Detection of HBV DNA integration in plasma cell-free DNA of different HBV diseases utilizing DNA capture strategy [PDF]
Virologica SinicaThe landscape of hepatitis B virus (HBV) integration in the plasma cell-free DNA (cfDNA) of HBV-infected patients with different stages of liver diseases [chronic hepatitis B (CHB), liver cirrhosis (LC), and hepatocellular carcinoma (HCC)] remains unclear.
Hongchun Luo +2 more
exaly +4 more sources
Exosomal HBV-DNA for diagnosis and treatment monitoring of chronic hepatitis B [PDF]
Open Life Sciences, 2023 This study examined exosomal hepatitis B virus (HBV)-DNA levels in chronic HBV infection (CHB). Patients were grouped according to the European Association for the Study of the Liver classification (1: HBV-DNA-positive CHB, normal alanine ...
Xu Xu +9 more
doaj +2 more sources
The Role of Integrated HBV DNA in the Quest for a Cure in HIV/HBV co-infection. [PDF]
Curr HIV/AIDS RepThis review highlights the importance of Hepatitis B virus (HBV) integrated into the host genome (iDNA) to functional cure and how human immunodeficiency virus (HIV) may affect HBV integration.Functional cure of chronic hepatitis B infection is characterized by durable loss of hepatitis B surface antigen (HBsAg) from blood after treatment ...
Mani M, Thio CL, Balagopal A.
europepmc +4 more sources
Association between HBV DNA levels and bone mineral density in antiviral-naive chronic hepatitis B patients [PDF]
Frontiers in EndocrinologyObjectivesRecent studies have shown that patients with chronic hepatitis B (CHB) have an increased prevalence of osteoporosis. However, the direct relationship between hepatitis B virus (HBV) DNA (representing the viral replication level) and bone ...
Xinyu Zhou +5 more
doaj +2 more sources
HBV DNA polymerase regulates tumor cell glycogen to enhance the malignancy of HCC cells [PDF]
Hepatology CommunicationsBackground:. The essential function of HBV DNA polymerase (HBV-DNA-Pol) is to initiate viral replication by reverse transcription; however, the role of HBV-DNA-Pol in HBV-associated HCC has not been clarified.
Xiaoqing Zhao +3 more
doaj +2 more sources
Association between high HBV-DNA viral load and liver metastasis risk in patients with nasopharyngeal carcinoma [PDF]
Virus ResearchA total of 976 patients with nasopharyngeal carcinoma (NPC) confirmed by pathology in Xiangya Cancer Hospital of Central South University from May 2017 to December 2022 were recruited for the study.
Xiaofan Wang +3 more
doaj +2 more sources
Comparison of novel DiaRD-HBV DNA qPCR kit with the <i>artus</i> HBV QS-RGQ kit for quantification of HBV DNA in clinical samples. [PDF]
Turk J Med SciHepatitis B virus (HBV) leads to widespread chronic infections that may result in long-term complications such as cirrhosis and hepatocellular carcinoma. The use of sensitive molecular methods for HBV DNA quantitation has provided significant contributions for diagnosis and monitoring of disease.
Çuhaci Ü +4 more
europepmc +4 more sources
The E3 Ubiquitin Ligase TRIM21 Promotes HBV DNA Polymerase Degradation
Viruses, 2020 The tripartite motif (TRIM) protein family is an E3 ubiquitin ligase family. Recent reports have indicated that some TRIM proteins have antiviral functions, especially against retroviruses.
Ting Mu +4 more
doaj +3 more sources
Coexisting patterns and significance of serum HBV RNA and HBV DNA in patients with treatment-naïve chronic hepatitis B virus infection [PDF]
Frontiers in MedicineAimThe study aimed to explore the coexisting patterns and assess the significance of serum hepatitis B virus (HBV) RNA and traditional virological biomarkers in patients with antiviral treatment-naïve chronic hepatitis B virus (HBV) infection ...
Kun-yan Hao +4 more
doaj +2 more sources
Lower HBV DNA level is associated with more severe liver fibrosis in HBeAg-positive chronic hepatitis B with normal alanine transaminase [PDF]
Virology JournalBackground The association of hepatitis B virus (HBV) DNA levels and liver fibrosis in chronic hepatitis B (CHB) patients with immune-tolerant phase remains unclear.
Jian Wang +18 more
doaj +2 more sources