Results 51 to 60 of about 2,204,237 (310)
HBV-Integration Studies in the Clinic: Role in the Natural History of Infection
Viruses, 2021 Hepatitis B virus (HBV) infection is a major global health problem causing acute and chronic liver disease that can lead to liver cirrhosis and hepatocellular carcinoma (HCC). HBV covalently closed circular DNA (cccDNA) is essential for viral replication
Teresa Pollicino, Giuseppe Caminiti
doaj +1 more source
Expression in Escherichia coli of a cloned DNA sequence encoding the pre-S2 region of hepatitis B virus [PDF]
, 1985 A DNA sequence encoding the entire pre-S2 region (amino acids 120-174; serotype ayw) of human hepatitis B virus envelope protein has been inserted into the lacZ gene of the plasmid pSKS105 yielding a recombinant, pWS3.
Acs, George +7 more
core +1 more source
The cyclophilin inhibitor CRV431 inhibits liver HBV DNA and HBsAg in transgenic mice
PLoS ONE, 2019 Hepatitis B virus (HBV) infection is a major health burden worldwide with 240 million chronically infected individuals. Nucleos(t)ide analogs and interferons are the current standards of care due to their suppression of HBV replication, but the ...
P. Gallay +6 more
semanticscholar +1 more source
HBV‐DNA levels predict overall mortality in HIV/HBV coinfected individuals
Journal of Medical Virology, 2015 The coinfection of Hepatitis B virus (HBV) and human immunodeficiency virus (HIV) has been associated with increased death rates. However, the relevant research has mostly relied on serologic HBV testing [HBV surface antigen (HBsAg)]. The aim of this work was to explore the relationship of HBV viraemia with overall mortality among HIV/HBV coinfected ...
Nikolopoulos, Georgios K. +7 more
openaire +4 more sources
Detection of HBV Covalently Closed Circular DNA [PDF]
Viruses, 2017 Chronic hepatitis B virus (HBV) infection affects approximately 240 million people worldwide and remains a serious public health concern because its complete cure is impossible with current treatments. Covalently closed circular DNA (cccDNA) in the nucleus of infected cells cannot be eliminated by present therapeutics and may result in persistence and ...
Xiaoling Li +3 more
openaire +3 more sources
The Role Placental TLR-7 Expression with Cord Blood HBV DNA and Placental HBV DNA
Indonesian Journal of Obstetrics and Gynecology, 2022 Abstract Objective: To determine the role of TLR-7 expression on intrauterine vertical transmission in pregnancy through identification of serum hepatitis B markers in both maternal and umbilical cord blood. Methods: Analysis of TLR expression was performed on 38 paraffin block samples of placental tissue acquired from mothers with HBV using TLR ...
Naeny Fajriah +5 more
openaire +3 more sources
Kaohsiung Journal of Medical Sciences, 2015 This study was to elucidate longitudinally quantitative changes of hepatitis B virus (HBV) surface antigen (HBsAg) and HBV DNA in elder HBsAg carriers in a community.
Yuan-Hung Kuo +6 more
doaj +1 more source
Virology Journal, 2021 Background Hepatitis B virus (HBV) serum markers during typical acute self-limited infection are usually depicted as a composite of traditional HBV markers.
Mary C. Kuhns +4 more
doaj +1 more source
Core promoter: A critical region where the hepatitis B virus makes decisions [PDF]
, 2014 The core promoter (CP) of the viral genome plays an important role for hepatitis B virus (HBV) replication as it directs initiation of transcription for the synthesis of both the precore and pregenomic (pg) RNAs.
Quarleri, Jorge Fabian
core +1 more source
The prevalence of occult hepatitis B virus (hbv) infection in a large multi-ethnic haemodialysis cohort. [PDF]
, 2015 Haemodialysis patients are at increased risk of exposure to blood borne viruses. To reduce transmission in the UK, all haemodialysis patients are regularly screened, and if susceptible to Hepatitis B virus (HBV) infection ...
Cross, J +6 more
core +1 more source