Results 1 to 10 of about 2,204,237 (310)

CRISPR/Cas13a-assisted rapid and portable HBV DNA detection for low-level viremia patients. [PDF]

Emerg Microbes Infect, 2023
Background & Aims The WHO declared to eliminate hepatitis B virus (HBV) by 2030. However, an increasing number of patients are presenting with low-level viremia (LLV) with the widespread use of antiviral medications.
Tian Y, Fan Z, Xu L, Cao Y, Chen S, Pan Z, Gao Y, Li H, Zheng S, Ma Y, Duan Z, Zhang X, Ren F.   +12 more
europepmc   +2 more sources

Exosomal HBV-DNA for diagnosis and treatment monitoring of chronic hepatitis B [PDF]

Open Life Sciences, 2023
This study examined exosomal hepatitis B virus (HBV)-DNA levels in chronic HBV infection (CHB). Patients were grouped according to the European Association for the Study of the Liver classification (1: HBV-DNA-positive CHB, normal alanine ...
Xu Xu, Zhang Li, Liu Jiamin, Kong Xiangxin, Yin Yu, Jia Zhiwei, Zhang Xiaoqin, Peng Bin, Ji Min, Pan Wanlong   +9 more
doaj   +2 more sources

The E3 Ubiquitin Ligase TRIM21 Promotes HBV DNA Polymerase Degradation

Viruses, 2020
The tripartite motif (TRIM) protein family is an E3 ubiquitin ligase family. Recent reports have indicated that some TRIM proteins have antiviral functions, especially against retroviruses.
Ting Mu, Xiaoqing Zhao, Yanan Zhu, Hongxia Fan, Hua Tang   +4 more
doaj   +2 more sources

HBV DNA polymerase regulates tumor cell glycogen to enhance the malignancy of HCC cells [PDF]

Hepatology Communications
Background:. The essential function of HBV DNA polymerase (HBV-DNA-Pol) is to initiate viral replication by reverse transcription; however, the role of HBV-DNA-Pol in HBV-associated HCC has not been clarified.
Xiaoqing Zhao, Chunqing Wang, Liqing Zhao, Zhongzheng Tian   +3 more
doaj   +2 more sources

Association between high HBV-DNA viral load and liver metastasis risk in patients with nasopharyngeal carcinoma [PDF]

Virus Research
A total of 976 patients with nasopharyngeal carcinoma (NPC) confirmed by pathology in Xiangya Cancer Hospital of Central South University from May 2017 to December 2022 were recruited for the study.
Xiaofan Wang, Ying Bao, Sheng Yin, Yizhi Peng   +3 more
doaj   +2 more sources

Coexisting patterns and significance of serum HBV RNA and HBV DNA in patients with treatment-naïve chronic hepatitis B virus infection [PDF]

Frontiers in Medicine
AimThe study aimed to explore the coexisting patterns and assess the significance of serum hepatitis B virus (HBV) RNA and traditional virological biomarkers in patients with antiviral treatment-naïve chronic hepatitis B virus (HBV) infection ...
Kun-yan Hao, Kun-yan Hao, Ye Fan, Yi-qing Zhang, Yue-cheng Yu   +4 more
doaj   +2 more sources

Lower HBV DNA level is associated with more severe liver fibrosis in HBeAg-positive chronic hepatitis B with normal alanine transaminase [PDF]

Virology Journal
Background The association of hepatitis B virus (HBV) DNA levels and liver fibrosis in chronic hepatitis B (CHB) patients with immune-tolerant phase remains unclear.
Jian Wang, Li Zhu, Zhiyi Zhang, Shaoqiu Zhang, Yifan Pan, Yuanyuan Li, Fei Cao, Chao Jiang, Tao Fan, Ye Xiong, Jiacheng Liu, Yuxin Chen, Shengxia Yin, Xin Tong, Chuanwu Zhu, Xingxiang Liu, Jie Li, Chao Wu, Rui Huang   +18 more
doaj   +2 more sources

HBV DNA polymerase upregulates the transcription of PD-L1 and suppresses T cell activity in hepatocellular carcinoma [PDF]

Journal of Translational Medicine
Background In HBV-associated HCC, T cells often exhibit a state of functional exhaustion, which prevents the immune response from rejecting the tumor and allows HCC to progress.
Yan Jia, Jianing Zhao, Chunqing Wang, Jing Meng, Liqing Zhao, Hongwei Yang, Xiaoqing Zhao   +6 more
doaj   +2 more sources

Rapid quantification assay of hepatitis B virus DNA in human serum and plasma by Fully Automated Genetic Analyzer μTASWako g1.

PLoS ONE, 2023
Real-time monitoring of serum hepatitis B virus (HBV) levels is essential for the management of patients with chronic HBV infection in clinical practice, including monitoring the resistance of anti-HBV nucleotide analog or the detection of HBV ...
Moto Watanabe, Hidenori Toyoda, Tomohisa Kawabata   +2 more
doaj   +2 more sources

Comparison of HBV-DNA Levels with Biochemical and Microbiological Parameters for Chronic Hepatitis Evaluation, Bursa, Turkey [PDF]

Journal of Medical Microbiology and Infectious Diseases, 2021
Introduction: HBV-DNA levels are used to diagnose chronic hepatitis B (CHB) disease, determine the infection phase, decide on the treatment, and determine the disease course.
Sanem Karadag Gecgel
doaj   +2 more sources