Results 131 to 140 of about 2,204,237 (310)

Potential mutations associated with occult hepatitis B virus status [PDF]

, 2014
Context: Occult hepatitis B virus (HBV) status (OHBS) is simply defined as the presence of HBV DNA in the liver (with or without detectable HBV DNA in the serum), in the absence of serum HBV surface antigen (HBsAg). Importance of OHBS is mostly clinical,
Besharat, S., Katoonizadeh, A., Moradi, A.   +2 more
core   +1 more source

Disease Progression Mathematical Modeling With a Case Study on Hepatitis B Virus Infection

CPT: Pharmacometrics &Systems Pharmacology, Volume 14, Issue 3, Page 420-434, March 2025.
ABSTRACT Chronic Hepatitis B presents a significant health and socioeconomic burden. The risk of hepatocellular carcinoma remains elevated although treatments are available. Achieving an optimal treatment regimen necessitates a deep comprehension of the dynamic relationship between the virus and its host across disease states.
Clémence Boivin‐Champeaux, Nieves Velez de Mendizabal, Aksana Jones, Scott Balsitis, Stephan Schmidt, Justin S. Feigelman, Francine Johansson Azeredo   +6 more
wiley   +1 more source

Hepatitis B serological markers and plasma DNA concentrations. [PDF]

, 2017
OBJECTIVES: To examine hepatitis B (HBV) serological markers and plasma DNA concentrations in a large group of untreated HBV/HIV-coinfected individuals in two sub-Saharan settings. DESIGN: Baseline analysis of a randomized controlled trial. METHODS: DART
Chirara, Michael, DART Virology Group, Dunn, David, Gilks, Charles, Gilson, Richard, Hakim, James, Kaleebu, Pontiano, Kityo, Cissy, Munderi, Paula, Pillay, Deenan, Price, Huw, Spyer, Moira, Vudriko, Tobias, Zachary, Tamale   +13 more
core   +2 more sources

Nature Inspired Delivery Vehicles for CRISPR‐Based Genome Editing

Small, EarlyView.
The review highlights nature‐inspired nanocarriers for CRISPR delivery, emphasizing viral vectors, extracellular vesicles, liposomes, and lipid nanoparticles. It discusses their roles in improving specificity, minimizing immunogenicity, and overcoming barriers in genome editing. Recent advancements, challenges, and therapeutic applications are explored,
Elizabeth Maria Clarissa, Mamata Karmacharya, Hyunmin Choi, Sumit Kumar, Yoon‐Kyoung Cho   +4 more
wiley   +1 more source

HBV Infection in Human Hepatocytes and Quantification of Encapsidated HBV DNA

BIO-PROTOCOL, 2016
Human hepatic cancer cell lines such as HepG2, Huh7, and HLE cannot get infected with Hepatitis B virus (HBV) due to lack of an HBV receptor(s). Transfection with HBV genome has so far been referred as a tool to mimic HBV infection. However, since sodium taurocholate cotransporting polypeptide (NTCP) was identified as a functional receptor for HBV (Yan
Kai Li, Seiichi Sato, Akinori Takaoka
openaire   +2 more sources

Very Early‐Stage Detection Is Associated With Improved Survival in Patients With Unifocal Hepatocellular Carcinoma

Alimentary Pharmacology &Therapeutics, EarlyView.
In a multicentre cohort of patients with unifocal HCC, patients with very early stage disease had a survival advantage over patients diagnosed at an early stage. Factors associated with mortality included worse liver function, larger tumour size and higher AFP levels.
Thomas Hunold, Karim Seif El Dahan, Suraj Pai, Amit G. Singal, Neehar D. Parikh   +4 more
wiley   +1 more source

The hepatitis B virus reactivation after transarterial chemoembolization in Chinese hepatocellular carcinoma patients with low serum hepatitis B virus DNA level

Therapeutics and Clinical Risk Management, 2015
Wenbo Shao, Fengjuan Zhang, Ning Cong, Jinpeng Li, Jinlong SongDepartment of Surgical Oncology (Interventional Therapy), Shandong Cancer Hospital and Institute, Shandong Academy of Medical Sciences, Jinan, People’s Republic of ChinaObjective ...
Shao W, Zhang F, Cong N, Li J, Song J
doaj  

Indocyanine Green Clearance Correlates With Biomarkers Reflecting Key Disease‐Driving Mechanisms in Advanced Chronic Liver Disease and Predicts Acute‐on‐Chronic Liver Failure and Death

Alimentary Pharmacology &Therapeutics, EarlyView.
Indocyanine green clearance by pulse dye densitometry correlates with portal hypertension, systemic inflammation and circulatory dysfunction in advanced chronic liver disease. While diagnostic accuracy for CSPH was limited, ICG‐R15 independently predicted decompensation and ACLF/liver‐related mortality, highlighting its prognostic value across disease ...
Mathias Jachs, Tânia Carvalho, Benedikt Simbrunner, Georg Semmler, Lukas Hartl, Lorenz Balcar, Benedikt Silvester Hofer, Paul Thöne, Nina Dominik, Georg Kramer, Christian Sebesta, Michael Schwarz, David Bauer, Albert F. Stättermayer, Matthias Pinter, Michael Trauner, Thomas Reiberger, Mattias Mandorfer   +17 more
wiley   +1 more source

HBV RNA at 6 months after nucleos(t)ide analogues treatment can predict antiviral efficacy in chronic hepatitis B patients

BMC Gastroenterology
Background This multicenter study evaluated serum HBV RNA as a prognostic biomarker for nucleos(t)ide analogue (NA) therapy in chronic hepatitis B (CHB), focusing on correlations with HBV DNA/HBsAg and predictive value for virological response (VR) and ...
Yandi Xie, Xiaojing Zhang, Xiaozhou Yang, Sujun Zheng, Shuyun Zhang, Xiaoying Zhang, Haiyan Kang, Xuefei Duan, Wenpin Cai, Peng Yin, Xinghuan Ma, Juan liu, Fengmin Lu, Lizhong Dai, Bo Feng   +14 more
doaj   +1 more source

Seroprevalence Of Hepatitis-b Virus In Mid And Far Western Region In Nepal [PDF]

, 2012
Hepatitis B is significant health problems that might involve the late sequel of liver cirrhosis and hepatocellular carcinoma. The present study aimed to know the seroprevalence of hepatitis B virus (HBV) in mid and far western region in Nepal with ...
H, S. A. (Siddiqui), M, A. (Ansari), P, S. (Singh), S, K. (Khan)   +3 more
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