Results 131 to 140 of about 69,966 (266)

Harnessing the Therapeutic Potential of Cell Secretomes and Extracellular Vesicles for Craniofacial Regenerative Applications

open access: yesJournal of Periodontal Research, EarlyView.
The scoping review summarizes the current preclinical and clinical evidence for the use of “cell‐free” therapies in craniofacial (periodontal, bone and soft‐tissue) regeneration. It also aims to highlight key challenges and strategies towards the clinical translation of these therapies.
Siddharth Shanbhag   +6 more
wiley   +1 more source

The Role of Viruses in the Pathogenesis of Periodontitis

open access: yesJournal of Periodontal Research, EarlyView.
This narrative review aimed to summarize current evidence on the presence and potential pathogenic role of viruses in periodontitis. Design: Narrative Review; Population: Patients with periodontitis; Exposure: Detection of viruses in oral samples (biopsies, saliva, gingival crevicular fluid, subgingival plaque, blood); Outcome: Viral prevalence, load ...
Kim Natalie Stolte   +2 more
wiley   +1 more source

Hepatitis B virus in silvery gibbons (Hylobates moloch)

open access: yes, 2004
This research investigated a number of issues regarding hepatitis B virus (HBV) in the silvery gibbon (Hylobates moloch). Due to the relatively recent discovery of the virus in nonhuman primate populations, specific knowledge of the biological behaviour ...
Payne, Karen Louise
core  

Invalid Nucleic Acid Test Results May Limit Deceased Donor Organ Utilization

open access: yesTransplant Infectious Disease, EarlyView.
Rare instances occur in which discriminatory NAT results cannot be resolved in deceased organ donor cases. When these events occur the impact on organ donation can be substantial. ABSTRACT Background Nucleic acid testing (NAT) is essential for detecting transmissible viral infections in deceased organ donors and guiding safe organ allocation.
Sara Dionne   +5 more
wiley   +1 more source

Impaired hematopoiesis affects apheresis and CAR T‐cell product composition and treatment response

open access: yesTransfusion, EarlyView.
Abstract Background Chimeric antigen receptor (CAR) T‐cell therapy has transformed the treatment of hematologic malignancies, but its success depends on obtaining sufficient CD3+ T‐cell yields during leukapheresis. This can be difficult in heavily pretreated patients, who often show leukopenia and reduced T‐cell fitness.
Hanna Kuhn   +14 more
wiley   +1 more source

Safety and tolerability of amustaline/glutathione pathogen‐reduced red blood cells in neonatal rats

open access: yesTransfusion, EarlyView.
Abstract Background Amustaline (S‐303)/glutathione (GSH) pathogen‐reduced red blood cells (PR‐RBCs) are in development for all adult and pediatric RBC transfusion indications, including neonates and infants. A neonatal rat model evaluated the safety and tolerability of PR‐RBCs during growth and maturation. Study Design and Methods Repeated transfusions
Anne North   +3 more
wiley   +1 more source

Quantification of hepatitis B virus (HBV) DNA and HBV genotyping simultaneously in plasma using real-time polymerase chain reaction

open access: yesJournal of Associated Medical Sciences, 2018
Background: in Thailand, an estimated three million people are chronically infected with hepatitis B virus (HBV), mostly with genotypes C and B. Level of HBV replication as measured by quantification of HBV DNA in blood is crucial for management of ...
Woottichai Khamduang   +5 more
doaj  

ANALYSIS OF DETECTION OF HBV-NRAg IN SERUM AND ITS CORRELATION WITH HBV DNA [PDF]

open access: yes, 2007
[目的]了解HBV携带者血清HBV-NRAg的检出情况,探讨HBV感染后HBV-NRAg与HBVM、HBVDNA载量的相关性。[方法]连续收集了从业人员的体检标本(n=4968),ELISA法检测血清HBV-NRAg和HBVM,同时以FQ-PCR检测核酸指标并辅以分区套式PCR和DNA测序作为证实检测,统计分析HBV-NRAg与HBVM、HBVDNA的相关性。[结果]HBV-NRAg的阳性率7.5%,略低于HBsAg的8.3%,略高于HBV DNA的6.8%。在HBV携带者中HBV-NRAg检测与HBV
袁权, 葛胜祥, 牛建军, 黄建炜
core  

Cord blood red cell concentrates for preterm neonate transfusion: Insights from the multicenter BORN trial

open access: yesTransfusion, EarlyView.
Abstract Background The BORN trial suggested that using cord blood‐red blood cells (CB‐RBCs) to transfuse severely preterm neonates significantly improves clinical outcomes compared to standard adult donor RBCs (A‐RBC). Study Design and Methods The study illustrates CB‐RBC concentrate production and inventory management across nine CB banks ...
Claudio Pellegrino   +38 more
wiley   +1 more source

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