Results 141 to 150 of about 2,204,237 (310)

Hepatitis B Virus RNA Predicts Hepatocellular Carcinoma Despite Viral Suppression

Alimentary Pharmacology &Therapeutics, EarlyView.
Serum HBV RNA levels at viral suppression predict HCC development in nucleos(t)ide analogue‐treated patients with chronic hepatitis B, outperforming Hepatitis B core‐related antigen alone. ABSTRACT Background Despite achieving undetectable hepatitis B virus (HBV) DNA levels with nucleos(t)ide analogue (NA) therapy, patients with chronic hepatitis B ...
Takashi Kumada, Hidenori Toyoda, Satoshi Yasuda, Yuichi Koshiyama, Takanori Ito, Tomoyuki Akita, Junko Tanaka   +6 more
wiley   +1 more source

孕妇血、脐血、乳汁的乙型肝炎病毒DNA水平及其相关性

Zhongshan Daxue xuebao. Yixue kexue ban, 2000
【目的】探讨乙型肝炎病毒(HBV)母婴垂直传播的规律, 为预防和阻断HBV 的母婴传播提供依据。【方法】对68 例HBsAg 阳性孕产妇以荧光定量PCR方法检测其静脉血、脐血、乳汁HBV DNA 含量并分析其相关性。【结果】孕妇血与脐血 HBV DNA 的含量相关系数为0.3446(P =0.008), 孕妇血与乳汁HBV DNA 的含量的相关系数为0.1449(P =0.261)。【结论】 孕妇血HBV DNA 水平与脐血HBV DNA 水平呈正相关, 降低孕妇血HBV DNA 水平 ...
李小毛, 刘穗玲, 李　霞, 黄怀筠, 卢建溪, 高志良   +5 more
doaj  

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

HCC-derived SNU cell lines as model systems to study HBV life cycle

Journal of Virology
Human SNU cell lines, derived from hepatocellular carcinomas associated with chronic hepatitis B virus (HBV) infection, were examined. The analysis of intracellular RNA and DNA markers of HBV replication and examination of HBV RNA readss coverage of ...
Igor Zaiets, Oleksandra Chazova, Sumedha Gunewardena, Severin O. Gudima   +3 more
doaj   +1 more source

A new group of hepadnaviruses naturally infecting Orangutans (Pongo pygmaeus) [PDF]

, 1999
A high prevalence (42.6%) of hepatitis B virus (HBV) infection was suspected in 195 formerly captive orangutans due to a large number of serum samples which cross-reacted with human HBV antigens.
Heeney, J.L., Heriyanto,, Swan, R.A., Verschoor, E.J., Warren, K.S.   +4 more
core   +1 more source

Liver Sinusoid on a Chip: Long-Term Layered Co-Culture of Primary Rat Hepatocytes and Endothelial Cells in Microfluidic Platforms

, 2015
We describe the generation of microfluidic platforms for the co-culture of primary hepatocytes and endothelial cells; these platforms mimic the architecture of a liver sinusoid. This paper describes a progressional study of creating such a liver sinusoid
Bouchard, Michael J., Cirillo, Joseph, Kang, Young Bok (Abraham), Lamontagne, Jason, Noh, Moses, Rajiv, Caroline, Sodunke, Temitope R.   +6 more
core   +1 more source

Population‐Based Molecular Surveillance of Hepatitis B Virus Genotypes in the Goto Islands, Japan: A Three Decade Study (1977–2008) of 916 Carriers

Hepatology Research, EarlyView.
ABSTRACT Aims Understanding the molecular characteristics and genotype distribution of hepatitis B virus (HBV) is essential to elucidate intra and inter community transmission routes, identify cluster cases, and assess clinical implications based on genotype‐specific virulence.
Ko Ko, Golda Akuffo Ataa, Kazumi Yamasaki, Kazuhiro Hirase, Takahiro Yasaka, Satoshi Shirahama, Tomoyuki Akita, Aya Sugiyama, Shingo Fukuma, Kazuaki Takahashi, Junko Tanaka   +10 more
wiley   +1 more source

Efficacy Analysis of TACE Combined with Lenvatinib and PD-1 Inhibitors in the Treatment of Hepatitis B Virus-Related Unresectable Hepatocellular Carcinoma

Journal of Hepatocellular Carcinoma
Jin Yu,1 Yuan Zhu,1 Shiyi Zhao,1 Xiaogang Li2 1School of Medicine, Wuhan University of Science and Technology, Wuhan, 430065, People’s Republic of China; 2Department of Biliary and Pancreatic Surgery, Xiangyang Central Hospital, Affiliated Hospital of ...
Yu J, Zhu Y, Zhao S, Li X
doaj  

Immune non‐response despite effective antiretroviral therapy in people living with HIV: A review of potential mechanisms, biomarkers and therapeutic approaches

HIV Medicine, EarlyView.
Abstract Introduction A proportion of people living with HIV (PLWH) fail to restore their CD4 count or their CD4/CD8 ratio despite effective antiretroviral therapy (ART). PLWH with immune non‐response (INR) are at a higher risk of both AIDS and non‐AIDS events. The underlying mechanisms of INR remain unclear.
Charlotte Silvestre, Antoine Gross, Alain Makinson   +2 more
wiley   +1 more source

Chloroplast and Cell Imaging at Submicron Resolution by Two-Photon Excitation [PDF]

, 2012
Novel, two-photon NIR excitation fluorescence correlation microspectroscopy tests and preliminary results were presented in this article with submicron resolution for concentrated suspensions of functional cells and chloroplast membranes.
I C. Baianu
core   +1 more source