Results 71 to 80 of about 524,624 (282)
Analysis of workplace injuries in Slovakian state forestry enterprises
Open Engineering, 2019 The aim of the paper is to identify the most common workplace accidents regarding injured body parts with respect to anthropometric data measurements of the population in the Slovak republic.
Gejdoš Miloš, Vlčková Mária
doaj +1 more source
Entropy, 2013 The paper introduces the notion of “entropy harvesting” in physical and biological systems. Various physical and natural systems demonstrate the ability to decrease entropy under external stimuli. These systems, including stretched synthetic polymers, muscles, osmotic membranes and suspensions containing small hydrophobic particles, are called ...
openaire +2 more sources
Finding novel vulnerabilities of hypomorphic BRCA1 alleles
Molecular Oncology, EarlyView.Synthetic lethality screens performed to identify novel vulnerabilities often model complete gene loss, thereby overlooking patient‐derived hypomorphic mutations. In this study, we have performed genome‐wide CRISPR screens on BRCA1 hypomorphic mutations, showing BRCA1I26A behaves like wild‐type, while BRCA1R1699Q mimics deficiency. Furthermore, we have
Anne Schreuder +10 more
wiley +1 more source
Human Energy Harvesting in the Urban Environment [PDF]
, 2015 The overall aim of the thesis was to provide a holistic view of the potential for electrical energy generation from harvesting of human mechanical work in the urban environment.
Partridge, JS
core
MITF maintains genome stability in nonmelanocyte lineages
Molecular Oncology, EarlyView.MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir +13 more
wiley +1 more source
Next MaterialsMercury is considered as the most hazardous pollutant due to its adverse effects to mankind. Hence the present work aims at the preparation and characterization of ball milled chicken eggshell derived activated carbon (ACESP) / halloysite nanotubes (HNT)
Jeya M. Peter Paul +3 more
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Oncogenic DMTF1β promotes cancer cell motility by regulating autophagy through ULK1 stabilization
Molecular Oncology, EarlyView.In the current study, we demonstrate that the oncogene DMTF1β regulates ULK1 stability by reducing its proteasomal degradation in cancer cells. This stabilization enables ULK1 to induce autophagy, which in turn facilitates cancer cell migration. Consequently, reduced DMTF1β levels lead to decreased autophagy and impaired cancer cell migration.
Jun Xu +13 more
wiley +1 more source
Plant diversity and precipitation gradients drive litter return and SOC in alpine vegetation
Carbon Balance and ManagementClimate and plant diversity are the major drivers of litter return and soil organic carbon (SOC) content. However, in cold and arid regions, how plant diversity and climate are affected by other factors and their contribution rates to the regulation of ...
Zhao Ding +5 more
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Applied SciencesFast-growing invasive tree species management produces a significant amount of low-density and low-value biomass, which offers a chance for waste valorization in the environmentally friendly construction sector.
Vasiliki Kamperidou +2 more
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Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer
Molecular Oncology, EarlyView.Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola +11 more
wiley +1 more source