Results 91 to 100 of about 6,289,424 (361)

Stochastic Ordering of Exponential Family Distributions and Their Mixtures

open access: yes, 2009
We investigate stochastic comparisons between exponential family distributions and their mixtures with respect to the usual stochastic order, the hazard rate order, the reversed hazard rate order, and the likelihood ratio order.
Hardy   +6 more
core   +1 more source

Impact of Delayed Completion of Previously Initiated Therapy and Provider Type on Outcomes of Root Canal Treatment [PDF]

open access: yes, 2020
Objective:if the provider type influences long-term outcomes in instances where NSRCT has been previously initiated. The primary purpose of this study was to determine if the period of time between previously initiated therapy and the completion of non ...
Sulim, Igor
core   +1 more source

Hazard Ratio Estimation in Small Samples

open access: yesStatistics in Biopharmaceutical Research, 2018
When comparing survival times between groups in the setting of proportional hazards, the Cox model is typically used for estimation and inference, the latter based on large sample considerations. Mehrotra and Roth introduced a generalized log-rank (GLR) method for better statistical efficiency in estimating relative risk in small samples.
Rengyi Xu   +2 more
openaire   +2 more sources

The epithelial barrier theory proposes a comprehensive explanation for the origins of allergic and other chronic noncommunicable diseases

open access: yesFEBS Letters, EarlyView.
Exposure to common noxious agents (1), including allergens, pollutants, and micro‐nanoplastics, can cause epithelial barrier damage (2) in our body's protective linings. This may trigger an immune response to our microbiome (3). The epithelial barrier theory explains how this process can lead to chronic noncommunicable diseases (4) affecting organs ...
Can Zeyneloglu   +17 more
wiley   +1 more source

Do higher solvency ratios reduce the costs of bailing out insured banks? [PDF]

open access: yes, 2003
The relationship between solvency constraints and bank behaviour in the presence of fixed rate deposit insurance is investigated. A rise in the minimum solvency ratio does not necessarily reduce the adverse consequences of moral hazard: bank efficiency ...
Eastwood, Robert
core   +2 more sources

Limitations of hazard ratios in clinical trials

open access: yesEuropean Heart Journal, 2018
Abstract
John M Aalen   +4 more
openaire   +3 more sources

From omics to AI—mapping the pathogenic pathways in type 2 diabetes

open access: yesFEBS Letters, EarlyView.
Integrating multi‐omics data with AI‐based modelling (unsupervised and supervised machine learning) identify optimal patient clusters, informing AI‐driven accurate risk stratification. Digital twins simulate individual trajectories in real time, guiding precision medicine by matching patients to targeted therapies.
Siobhán O'Sullivan   +2 more
wiley   +1 more source

Rationing of iodine content in kelp layers and products based on them. Changing approaches within the framework of a risk-based strategyin drug quality control

open access: yesФармация и фармакология (Пятигорск)
The State Pharmacopoeia of the Russian Federation regulates the lower level of iodine content in Laminaria thalli. However, an excess of iodine is as harmful to the human body as its deficiency.The aim.
V. M. Shchukin   +3 more
doaj   +1 more source

Breast cancer risk is increased in the years following false-positive breast cancer screening [PDF]

open access: yes, 2017
A small number of studies have investigated breast cancer (BC) risk among women with a history of false-positive recall (FPR) in BC screening, but none of them has used time-to-event analysis while at the same time quantifying the effect of false ...
Akl   +25 more
core   +2 more sources

A hazard ratio was estimated by a ratio of median survival times, but with considerable uncertainty [PDF]

open access: yesJournal of Clinical Epidemiology, 2014
To evaluate the empirical concordance between the hazard ratio (HR) and the median ratio (MR) in survival cancer studies.We selected all cancer survival articles from the New England Journal of Medicine published between 2000 and 2010. The qualitative concordance was estimated by the proportion of measured pairs in which the treatment effects for the ...
Cortés Martínez, Jordi   +3 more
openaire   +5 more sources

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