Results 41 to 50 of about 63,442 (308)

Labelless impedance immunosensor based on polypyrrole-pyrolecarboxylic acid copolymer for hCG detection [PDF]

, 2011
In this work, a sensitive label-free impedimetric hCG-immunosensor was constructed by using a commercial screen-printing carbon ink electrode (namely Disposable Electrochemical Printed chip) as the basis.
Takamura, Yuzuru, Yoshiaki Ukita, Ukita, Yoshiaki, Truong, Lien T.N., Lien T.N. Truong, Chikae, Miyuki, Yuzuru Takamura, Miyuki Chikae   +7 more
core   +1 more source

Fosl2 Regulates FSH‐Dependent Follicle Maturation Through Feedback Amplification of FSH/FSHR Signaling

Advanced Science, EarlyView.
This study identifies a FOSL2‐driven positive feedback loop that amplifies FSH/FSHR signaling. During FSH‐dependent follicle maturation, FSH induces Fosl2 expression via the cAMP‐PKA‐CREB cascade. FOSL2 in turn binds the promoters of Fshr and estrogen‐biosynthesis genes to enhance their transcription, thereby increasing Fshr mRNA level and amplifying ...
Hongru Shi, Chaoli Chen, Zaohong Ran, Jianning Liao, Zian Wu, Xiaodong Wang, Yongheng Zhao, Wenkai Ke, Bowen Tan, Yun Liu, Youqiang Su, Wei Ren, Xiang Li, Changjiu He   +13 more
wiley   +1 more source

Investigation of factors influencing the immunogenicity of hCG as a potential cancer vaccine [PDF]

, 2018
Human chorionic gonadotrophin (hCG) and its β‐subunit (hCGβ) are tumour autocrine growth factors whose presence in the serum of cancer patients has been linked to poorer prognosis.
Justesen, J., N Chikadze, Roitt, I.M., F A Hills, Martensen, P., J Makinde, Lund, T., J D McBride, J Justesen, Kvirkvelia, N., P J Delves, T Lund, I M Roitt, P M Martensen, N Kvirkvelia, Chikadze, N., N Porakishvili, Delves, P.J., Porakishvili, N.   +18 more
core   +1 more source

Natural Resistance to Ovarian Hyperstimulation Syndrome in Estrildid Finches Reveals Macrophage GPR183 as a Potential Therapeutic Target

Advanced Science, EarlyView.
Ovarian macrophage depletion reverses OHSS resistance in estrildid finches and exacerbates OHSS symptoms in rats. Activating macrophage GPR183 alleviates OHSS by reducing pro‐inflammatory factors, increasing immunomodulatory molecules, remodeling CD44/SDC4‐mediated communication, and restoring immune homeostasis.
Xiaofei Yan, Yongjie Huang, Jiabao Yang, Su Ma, Songsong Liu, Xuan Huang, Juergen Brosius, Huaping Zheng, Bing Yao, Li Chen, Shanshan Lai, Cheng Deng   +11 more
wiley   +1 more source

A Rare Case of Amelanotic Mucosal Malignant Melanoma of the Penis: First of Its Kind Case Report from India

Libyan International Medical University Journal
Amelanotic mucosal malignant melanoma of the penis is extremely rare. To our knowledge, this is the first case from India. In the present case report, we have discussed the diagnostic challenges, treatment, and prognosis related with this rare condition.
Soundarya Varadarajan, Vikas Jain, Raj Nagarkar, Sucheta Gandhe, Yasam Venkata Ramesh   +4 more
doaj   +1 more source

hCG concentration from individual samples of EP-hCG and LP-hCG.

, 2020
hCG concentration from individual samples of EP-hCG and LP-hCG.
Shabnam Bobdiwala (8436768), Maria Panico (245670), Stuart M. Haslam (208187), Anne Dell (79797), Linda Ibeto (8436765), Gary Clark (8436777), Mark R. Johnson (117795), Maya Al-Memar (8436771), Aristotelis Antonopoulos (1856338), Paola Grassi (191372), Julian Norman Taylor (8436774), Tom Bourne (175288), Michael Seckl (7055864), Poh-Choo Pang (5663056), Mark Davis (144230), Paul Davis (5775), Paula Almeida (5449031), Richard Harvey (619603)   +17 more
core   +1 more source

Placental Site Trophoblastic Tumor Acquires Immune Functions by Incorporating Host Maternal Genes

Advanced Science, EarlyView.
PSTT cells, through cell fusion with B cells, incorporate abundant non‐inherited maternal genes that are detectable by DNIMA. These hybrid cells acquire immunotherapy‐resistant genetic changes and increase the expression of B cell‐derived immune‐related molecules such as Ig, HLA, LILRB, SIGLEC10, and so on, creating an immunotolerant environment around
Kyosuke Kagami, Masanori Ono, Yasunari Mizumoto, Tatsuhito Kanda, Takashi Iizuka, Takiko Daikoku, Shin‐ichi Horike, Akira Hattori, Akihito Horie, Sachiko Minamiguchi, Tomoko Fujiwara, Kazuyoshi Hosomichi, Atsushi Tajima, Hirokazu Usui, Kaoru Abiko, Hiroshi Fujiwara   +15 more
wiley   +1 more source

A case report of high-grade astroblastoma in a young adult

CNS Oncology, 2019
Astroblastoma is an uncommon neuroepithelial primary tumor of the brain which is of uncertain origin. We present a case of high-grade astroblastoma in an 18-year-old female with a severe headache, loss of appetite, vomiting and generalized weakness.
Sagar Bhalerao, Rajnish Nagarkar, Aditya Adhav   +2 more
doaj   +1 more source

Evaluation of Maternal Serum PAPP-A and hCG Levels at 10-14 Weeks of Gestation in Hyperemesis Gravidarum

, 2020
Aim:The aim of this study is to determine the relationship between hyperemesis gravidarum and maternal serum pregnancy-associated plasma protein A (PAPP-A) and human chorionic gonadotropin (hCG) levels.
Anıl Turhan Çakır, Ahmet Birtan Boran
core   +1 more source

NAD+ Metabolism Licenses Zygotic Genome Activation via PARP7‐Mediated ADP‐Ribosylation of UHRF1 in Mouse Early Embryos

Advanced Science, EarlyView.
This study uncovers a metabolic‐epigenetic axis licensing zygotic genome activation (ZGA) in mouse embryos. A developmental decline in NAD+ levels activates PARP7, which mono‐ADP‐ribosylates and stabilizes UHRF1. This modification promotes the establishment of permissive histone acetylation marks, thereby facilitating timely ZGA.
Guangyi Cao, Ziqi Zhang, Anqi Chen, Yanbo Liu, Yuling Lin, Lina Yu, Ruixin Shi, Aolei Guo, Yan Mao, Ganggui Lou, Chaojun Li, Luhong Wen, Guijun Yan, Haixiang Sun   +13 more
wiley   +1 more source