Results 101 to 110 of about 6,418,358 (332)

Hazard Ratio in Clinical Trials

Antimicrobial Agents and Chemotherapy, 2004
Time-to-event curves analyzed by Cox proportional hazards regression are commonly used to describe the outcome of drug studies. This methodology has the advantage of using all available information, including patients who fail to complete the trial, such
S. Spruance, J. Reid, M. Grace, M. Samore   +3 more
semanticscholar   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Risk Factors for Development of Chronic Kidney Disease in Cats [PDF]

, 2016
BACKGROUND: Identification of risk factors for development of chronic kidney disease (CKD) in cats may aid in its earlier detection. HYPOTHESIS/OBJECTIVES: Evaluation of clinical and questionnaire data will identify risk factors for development of ...
Abraham, Adams, Bang, Bartlett, Boor, Brown, Chambrone, Culhaci, D'Agata, DeBowes, Dibartola, Dibartola, Dow, Dow, Erlinger, Finco, Finco, Fisher, Fisher, Fox, Greene, Gunn-Moore, H.M. Syme, Habacher, Haroun, Heiene, Hoek, Hughes, J. Elliott, James, Jepson, Kulldorff, Lappin, Lappin, Lawler, Lindeman, Lulich, N.C. Finch, Obermayr, Pavlica, Poli, Poli, Powe, Rose, Rowe, Taal, Tonelli, Wakeling, White, Whittemore   +49 more
core   +2 more sources

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

A Sensitivity Analysis Approach for the Causal Hazard Ratio in Randomized and Observational Studies [PDF]

, 2022
Rachel Axelrod, Daniel Nevo
openalex   +1 more source

Breast cancer risk is increased in the years following false-positive breast cancer screening [PDF]

, 2017
A small number of studies have investigated breast cancer (BC) risk among women with a history of false-positive recall (FPR) in BC screening, but none of them has used time-to-event analysis while at the same time quantifying the effect of false ...
Akl, Alamo-Junquera, Bangsboll-Andersen, Barlow, Blanch, Burrell, Castells, Castells, Christiansen, Ciatto, Duijm, Goossens, Haesook, Haward, Henderson, Hofvind, Marmot, Mathieu, Maxwell, Peeters, Perry, Purushotham, Putter, Verduijn, von Euler-Chelpin, von Euler-Chelpin   +25 more
core   +2 more sources

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Risk Associations between Air Pollution Exposure and Cardiovascular Diseases: A Residential Retrospective Cohort Study

Atmosphere
The population of the Venafro Valley (Southern Italy) faces various type of air pollution problems (industrial facilities, traffic, and biomass combustion).
Elisa Bustaffa, Cristina Mangia, Liliana Cori, Marco Cervino, Fabrizio Bianchi, Fabrizio Minichilli   +5 more
doaj   +1 more source

What Should We Consider Carefully When Performing Survival Analysis?

Clinical Pediatric Hematology-Oncology, 2019
The survival data and the survival analysis are the data and analysis methods used to study the probability of survival. The survival data consist of a period from the juncture of a start event to the juncture of the end event (occurrence event).
Sang Gyu Kwak, Eun Jin Choi
doaj   +1 more source

Longitudinal Analysis of Quality of Life, Clinical, Radiographic, Echocardiographic, and Laboratory Variables in Dogs with Preclinical Myxomatous Mitral Valve Disease Receiving Pimobendan or Placebo: The EPIC Study [PDF]

, 2018
Background: Changes in clinical variables associated with the administration of pimobendan to dogs with preclinical myxomatous mitral valve disease (MMVD) and cardiomegaly have not been described. Objectives: To investigate the effect of pimobendan on
Abbott, J A, Barrett, K A, Bomassi, E, Bonagura, J D, Boswood, A, Church, W M, Deinert, M, Estrada, A H, Fernández-Del Palacio, M J, Fox, P R, Fujii, Y, Gordon, S G, Häggström, J, Jaudon, J P, Keene, B W, Kresken, J-G, Ljungvall, I, Luethy, M W, MacDonald, K A, Menaut, P, Moise, N S, O'Sullivan, M L, Oyama, M A, Patteson, M, Rosenthal, S L, Rush, J, Sanderson, K, Santilli, R A, Saunders, A B, Schummer, C, Smith, S, Spier, A, Stepien, R L, Szatmári, V, Tidholm, A, Uechi, M, Watson, P, Wess, G, Woolley, R   +38 more
core   +2 more sources