Results 131 to 140 of about 4,328 (171)
Some of the next articles are maybe not open access.
Effects of tremorine and harmine in the chick
European Journal of Pharmacology, 1967Abstract Tremorine produced pronounced tremor, akinesia, hypothermia and parasympathetic effects in young chicks. Tremor was recorded quantitatively and the tremor response to tremorine was found to diminish with increasing age and with repeated dosage.
W C, Bowman, G, Osuide
openaire +2 more sources
Pharmacological effects of harmine and its derivatives: a review
Archives of Pharmacal Research, 2020Harmine is isolated from the seeds of the medicinal plant, Peganum harmala L., and has been used for thousands of years in the Middle East and China. Harmine has many pharmacological activities including anti-inflammatory, neuroprotective, antidiabetic, and antitumor activities.
Liang, Zhang +2 more
exaly +3 more sources
Harmine Action in Rats with Lymphostatic Encephalopathy
Pharmacology, 2008In rats with lymphostatic encephalopathy the duration of harmine tremor was lengthened, and the brain concentrations of harmine decreased more slowly than in sham-operated controls. The tremor began simultaneously in both rat groups at coinciding brain concentrations of harmine.
G, Back, G, Seidel
openaire +2 more sources
An investigation of the tremorgenic actions of harmine in the rat
European Journal of Pharmacology, 1971Abstract Antagonism of harmine tremor by drugs which interfere with adrenergic nervous function was investigated in rats. Reserpine, diethyldithiocarbamic acid and propranolol reduced the intensity of the tremor without abolishing it completely. Phenoxybenzamine, mebanazine and atropine were without effect.
B, Cox, D, Potkonjak
openaire +2 more sources
The Harmine Group of Alkaloids
1937Harmine and harmaline are alkaloids found in the seeds of Peganum harmala and the pharmacological actions of these alkaloids, as well as of many artifically prepared derivatives of them, have now been investigated in considerable detail. The seeds of the plant have been used therapeutically for centuries and a brief reference to this earlier history ...
openaire +1 more source
Pharmacokinetics in the rat of the hallucinogenic alkaloids harmine and harmaline
Naunyn-Schmiedeberg's Archives of Pharmacology, 19741. After i. v. injection in rats, harmine and harmaline were distributed in the organism within a few seconds. In spite of the close chemical relationship, both alkaloids revealed significant pharmacokinetic differences. 2. Highest concentrations occurred for harmine in the lung and for harmaline in the kidney.
G, Zetler, G, Back, H, Iven
openaire +2 more sources
Biodistribution and radiation dosimetry of 11C-harmine in baboons
Nuclear Medicine Communications, 2007Monoamine oxidase A is a mitochondrial enzyme which is responsible for the metabolism of catecholamines such as dopamine, norepinephrine, as well as serotonin. This study describes the biodistribution and dosimetry of 11C-harmine, a tracer designed to specifically bind to monoamine oxidase A for positron emission tomography imaging.Three baboon studies
Rajan, Murthy +5 more
openaire +2 more sources
Harmine as a substitute for 33258 Hoechst in the FPG technique
Histochemistry, 1988We studied the effectiveness of harmine as a substitute for 33258 Hoechst in the fluorescence-plus-Giemsa technique, using Allium cepa chromosomes after 5-bromo-2'-deoxyuridine (BrdU) incorporation. Harmine showed a photosensitizing capacity which was somewhat higher than 33258 Hoechst and used half of the time established for the usual treatment.
M G, Gutiérrez-Gonzálvez +2 more
openaire +2 more sources
A MODEL OF HARMINE METABOLISM IN THE RAT
The Journal of Pharmacology and Experimental Therapeutics, 1970T A, Slotkin, V, DiStefano
openaire +2 more sources