HER2/neu Testing In 432 Consecutive Breast Cancer Cases using FISH and IHC - A Comparative Study [PDF]
Introduction: The development of trastuzumab, a HER-2/ neu targeted monoclonal antibody resulted in significant improvements in clinical response and survival in HER-2/neu gene amplified group of patients.
Venkataswamy Eswarachary +7 more
doaj +1 more source
Two formation channels of UCDs in Hickson Compact Groups [PDF]
The formation of ultra-compact dwarf galaxies (UCDs) is believed to be interaction driven, and UCDs are abundant in the cores of galaxy clusters, environments that mark the end-point of galaxy evolution.
Anders +87 more
core +1 more source
hCG, Hyperglycosylated hCG, Pituitary hCG, Cancer hCG and Fetal hCG
Human chorionic gonadotropin (hCG) is a one-of-a-kind biochemical. The amino acid sequence of the α- and s-subunits codes for six semi-independent molecules, binding two separate receptors, the lutropin (LH)/hCG hormone and the transforming growth factor-s (TGFs) autocrine receptor. The six semi-independent molecules each vary by carbohydrate structure,
openaire +1 more source
Mass Mimicking Autoimmune Pancreatitis—A Report of Two Cases and Review of Literature
Autoimmune pancreatitis (AIP) consists of two clinically histologically distinct forms (type I and II) of chronic pancreatitis that are histologically different. These forms of AIP classically respond to oral steroids.
Diva S. Shah +5 more
doaj +1 more source
Kinematics of galaxies in Compact Groups. Studying the B-band Tully-Fisher relation [PDF]
We obtained new Fabry-Perot data cubes and derived velocity fields, monochromatic and velocity dispersion maps for 28 galaxies in the Hickson compact groups 37, 40, 47, 49, 54, 56, 68, 79 and 93.
Amram +50 more
core +1 more source
Androgen-responsive non-coding small RNAs extend the potential of HCG stimulation to act as a bioassay of androgen sufficiency [PDF]
Background: It is unclear whether a short-term change in circulating androgens is associated with changes in the transcriptome of the peripheral blood mononuclear cells (PBMC).
Ahmed, S.F. +7 more
core +1 more source
Globular Cluster Population of Hickson Compact Group 22a and 90c
We present the first measurement of the globular cluster populations of galaxies in Hickson compact groups, in order to investigate the effect of these high density environments on the formation and evolution of globular cluster systems. Based on V and R
Barnes J. +9 more
core +2 more sources
Background: Eribulin mesylate is a non-taxane microtubule inhibitor which can be used after anthracycline and taxane treatment in patients with metastatic breast cancer (MBC).
BJ Srinivasa +11 more
doaj +1 more source
Immunoreactive human chorionic gonadotropin and its free ß-subunit in serum and ascites of patients with malignant tumors [PDF]
Human chorionic gonadotropin (hCG) is a clinically relevant marker of trophoblastic and nontrophoblastic malignancies. In the present studies, in addition to determining serum hCG, we investigated the presence and properties of hCG immunoreactivity in ...
Gerbes, Alexander L. +4 more
core
Phosphofructokinase 1 Glycosylation Regulates Cell Growth and Metabolism [PDF]
Cancer cells must satisfy the metabolic demands of rapid cell growth within a continually changing microenvironment. We demonstrated that the dynamic posttranslational modification of proteins by O-linked β-N-acetylglucosamine (O-GlcNAcylation) is a key ...
Clark, Peter M. +8 more
core +2 more sources

