Prospective comparison of Abbott RealTime HBV DNA and Versant HBV DNA 3.0 assays for hepatitis B DNA quantitation: Impact on HBV genotype monitoring [PDF]
Journal of Virological Methods, 2008 The quantitation of human hepatitis B virus (HBV) in the serum of infected patients is recommended to characterize the course of chronic HBV infection. The aim of this prospective study was to evaluate the performance of the Abbott RealTime PCR assay for HBV DNA quantitation by comparison with the standard Versant HBV DNA 3.0 assay.
Pol, Jonathan +12 more
openaire +3 more sources
HBV‐RNA Co‐amplification May Influence HBV DNA Viral Load Determination [PDF]
Hepatology Communications, 2020 Despite effective hepatitis B virus (HBV)‐DNA suppression, HBV RNA can circulate in patients receiving nucleoside/nucleotide analogues (NAs). Current assays quantify HBV DNA by either real‐time polymerase chain reaction (PCR), which uses DNA polymerase ...
Benjamin Maasoumy +12 more
doaj +2 more sources
Zhongguo shuxue zazhi, 2022 Objective To investigate the serological and molecular characteristics of HBsAg+ /HBV DNA non-reactive (NR) infections. Methods Samples tested as HBsAg+ and HBV DNA NR were confirmed by individual NAT repeat testing, viral particle concentration by PEG ...
Chunxiang LI +8 more
doaj +2 more sources
The Infection Efficiency and Replication Ability of Circularized HBV DNA Optimized the Linear HBV DNA in Vitro and in Vivo [PDF]
International Journal of Molecular Sciences, 2015 Studies on molecular mechanisms of the persist infection of hepatitis B virus have been hampered by a lack of a robust animal model. We successfully established a simple, versatile, and reproducible HBV persist infection model in vitro and in vivo with the circularized HBV DNA. The cells and mice were transfected or injected with circularized HBV DNA
Xiaosong Li +7 more
openaire +3 more sources
HBV DNA polymerase upregulates the transcription of PD-L1 and suppresses T cell activity in hepatocellular carcinoma [PDF]
Journal of Translational MedicineBackground In HBV-associated HCC, T cells often exhibit a state of functional exhaustion, which prevents the immune response from rejecting the tumor and allows HCC to progress.
Yan Jia +6 more
doaj +2 more sources
产妇血清HBV DNA含量对乳汁和新生儿血清HBV DNA浓度的影响
Zhongshan Daxue xuebao. Yixue kexue ban, 2010 【目的】 探讨乙型肝炎病毒携带产妇血清HBV DNA含量对乳汁和新生儿血清中HBV DNA含量的影响,以指导孕期处理和母乳喂养。【方法】 选择乙型肝炎病毒携带产妇145例,采用荧光定量聚合酶链反应(FQ-PCR)技术对产妇血清，母乳和新生儿血清HBV DNA进行检测,并将产妇血清HBV DNA浓度分3级,分析产妇血清不同HBV DNA浓度级对乳汁及新生儿血清HBV DNA浓度的影响。【结果】 血清HBV DNA < 500 copies/mL的产妇74例,乳汁中检出HBV DNA阳性为零 ...
doaj +1 more source
PLoS ONE, 2023 Real-time monitoring of serum hepatitis B virus (HBV) levels is essential for the management of patients with chronic HBV infection in clinical practice, including monitoring the resistance of anti-HBV nucleotide analog or the detection of HBV ...
Moto Watanabe +2 more
doaj +2 more sources
Comparison of HBV-DNA Levels with Biochemical and Microbiological Parameters for Chronic Hepatitis Evaluation, Bursa, Turkey [PDF]
Journal of Medical Microbiology and Infectious Diseases, 2021 Introduction: HBV-DNA levels are used to diagnose chronic hepatitis B (CHB) disease, determine the infection phase, decide on the treatment, and determine the disease course.
Sanem Karadag Gecgel
doaj +2 more sources
CRISPR/Cas13a-assisted rapid and portable HBV DNA detection for low-level viremia patients [PDF]
Emerging Microbes and Infections, 2023 Zhenzhen Pan
exaly +2 more sources
Signature of chronic hepatitis B virus infection in nails and hair
BMC Infectious Diseases, 2022 Background Hepatitis B virus (HBV) is detected in extrahepatic tissues of individuals with HBV infection. Whether nails and hair contain HBV has been unknown.
Haruki Komatsu +7 more
doaj +1 more source