Results 11 to 20 of about 2,442,539 (329)

CRISPR/Cas13a-assisted rapid and portable HBV DNA detection for low-level viremia patients [PDF]

Emerging Microbes and Infections, 2023
Background & Aims The WHO declared to eliminate hepatitis B virus (HBV) by 2030. However, an increasing number of patients are presenting with low-level viremia (LLV) with the widespread use of antiviral medications.
Tian Y, Fan Z, Xu L, Cao Y, Chen S, Pan Z, Gao Y, Li H, Zheng S, Ma Y, Duan Z, Zhang X, Ren F.   +12 more
exaly   +3 more sources

HBV DNA polymerase upregulates the transcription of PD-L1 and suppresses T cell activity in hepatocellular carcinoma [PDF]

Journal of Translational Medicine
Background In HBV-associated HCC, T cells often exhibit a state of functional exhaustion, which prevents the immune response from rejecting the tumor and allows HCC to progress.
Yan Jia, Jianing Zhao, Chunqing Wang, Jing Meng, Liqing Zhao, Hongwei Yang, Xiaoqing Zhao   +6 more
doaj   +2 more sources

Rapid quantification assay of hepatitis B virus DNA in human serum and plasma by Fully Automated Genetic Analyzer μTASWako g1.

PLoS ONE, 2023
Real-time monitoring of serum hepatitis B virus (HBV) levels is essential for the management of patients with chronic HBV infection in clinical practice, including monitoring the resistance of anti-HBV nucleotide analog or the detection of HBV ...
Moto Watanabe, Hidenori Toyoda, Tomohisa Kawabata   +2 more
doaj   +2 more sources

Comparison of HBV-DNA Levels with Biochemical and Microbiological Parameters for Chronic Hepatitis Evaluation, Bursa, Turkey [PDF]

Journal of Medical Microbiology and Infectious Diseases, 2021
Introduction: HBV-DNA levels are used to diagnose chronic hepatitis B (CHB) disease, determine the infection phase, decide on the treatment, and determine the disease course.
Sanem Karadag Gecgel
doaj   +2 more sources

Ubiquitous expression of HBsAg from integrated HBV DNA in patients with low viral load.

Journal of Hepatology, 2021
BACKGROUND & AIMS Loss of serum hepatitis B surface antigen (HBsAg) is a hallmark of spontaneous and therapy induced resolution of HBV infection, since it generally reflects a profound decrease in viral replication.
Marie-Anne Meier, D. Calabrese, A. Suslov, L. Terracciano, M. Heim, S. Wieland   +5 more
semanticscholar   +1 more source

Presence of Liver Inflammation in Asian Patients With Chronic Hepatitis B With Normal ALT and Detectable HBV DNA in Absence of Liver Fibrosis

Hepatology Communications, 2021
Liver biopsies are recommended to exclude significant liver inflammation in patients with chronic hepatitis B (CHB) with elevated HBV DNA but without other indications for antiviral treatment.
Jiacheng Liu, Jian Wang, Xiaomin Yan, Ruifei Xue, Jie Zhan, Su-Yu Jiang, Yu Geng, Yilin Liu, Minxin Mao, J. Xia, Shengxia Yin, Xin Tong, Yuxin Chen, Weimao Ding, Rui Huang, Chao Wu   +15 more
semanticscholar   +1 more source

Signature of chronic hepatitis B virus infection in nails and hair

BMC Infectious Diseases, 2022
Background Hepatitis B virus (HBV) is detected in extrahepatic tissues of individuals with HBV infection. Whether nails and hair contain HBV has been unknown.
Haruki Komatsu, Ayano Inui, Enkhtaivan Odmaa, Yoshinori Ito, Hiroki Hoshino, Shuichiro Umetsu, Tomoyuki Tsunoda, Tomoo Fujisawa   +7 more
doaj   +1 more source

Mitochondrial DNA is a target of HBV integration

Communications Biology, 2023
Abstract Hepatitis B virus (HBV) may integrate into the genome of infected cells and contribute to hepatocarcinogenesis. However, the role of HBV integration in hepatocellular carcinoma (HCC) development remains unclear.
Giosa, Domenico, Lombardo, Daniele, Musolino, Cristina, Chines, Valeria, Raffa, Giuseppina, Casuscelli di Tocco, Francesca, D'Aliberti, Deborah, Caminiti, Giuseppe, Saitta, Carlo, Alibrandi, Angela, Aiese Cigliano, Riccardo, Romeo, Orazio, Navarra, Giuseppe, Raimondo, Giovanni, Pollicino, Teresa   +14 more
openaire   +3 more sources

Hepatitis B virus infection in human immunodeficiency virus infected southern African adults: occult or overt--that is the question. [PDF]

PLoS ONE, 2012
Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) share transmission routes and are endemic in sub-Saharan Africa. The objective of the present study was to use the Taormina definition of occult HBV infection, together with stringent ...
Trevor G Bell, Euphodia Makondo, Neil A Martinson, Anna Kramvis   +3 more
doaj   +1 more source

HBV DNA Level Finding [PDF]

Definitions, 2020
openaire   +2 more sources