HER2/neu Testing In 432 Consecutive Breast Cancer Cases using FISH and IHC - A Comparative Study [PDF]
Introduction: The development of trastuzumab, a HER-2/ neu targeted monoclonal antibody resulted in significant improvements in clinical response and survival in HER-2/neu gene amplified group of patients.
Venkataswamy Eswarachary +7 more
doaj +1 more source
hCG, Hyperglycosylated hCG, Pituitary hCG, Cancer hCG and Fetal hCG
Human chorionic gonadotropin (hCG) is a one-of-a-kind biochemical. The amino acid sequence of the α- and s-subunits codes for six semi-independent molecules, binding two separate receptors, the lutropin (LH)/hCG hormone and the transforming growth factor-s (TGFs) autocrine receptor. The six semi-independent molecules each vary by carbohydrate structure,
openaire +1 more source
Mass Mimicking Autoimmune Pancreatitis—A Report of Two Cases and Review of Literature
Autoimmune pancreatitis (AIP) consists of two clinically histologically distinct forms (type I and II) of chronic pancreatitis that are histologically different. These forms of AIP classically respond to oral steroids.
Diva S. Shah +5 more
doaj +1 more source
Extented ionized gas emission and kinematics of the compact group galaxies in HCG 16: Signatures of mergers [PDF]
We report on kinematic observations of Ha emission line from four late-type galaxies of Hickson Compact Group 16 (H16a,b,c and d) obtained with a scanning Fabry-Perot interferometer and samplings of 16 km/s and 1".
Amram P. +15 more
core +2 more sources
Concerted action of human chorionic gonadotropin and norepinephrine on intracellular-free calcium in human granulosa-lutein cells [PDF]
Luteal cells are known to possess receptors for LH/hCG and receptors of the beta-adrenergic type. Interactions of specific agonists with either receptor lead to the activation of adenylate cyclase and subsequently to an increase of cAMP.
Föhr, K. J. +5 more
core +1 more source
Deep Optical Observations of Compact Groups of Galaxies [PDF]
Compact groups of galaxies appear to be extremely dense, making them likely sites of intense galaxy interaction, while their small populations make them relatively simple to analyze.
Bregman, Joel N. +2 more
core +2 more sources
Globular Cluster Population of Hickson Compact Group 22a and 90c
We present the first measurement of the globular cluster populations of galaxies in Hickson compact groups, in order to investigate the effect of these high density environments on the formation and evolution of globular cluster systems. Based on V and R
Barnes J. +9 more
core +2 more sources
Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism [PDF]
Cancer cells must satisfy the metabolic demands of rapid cell growth within a continually changing microenvironment. We demonstrated that the dynamic posttranslational modification of proteins by O-linked β-N-acetylglucosamine (O-GlcNAcylation) is a key ...
Clark, Peter M. +8 more
core +2 more sources
Immunoreactive human chorionic gonadotropin and its free ß-subunit in serum and ascites of patients with malignant tumors [PDF]
Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ...
Gerbes, Alexander L. +4 more
core
TMC4 localizes to multiple taste cell types in the mouse taste papillae
Transmembrane channel‐like 4 (TMC4), a voltage‐dependent chloride channel, plays a critical role in amiloride‐insensitive salty taste transduction. TMC4 is broadly expressed in all mature taste cell types, suggesting a possible involvement of multiple cell types in this pathway.
Momo Murata +6 more
wiley +1 more source

