Results 71 to 80 of about 136,614 (358)
Clinical Pharmacology in Drug Development, EarlyView.Abstract Votoplam is a novel, orally bioavailable, small molecule HTT gene splicing modifier that is being developed for the treatment of Huntington's disease. This was a single dose, open‐label, two‐period, crossover food effect study that evaluated the effect of high‐ and low‐fat meals on 20 mg votoplam in healthy participants. There was a washout of
Lucy Lee +5 more
wiley +1 more source
Early Dynamics of Hepatitis B Virus (HBV)-DNA and Surface Antigen (HBsAg) in Ramp-Up Phase of Viremia: Implications for Performance Evaluation of Blood Screening Assays [PDF]
, 2022 Harry van Drimmelen, Nico Lelie
openalex +1 more source
Scientific Reports, 2017 Patients with low hepatitis B surface antigen (HBsAg) levels and hepatitis B virus (HBV) DNA suppression by nucleos(t)ide analogues (NAs) achieve high rate of HBsAg loss through switching to PegIFNα in pre-registration study. The aim of this study was to
Jing Huang +5 more
semanticscholar +1 more source
Recent advances in the treatment of chronic hepatitis B: where to start initial therapy?
Журнал инфектологии, 2014 This review summarizes recent advances in the study of the efficacy and safety of antiviral therapy in patients with chronic hepatitis B. Describe the modern concept of monitoring and treatment of these patients.
K. V. Zhdanov
doaj +1 more source
Effect of HIV infection and antiretroviral therapy on hepatitis B virus (HBV)-specific T cell responses in patients who have resolved HBV infection [PDF]
, 2005 Coinfection with hepatitis B virus (HBV) is a common occurrence in human immunodeficiency virus (HIV)–positive patients and an increasing cause of morbidity and mortality.
Bertoletti, A. +9 more
core +1 more source
Analysis of the HBsAg status of toddlers born to HbsAg-reactive mothers at the Sikumana Community Health Center, Kupang City, in 2021 [PDF]
, 2022 Rosina Kardina Kidi Hurek +2 more
openalex +1 more source
International Journal of Cancer, EarlyView.What's New? Disruption of the gut–liver axis has been suggested to play an important role in liver carcinogenesis. However, limited prospective research has explored associations between potentially harmful gut‐derived bacterial products and liver cancer risk.
Cody Z. Watling +36 more
wiley +1 more source
International Journal of General Medicine, 2020 Alemayehu Sayih Belay,1 Dejene Derseh Abateneh,1,2 Sisay Shewasinad Yehualashet,1,3 Kindie Mitiku Kebede1 1Mizan Tepi University, College of Health Sciences, Mizan Aman, Ethiopia; 2Kotebe Metropolitan University, Menelik II College of Medicine and Health
Belay AS +3 more
doaj
Pharmaceutical Biology, 2019 Context: The co-delivery of adjuvant and antigen has shown to be more effective for targeting the immune response than antigen alone. Therefore, designing an efficient bicistronic system is more assuring for production of both elements in the same ...
Sara Mohammadzadeh +3 more
doaj +1 more source
Журнал инфектологии, 2014 Presented clinical case describes elimination followed by seroconversion HBsAg / HBsAb patient with HBeAg-negative chronic hepatitis B on antiviral therapy with pegylated interferon α2-a and achieving sustained virological response.
K. V. Zhdanov +7 more
doaj +1 more source