Results 31 to 40 of about 7,521 (213)

Serum HBV RNA correlated with intrahepatic cccDNA more strongly than other HBV markers during peg-interferon treatment

Virology Journal, 2021
Background Serum hepatitis B virus RNA (HBV RNA) has been reported to be a surrogate marker of intrahepatic cccDNA during nucleos(t)ide analogs therapy.
Xiaomei Wang, Xiumei Chi, Ruihong Wu, Hongqin Xu, Xiuzhu Gao, Lei Yu, Longgen Liu, Mingxiang Zhang, Youwen Tan, Junqi Niu, Qinglong Jin   +10 more
doaj   +1 more source

Dynamics of Serum Pregenome RNA in Chronic Hepatitis B Patients Receiving 96-Month Nucleos(t)ide Analog Therapy

Frontiers in Medicine, 2022
BackgroundTissue covalently closed circular DNA (cccDNA) can reflect the activity of HBV replication. However, it is impractical to assess intrahepatic cccDNA in every outpatient.
Yachao Tao, Yachao Tao, Menglan Wang, Menglan Wang, Juan Liao, Juan Liao, Xing Cheng, Xing Cheng, Min He, Min He, Dongmei Zhang, Dongmei Zhang, Taoyou Zhou, Taoyou Zhou, Jie Chen, Enqiang Chen, Enqiang Chen, Hong Tang, Hong Tang   +18 more
doaj   +1 more source

Predictors of HBeAg seroconversion after long-term nucleos(t)ide analogues treatment for chronic hepatitis B: a multicenter study in real clinical setting

Brazilian Journal of Infectious Diseases, 2017
Aims: To evaluate the HBeAg seroconversion rate in real clinical setting and explore its predictors in long-term nucleos(t)ide analogues (NAs) treatment for chronic hepatitis B (CHB).
Weiyan Yu, Yadong Wang, Chuan Shen, Ru Ji, Li Zhang, Xin Zhao, Miao Su, Ying Zhang, Wenyan He, Jianguo Cao, Yanshuang Hao, Shengpeng Chen, Caiyan Zhao   +12 more
doaj   +1 more source

Lamivudine plus adefovir is a good option for chronic hepatitis B patients with viral relapse after cessation of lamivudine treatment [PDF]

, 2011
Aim Currently, there is no consensus on the retreatment recommendation of chronic hepatitis B (CHB) patients with viral rebound after cessation of treatment.
Zhao Wang, Xiao-Ling Wu, Wei-Zheng Zeng, Hui Xu, Yong Zhang, Jian-Ping Qin, Ming-De Jiang   +6 more
core   +2 more sources

Long-term outcome after spontaneous HBeAg seroconversion in patients with chronic hepatitis B [PDF]

Hepatology, 2002
During the course of chronic hepatitis B virus (HBV) infection, hepatitis B e antigen (HBeAg) seroconversion to its antibody (anti-HBe) often coincides with normalization of liver biochemical test and clinical remission, but data regarding long-term outcome after spontaneous seroconversion are still scarce.
Yao-Shih, Hsu, Rong-Nan, Chien, Chau-Ting, Yeh, I-Shyan, Sheen, Hung-Yi, Chiou, Chia-Ming, Chu, Yun-Fan, Liaw   +6 more
openaire   +2 more sources

Lower mutation frequency of BCP/precore regions in e antigen-negative chronic HBV-infected children instead of adults patients.

PLoS ONE, 2015
To describe the Hepatitis B e antigen(HBeAg) seroconversion related mutation profiles of the basal core promoter(BCP)/precore regions in e antigen seroconverted child patients, a cohort of 245 child patients with CHB and a control patients group of 92 ...
Yong Huang, Haijun Deng, Xuefeng Shan, Xuyang Gong, Xiaosong Li, Zen Tu, Quanxin Long, Ailong Huang   +7 more
doaj   +1 more source

A one-year trial of lamivudine for chronic hepatitis B [PDF]

, 1998
Background and Methods: In preliminary trials, lamivudine, an oral nucleoside analogue, has shown promise for the treatment of chronic hepatitis B. We conducted a one-year double-blind trial of lamivudine in 358 Chinese patients with chronic hepatitis B.
Barber, J, Chang, TT, Chien, RN, Dent, JC, Gray, DF, Guan, R, Lai, CL, Leung, NWY, Ng, KY, Stephenson, SL, Tai, DI, Wu, PC   +11 more
core   +1 more source

Hepatitis B surface antigen quantification at hepatitis B e antigen seroconversion predicts virological relapse after the cessation of entecavir treatment in hepatitis B e antigen-positive patients

International Journal of Infectious Diseases, 2016
Objectives: To assess off-treatment virological relapse rates and to determine the role of hepatitis B surface antigen (HBsAg) quantification in predicting virological relapse after stopping entecavir (ETV) treatment in patients with hepatitis B e ...
Yuan-wang Qiu, Li-hua Huang, Wen-long Yang, Zhen Wang, Bo Zhang, Yi-guang Li, Ting-ting Su, Hong-yan Zhou, Wei Xu, Xue-dong Wang, Ya-ping Dai, Jian-he Gan   +11 more
doaj   +1 more source

O-22 DIFFERENTIAL MUTATION PATTERN ASSOCIATED WITH HEPATITIS B E ANTIGEN SEROCONVERSION BETWEEN SUBGENOTYPE F1b CLUSTERS: POTENTIAL ROLE IN PATHOGENESIS

Annals of Hepatology, 2023
Introduction and Objectives: Two clusters of the subgenotype F1b (basal and cosmopolitan) have recently been described. The basal cluster has been associated with the early occurrence of hepatocellular carcinoma in chronically infected patients from ...
Micaela Martínez, Mercedes Elizalde, Micaela Speroni, Rodolfo Campos, Diego Flichman   +4 more
doaj   +1 more source

Relative predictive factors for hepatocellular carcinoma after HBeAg seroconversion in HBV infection

World Journal of Gastroenterology, 2005
To determine the predictive factors for hepatocellular carcinoma (HCC) development in patients after spontaneous or therapeutic HBeAg seroconversion.In 48 patients who seroconverted to anti-HBe positive during follow-up, the background factors for HCC development were analyzed.HCC was developed in six patients during follow-up (average follow-up after ...
Kazumoto, Murata, Kazushi, Sugimoto, Katsuya, Shiraki, Takeshi, Nakano   +3 more
openaire   +2 more sources