Results 31 to 40 of about 780 (113)
Hepatitis B virus (HBV) subgenotype B2 is prevalent in China and some other parts of Asia. This study aimed to carry out a subgenotype B2 specific mutation analysis on important amino acid (AA) sites in overlapping reverse transcriptase (RT) and surface (S) protein coding regions of HBV.A total of 143 hepatitis B e antigen (HBeAg)-positive chronic ...
Mingze Su +8 more
openaire +2 more sources
Abstract Cryoglobulinemia (CG) is defined by the presence of serum immunoglobulins that precipitate below 37°C and redissolve upon rewarming. It is classified into three types based on immunoglobulin composition. Type I, a rare form, involves monoclonal IgM or IgG and is linked to lymphoproliferative disorders.
Anna Linda Zignego +7 more
wiley +1 more source
Background Psoriasis vulgaris is a chronic immune‐mediated inflammatory disease frequently requiring long‐term biologic therapy. Although biologics targeting TNF‐α and interleukin pathways have revolutionized disease management, they may disrupt antiviral immune surveillance and trigger hepatitis B virus (HBV) reactivation in individuals with prior HBV
Neslihan Demirel Öğüt +7 more
wiley +1 more source
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro +5 more
wiley +1 more source
An N‐glycosylation was strategically introduced at the 166th position of VP1 via artificial mutagenesis. The glycans mainly consist of high‐mannose type, significantly enhancing the stability and uptake of VLPs. The glycosylated VLPs conferred a robust Th1‐type immune response in mice and pigs and provided 100% protection against FMDV in pigs ...
Zhiyao Li +10 more
wiley +1 more source
From Lab to Market: Paper‐Based CRISPR Diagnostics and Commercialization Pathways
Paper‐based CRISPR diagnostics represents one of the most widely commercialized CRISPR assay technologies, yet challenges remain for broader point‐of‐care use. Abstract The global health landscape is continually challenged by infectious diseases that can swiftly escalate into pandemics, underscoring the need for rapid, accurate, and cost‐effective ...
Selen Dalgan, Qingshan Wei
wiley +1 more source
Reversed passive hemagglutination test fails to detect HBsAg in a number of HBeAg positive sera.
In endemic areas of hepatitis B virus (HBV) infection, perinatal transmission from asymptomatic HBsAg carrier mothers to infants plays a major role in the transmission of HBV. HBeAg indicates a high level of viral replication and infectivity. Most of the infants born to HBeAg positive mothers become carriers.
Duangtawan, Thammanichanond +3 more
openaire +1 more source
ABSTRACT Hepatitis B virus (HBV) infection is a global health challenge, with the World Health Organization (WHO) targeting its elimination by 2030. Jordan lacks sufficient data on HBV epidemiology, including prevalence, incidence and clearance. This study addresses these gaps through a retrospective analysis of HBV testing data from 40,268 individuals
Issa Abu‐Dayyeh +6 more
wiley +1 more source
Liver Involvement in Celiac Disease and Immune‐Mediated Diseases of the Small Bowel
ABSTRACT Disorders of the hepatobiliary system are commonly associated with gastrointestinal (GI) diseases. The GI and hepatobiliary systems interact through the portal vein system and enterohepatic circulation, creating a gut–liver axis that allows for a complex multidirectional interplay between immune, hormonal, dietary and environmental luminal ...
Nicoletta Nandi +8 more
wiley +1 more source
ABSTRACT Transplantation is one of the few life‐saving therapies for patients with end‐stage organ disease, yet organ availability remains restrictive. Expanding donors to include those with hepatitis B virus (HBV) infection, incorporating HBV nucleic acid amplification testing (NAT) positive donors, could improve organ access.
Patrick C. K. Tam +7 more
wiley +1 more source

