Results 121 to 130 of about 6,212,855 (344)

Cell‐free DNA aneuploidy score as a dynamic early response marker in prostate cancer

Molecular Oncology, EarlyView.
mFast‐SeqS‐based genome‐wide aneuploidy scores are concordant with aneuploidy scores obtained by whole genome sequencing from tumor tissue and can predict response to ARSI treatment at baseline and, at an early time point, to ARSI and taxanes. This assay can be easily performed at low cost and requires little input of cfDNA. Cell‐free circulating tumor
Khrystany T. Isebia, Anouk C. de Jong, Lisanne F. van Dessel, Vanja de Weerd, Corine Beaufort, Jean Helmijr, José Alberto Nakauma‐González, Job van Riet, Paul Hamberg, Daniel Vis, Michiel S. van der Heijden, Nick Beije, Martijn P. Lolkema, Teoman Deger, Saskia M. Wilting, Ronald de Wit, Maurice P. H. M. Jansen, John W. M. Martens   +17 more
wiley   +1 more source

Increased Risk of Inflammatory Bowel Disease Among Patients With Ankylosing Spondylitis: A 13-Year Population-Based Cohort Study

Frontiers in Immunology, 2020
AimAnkylosing spondylitis (AS) primarily affects the axial skeleton and extraarticular structures. Small-scaled studies have reported that the incidence and prevalence of inflammatory bowel disease (IBD) are higher in patients with AS than in the general ...
Shuya Wang, Hsi-Kai Tsou, Hsi-Kai Tsou, Jeng-Yuan Chiou, Yu-Hsun Wang, Zhiyi Zhang, James Cheng-Chung Wei, James Cheng-Chung Wei, James Cheng-Chung Wei, James Cheng-Chung Wei   +9 more
doaj   +1 more source

Multivariate hazard orderings of discrete random vectors [PDF]

The task of comparing two random vectors with respect to some multivariate stochastic ordering usually involves an infinite number of comparisons. Dyckerhoff and Mosler (1997) proved that, when the random vectors have finite supports, this task, for some
Colangelo Antonio
core  

Polygenic hazard score to guide screening for aggressive prostate cancer: development and validation in large scale cohorts. [PDF]

, 2018
OBJECTIVES: To develop and validate a genetic tool to predict age of onset of aggressive prostate cancer (PCa) and to guide decisions of who to screen and at what age.

core   +2 more sources

Response to neoadjuvant chemotherapy in early breast cancers is associated with epithelial–mesenchymal transition and tumor‐infiltrating lymphocytes

Molecular Oncology, EarlyView.
Epithelial–mesenchymal transition (EMT) and tumor‐infiltrating lymphocytes (TILs) are associated with early breast cancer response to neoadjuvant chemotherapy (NAC). This study evaluated EMT and TIL shifts, with immunofluorescence and RNA sequencing, at diagnosis and in residual tumors as potential biomarkers associated with treatment response.
Françoise Derouane, Jérôme Ambroise, Cédric van Marcke, Mieke Van Bockstal, Martine Berlière, Christine Galant, Hélène Dano, Médina Lougué, Elena Benidovskaya, Guy Jerusalem, Vincent Bours, Claire Josse, Jérôme Thiry, Aurélie Daumerie, Caroline Bouzin, Cyril Corbet, François P. Duhoux   +16 more
wiley   +1 more source

Hazard ratio funnel plots for survival comparisons [PDF]

Journal of Epidemiology & Community Health, 2009
Funnel plots are a form of control chart that give a snapshot of many institutions at a particular moment in time. This paper describes how funnel plots may be constructed for survival analyses based on hazard ratios obtained from a Cox regression model with adjustment for covariates and allowance for overdispersion.Analysis of simulated and real ...
openaire   +3 more sources

Peripheral blood proteome biomarkers distinguish immunosuppressive features of cancer progression

Molecular Oncology, EarlyView.
Immune status significantly influences cancer progression. This study used plasma proteomics to analyze benign 67NR and malignant 4T1 breast tumor models at early and late tumor stages. Immune‐related proteins–osteopontin (Spp1), lactotransferrin (Ltf), calreticulin (Calr) and peroxiredoxin 2 (Prdx2)–were associated with systemic myeloid‐derived ...
Yeon Ji Park, Jae Won Oh, Hyewon Chung, Jung Won Kwon, Yi Rang Na, Kwang Pyo Kim, Seung Hyeok Seok   +6 more
wiley   +1 more source

Tinnitus Among Patients With Anxiety Disorder: A Nationwide Longitudinal Study

Frontiers in Psychiatry, 2020
ObjectivesThe association between tinnitus and anxiety disorder remains debated. We used a retrospective cohort study to investigate the relationship between anxiety disorder and tinnitus, aiming to decipher possible risk factors for tinnitus in patients
Sheue-Jane Hou, Sheue-Jane Hou, Albert C. Yang, Albert C. Yang, Shih-Jen Tsai, Shih-Jen Tsai, Shih-Jen Tsai, Cheng-Che Shen, Cheng-Che Shen, Tsuo-Hung Lan, Tsuo-Hung Lan   +10 more
doaj   +1 more source

Characterizations of Distribution of Ratio of Rayleigh Random Variables [PDF]

, 2013
Various characterizations of the distribution of the ratio of two independent Rayleigh random variables are presented. These characterizations are based, on a truncated moment; on hazard function; and on certain functions of order ...
Hamedani, Gholamhossein
core   +1 more source

A novel RNA in situ hybridization assay for the long noncoding RNA SChLAP1 predicts poor clinical outcome after radical prostatectomy in clinically localized prostate cancer. [PDF]

, 2014
Long noncoding RNAs (lncRNAs) are an emerging class of oncogenic molecules implicated in a diverse range of human malignancies. We recently identified SChLAP1 as a novel lncRNA that demonstrates outlier expression in a subset of prostate cancers ...
Cao, Xuhong, Chinnaiyan, Arul, Feng, Felix, Iyer, Matthew, Jiang, Hui, Mehra, Rohit, Prensner, John, Sahu, Anirban, Shi, Yang, Siddiqui, Javed, Udager, Aaron, Wei, John   +11 more
core   +1 more source