Results 91 to 100 of about 1,936,197 (337)

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Physicochemical Properties and Storage Stability of Restructured Products Prepared from Mantis Shrimp at Refrigerated Temperature (4±1°C)

open access: yesInternational Journal of Bio-Resource and Stress Management
The experiment was conducted from January to August, 2023 at Central Institute of Fisheries Education, Mumbai, Maharashtra, India, to evaluate nutritionally rich restructured fish products, such as sausages, using mantis shrimp (Miyakella nepa).
D. Varsha   +6 more
doaj   +1 more source

2013 Oregon Wine Harvest Report [PDF]

open access: yes, 2013
This harvest report for the Oregon wine industry from 2013 describes the season as a play in two acts, with a wet intermission. Vintners were surprised by record rainfall one weekend in late September after a warm and dry summer.
Oregon Wine Board
core   +1 more source

Use of Posterior Hamstring Harvest During Anterior Cruciate Ligament Reconstruction in the Pediatric and Adolescent Population. [PDF]

open access: yes, 2018
Background:Posterior hamstring harvest has been described in the adult population in a limited fashion, but no study is available describing the use of posterior hamstring harvest in an active pediatric and adolescent cohort.
Janghala, Abhinav   +2 more
core   +2 more sources

Microbes Promote Amino Acid Harvest to Rescue Undernutrition in Drosophila.

open access: yesCell Reports, 2015
Microbes play an important role in the pathogenesis of nutritional disorders such as protein-specific malnutrition. However, the precise contribution of microbes to host energy balance during undernutrition is unclear.
R. Yamada   +4 more
semanticscholar   +1 more source

Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity

open access: yesMolecular Oncology, EarlyView.
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung   +17 more
wiley   +1 more source

High value fermented nutraceutical product from pomegranate aril and rind blends

open access: yesEnvironment Conservation Journal, 2019
Nutraceutical enriched blended beverages were prepared by using different fruit combination of pomegranate, jamun, kokum and pomegranate rind powder, where the TSS (14 °B) was maintained by using raisin syrup.
M Karan,   +4 more
doaj   +1 more source

Gravel galore: Impacts of clear-cut logging on salmon and their habitats [PDF]

open access: yes, 2002
Timber harvest may have both direct and indirect effects on salmon, and with a few exceptions those effects result in lowered survival of salmon in their stream habitats compared with unlogged forest (Hicks et al. 1991b).
Hicks, Brendan J.
core   +1 more source

Optimal forest rotation age under efficient climate change mitigation

open access: yes, 2015
This paper considers the optimal rotation of forests when the carbon flows of forest growth and harvest are priced with an increasing price. Such an evolution of carbon price is generally associated with economically efficient climate change mitigation ...
Ekholm, Tommi
core   +1 more source

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

open access: yesMolecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang   +3 more
wiley   +1 more source

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