Results 1 to 10 of about 8,837 (206)

Regulation of human chorionic gonadotropin beta subunit expression in ovarian cancer [PDF]

BMC Cancer, 2019
Purpose Expression of human chorionic gonadotropin beta subunit by cancers is extensively documented, yet regulation of the multiple genes that can code for this protein is poorly understood.
Aleksandra Śliwa, Marta Kubiczak, Anna Szczerba, Grzegorz Walkowiak, Ewa Nowak-Markwitz, Beata Burczyńska, Stephen Butler, Ray Iles, Piotr Białas, Anna Jankowska   +9 more
doaj   +3 more sources

Reduction of human chorionic gonadotropin beta subunit expression by modified U1 snRNA caused apoptosis in cervical cancer cells [PDF]

Molecular Cancer, 2008
Background Secretion of human chorionic gonadotropin, especially its beta subunit by malignant trophoblastic tumors and varieties of tumors of different origin is now well documented; however the role of hCG in tumorogenesis is still unknown.
Jarmolowski Artur, Szczerba Anna, Burczynska Beata, Andrusiewicz Miroslaw, Gunderson Samuel I, Jankowska Anna, Nowak-Markwitz Ewa, Warchol Jerzy B   +7 more
doaj   +5 more sources

CGB and GNRH1 expression analysis as a method of tumor cells metastatic spread detection in patients with gynecological malignances [PDF]

Journal of Translational Medicine, 2011
Background Metastasis is a common feature of many advanced stage cancers and metastatic spread is thought to be responsible for cancer progression. Most cancer cells are localized in the primary tumor and only a small population of circulating tumor ...
Gąsiorowska Emilia, Nowak-Markwitz Ewa, Warchoł Wojciech, Wołuń-Cholewa Maria, Szczerba Anna, Andrusiewicz Mirosław, Adamska Krystyna, Jankowska Anna   +7 more
doaj   +3 more sources

Mola hidatiforme e doença trofoblástica gestacional Hydatidiform mole and gestational trophoblastic disease [PDF]

Revista Brasileira de Ginecologia e Obstetrícia, 2009
A mola hidatiforme é uma complicação relativamente infrequente da gravidez, mas com potencial para evolução para formas que necessitam de tratamento sistêmico e podem ser ameaçadoras da vida.
Jurandyr Moreira de Andrade
doaj   +4 more sources

The Association and diagnostic value between Maternal Serum Placental Markers and Placenta Previa [PDF]

European Journal of Obstetrics & Gynecology and Reproductive Biology: X
Objective: This study aims to evaluate the correlation and diagnostic value of maternal serum placental markers: pregnancy-associated plasma protein-A (PAPP-A), free beta human chorionic gonadotropin (free β-hCG), and alpha fetoprotein (AFP) in relation ...
Panpan Ma, Tingting Hu, Yiming Chen
doaj   +2 more sources

Predictive value of the maternal alpha-fetoprotein variant, L2, during the first trimester of pregnancy screening for fetal trisomy 21, trisomy 18, and neural tube defects [PDF]

BMC Pregnancy and Childbirth
Background To assess the predictive usefulness of maternal serum alpha fetoprotein variant L2 (AFP-L2) for fetal trisomy 21, trisomy 18, and neural tube abnormalities (NTDs) in early pregnancy screening.
Yiming Chen, Wenwen Ning, Caihe Wen, Linyuan Gu, Xuelian Chu   +4 more
doaj   +2 more sources

Protocol for a prospective observational cohort study to assess clinical applications of expanded noninvasive prenatal testing (NIPT) in pregnancies with placental dysfunction. [PDF]

PLoS ONE
IntroductionExpanded non-invasive prenatal testing (NIPT) utilizing cell-free DNA (cfDNA) in maternal blood enables the detection of common trisomies as well as rare autosomal trisomies and large deletions and duplications within the genome of the ...
Ana Villalba, M Ángeles Sánchez-Durán, Carmen Orellana, Mercedes Sobreviela, María M Gil, Rosa María Lobo, Irene Gómez-Manjón, Cristina Cea, Laia Pedrola Vidal, Sebastian Menao, Raquel Martin-Alonso, Gonzalo E Quesada, Eva Albuixech, Mónica Roselló Piera, Eva Valle, Eduardo Tizzano, Alberto Galindo, Manel Mendoza, Beatriz Marcos, José Vicente Cervera, Belén Santacruz, Daniela Piazzolla, Lieve Page-Christiaens, Diego Lerma, Ramiro Quiroga, Francisco Javier Fernández, Ignacio Herraiz   +26 more
doaj   +2 more sources

Biochemical and ultrasonographic markers in fetal surveillance [PDF]

Srpski Arhiv za Celokupno Lekarstvo, 2023
Introduction/Objective. Fetal growth restriction (FGR) is associated with increased fetal and neonatal mortality and morbidity. The study objective was to investigate the correlation of maternal blood biochemical markers routinely determined in the first
Kocijančić-Belović Dušica, Dotlić Jelena, Akšam Slavica   +2 more
doaj   +1 more source

Testicular germ cell tumors type 2 have high RNA expression of LDHB, the gene for lactate dehydrogenase subunit B

Asian Journal of Andrology, 2021
This study analyzed RNA expression of genes for three serum tumor markers, alpha fetoprotein (AFP), human chorionic gonadotropin (hCG), and lactate dehydrogenase (LDH), in patients with testicular germ cell tumors (TGCT) type 2. The gene AFP encodes AFP,
Finn Edler von Eyben, Jorge Parraga-Alava, Shi-Ming Tu   +2 more
doaj   +1 more source

Ectopic Production of the Isolated Beta Subunit of Human Chorionic Gonadotropin [PDF]

Journal of Clinical Investigation, 1973
A material similar to the beta subunit of human chorionic gonadotropin (hCG-beta) was detected in serum (300 ng/ml) and tumor extract from a 75-yr-old man with pancreatic adenosquamous carcinoma. This material was indistinguishable from hCG-beta in three different types of radioimmunoassay that displayed widely varying reactions with glycoprotein ...
B D, Weintraub, S W, Rosen
openaire   +2 more sources