Results 21 to 30 of about 780 (113)
Virological factors associated with hepatitis B virus reactivation (HBV-R), following chemotherapy for cancer in hepatitis B surface antigen (HBsAg)-negative patients, are not well known.HBV strains from 16 patients presenting HBV-R following chemotherapy were studied and compared to those obtained from 51 HBV chronically-infected patients.HBsAg ...
Colson, Philippe +15 more
openaire +2 more sources
Mechanisms downstream of reverse transcription reduce serum levels of HBV DNA but not of HBsAg in chronic hepatitis B virus infection [PDF]
Hepatitis B virus (HBV) DNA in serum of chronically infected patients declines by 3-4 log10 units at loss of HBe antigen (HBeAg) from serum. The mechanisms behind this decline, and the much smaller decline of surface antigen (HBsAg) levels, are still not well known.
Larsson, Simon B. +4 more
openaire +2 more sources
Hepatitis B virus (HBV) reactivation has been noted in HBV surface antigen (HBsAg)-seronegative patients with CD20 B-cell non-Hodgkin lymphoma (NHL) undergoing rituximab treatment. Clinically, hepatitis flares are usually associated with the reappearance of HBsAg (reverse seroconversion of HBsAg, HBV-RS). It is unclear whether human genetic factors are
Hsiao, Liang-Tsai +13 more
openaire +3 more sources
Guichan Liao,1,2 Xia Ding,1,2 Muye Xia,1,2 Yin Wu,1– 3 Hongjie Chen,1,2 Rong Fan,1,2 Xiaoyong Zhang,1,2 Shaohang Cai,1,2 Jie Peng1,2 1Department of Infectious Diseases, Nanfang Hospital, Southern Medical University, Guangzhou, People’s Republic of China;
Liao G +8 more
doaj
In Argentina, current procedures to ensure the safety of the blood supply for transfusion include the serologic detection of specific blood-borne infections. The aim of this study was to evaluate the prevalence and the genetic diversity of hepatitis B virus (HBV) and hepatitis D virus (HDV) in blood donor populations from two distantly located ...
Delfino, Cecilia María +13 more
openaire +3 more sources
Abstract Background Currently, pegylated interferon-α (Peg-IFN-α)-based antiviral therapy brings dawn to the clinical cure of chronic hepatitis B(CHB). Our aim was to investigate markers associated with clinical cure and off-treatment hepatitis B surface antigen (HBsAg) reversion in CHB receiving Peg-IFN-α-based therapy. Methods In total, 101
Zhongwei Liu +9 more
openaire +1 more source
In 59,946 chronic hepatitis B patients followed over 23 years, COVID‐19 vaccination rollout was temporally associated with a 56% increase in HBsAg loss rates (peak 1.27 per 100 person‐years in 2022), followed by gradual waning. Negative control outcomes showed no similar pattern, supporting biological specificity. ABSTRACT Background and Aims Hepatitis
Jonggi Choi +6 more
wiley +1 more source
The mechanism underlying the coexistence of hepatitis B surface antigen and antibodies to HBsAg in chronic hepatitis B patients remains unknown.This research aimed to determine the clinical and virological features of the rare pattern.A total of 32 chronic hepatitis B patients infected by HBV genotype C were included: 15 carrying both HBsAg and anti ...
Ding, Feng +4 more
openaire +5 more sources
ABSTRACT Hepatitis delta virus (HDV) infection causes chronic hepatitis D (CHD), the most severe form of chronic viral hepatitis with a high risk of progression to advanced liver disease. Off‐label pegylated interferon alpha was the primary treatment option in Europe prior to the introduction of bulevirtide, a first‐in‐class HDV entry inhibitor.
Monica Radu +11 more
wiley +1 more source
In a population‐based cohort in Japan, HBV reactivation‐related events were observed after HBsAg seroclearance, including one virologically confirmed hepatic flare occurring spontaneously without chemotherapy or immunosuppression. These findings indicate that HBsAg seroclearance does not always represent complete viral eradication, supporting the need ...
Kazumi Yamasaki +7 more
wiley +1 more source

