Lower HBV DNA level is associated with more severe liver fibrosis in HBeAg-positive chronic hepatitis B with normal alanine transaminase. [PDF]
Background The association of hepatitis B virus (HBV) DNA levels and liver fibrosis in chronic hepatitis B (CHB) patients with immune-tolerant phase remains unclear.
Wang J +18 more
europepmc +2 more sources
HBV DNA polymerase upregulates the transcription of PD-L1 and suppresses T cell activity in hepatocellular carcinoma. [PDF]
Background In HBV-associated HCC, T cells often exhibit a state of functional exhaustion, which prevents the immune response from rejecting the tumor and allows HCC to progress.
Jia Y +6 more
europepmc +2 more sources
Real-time monitoring of serum hepatitis B virus (HBV) levels is essential for the management of patients with chronic HBV infection in clinical practice, including monitoring the resistance of anti-HBV nucleotide analog or the detection of HBV ...
Moto Watanabe +2 more
doaj +2 more sources
Comparison of HBV-DNA Levels with Biochemical and Microbiological Parameters for Chronic Hepatitis Evaluation, Bursa, Turkey [PDF]
Introduction: HBV-DNA levels are used to diagnose chronic hepatitis B (CHB) disease, determine the infection phase, decide on the treatment, and determine the disease course.
Sanem Karadag Gecgel
doaj +2 more sources
Ubiquitous expression of HBsAg from integrated HBV DNA in patients with low viral load.
BACKGROUND & AIMS Loss of serum hepatitis B surface antigen (HBsAg) is a hallmark of spontaneous and therapy induced resolution of HBV infection, since it generally reflects a profound decrease in viral replication.
Marie-Anne Meier +5 more
semanticscholar +1 more source
Liver biopsies are recommended to exclude significant liver inflammation in patients with chronic hepatitis B (CHB) with elevated HBV DNA but without other indications for antiviral treatment.
Jiacheng Liu +15 more
semanticscholar +1 more source
Signature of chronic hepatitis B virus infection in nails and hair
Background Hepatitis B virus (HBV) is detected in extrahepatic tissues of individuals with HBV infection. Whether nails and hair contain HBV has been unknown.
Haruki Komatsu +7 more
doaj +1 more source
Hepatitis B virus infection in human immunodeficiency virus infected southern African adults: occult or overt--that is the question. [PDF]
Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) share transmission routes and are endemic in sub-Saharan Africa. The objective of the present study was to use the Taormina definition of occult HBV infection, together with stringent ...
Trevor G Bell +3 more
doaj +1 more source
Impact of HCV viremia on HBV biomarkers in patients coinfected with HBV and HCV
Backgrounds: Hepatitis B virus (HBV) biomarkers reflect the status of HBV infection; however, their role in patients with chronic hepatitis B and C (HBV/HCV) coinfection remains unknown.
Chih-Wei Tseng +4 more
doaj +1 more source

