Fungal suspensions of Candida spp and aspergillus spp isolated from the clinical specimens were treated with serial dilutions
Diba, K., Khorshivand, Z., Shabatkhori, M., Shoar, M.G.   +3 more
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Natural products for the treatment of Type 2 Diabetes Mellitus [PDF]

, 2015
Type 2 diabetes mellitus is a metabolic disease characterized by persistent hyperglycemia. High blood sugar can produce long-term complications such as cardiovascular and renal disorders, retinopathy, and poor blood flow. Its development can be prevented
Barrios, José Luis, Francini, Flavio, Schinella, Guillermo Raúl   +2 more
core   +2 more sources