Xuan Chen,1,* Mingrui Duan,1,2,* Rui Hou,1,2,* Manqi Zheng,1,2 Haibin Li,3 Manjot Singh,4,5 Changwei Li,6 Kuo Liu,1,2 Feng Zhang,1,2 Xinghua Yang,1,2 Yanxia Luo,1,2 Yan He,1,2 Lijuan Wu,1,2 Deqiang Zheng1,2,7 1Department of Epidemiology and ...
Chen X+13 more
doaj
Efficacy and toxicity of bevacizumab in recurrent ovarian disease: an update meta-analysis on phase III trials [PDF]
Background: To analyze the efficacy and toxicity of bevacizumab on survival outcomes in recurrent ovarian cancer. Results: Bevacizumab was associated with significant improvement of PFS and OS compared with standard treatment with HRs of 0.53 (95% CI 0.
BENEDETTI PANICI, PIERLUIGI+9 more
core +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez+17 more
wiley +1 more source
The population of the Venafro Valley (Southern Italy) faces various type of air pollution problems (industrial facilities, traffic, and biomass combustion).
Elisa Bustaffa+5 more
doaj +1 more source
Nutritional epidemiology methods and related statistical challenges and opportunities
The public health importance of nutritional epidemiology research is discussed, along with methodological challenges to obtaining reliable information on dietary approaches to chronic disease prevention.
Ross L. Prentice, Ying Huang
doaj +1 more source
Use of Antihypertensive Agents and Association With Risk of Adverse Outcomes in Chronic Kidney Disease: Focus on Angiotensin-Converting Enzyme Inhibitors and Angiotensin Receptor Blockers. [PDF]
Background Our objective was to determine patterns of antihypertensive agent use by stage of chronic kidney disease (CKD) and to evaluate the association between different classes of antihypertensive agents with nonrenal outcomes, especially in advanced ...
Johansen, Kirsten L+4 more
core
Single‐cell insights into the role of T cells in B‐cell malignancies
Single‐cell technologies have transformed our understanding of T cell–tumor cell interactions in B‐cell malignancies, revealing new T‐cell subsets, functional states, and immune evasion mechanisms. This Review synthesizes these findings, highlighting the roles of T cells in pathogenesis, progression, and therapy response, and underscoring their ...
Laura Llaó‐Cid
wiley +1 more source
Clinicopathological Presentation, Prognosis, and Overall Survival of Primary Extra Nodal Lymphomas
Introduction: Primary extranodal lymphoma (PENL) originates from extranodal organs or tissues. Approximately 25–40% of NHL arise primarily from sites other than lymph nodes.
Pravinkumar Ghongade+3 more
doaj +1 more source
Pediatric Malaria with Respiratory Distress: Prognostic Significance of Point-of-Care Lactate
Respiratory distress (RD) in pediatric malaria portends a grave prognosis. Lactic acidosis is a biomarker of severe disease. We investigated whether lactate, measured at admission using a handheld device among children hospitalized with malaria and RD ...
Catherine Mitran+5 more
doaj +1 more source
NT -pro BNP as a Mediator of the Racial Difference in Incident Atrial Fibrillation and Heart Failure. [PDF]
Background Blacks harbor more cardiovascular risk factors than whites, but experience less atrial fibrillation ( AF ). Conversely, whites may have a lower risk of heart failure ( CHF ).
Alonso, Alvaro+12 more
core