The crystal structure of the β subunit of luteinizing hormone and a model for the intact hormone
The β subunit of bovine luteinizing hormone (LH) was crystallized and its structure solved to 3.15 Å resolution by molecular replacement using human chorionic gonadotropin (hCG) β subunit as search model. The asymmetric unit contains two copies of the β
Steven B. Larson, Alexander McPherson
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Postmenopausal pregnancy: A case report
Abnormal vaginal bleeding is one of the complaints of women during menopause. Various diseases such as endometrial atrophy, polyps, and endometrial cancers may lead to postmenopausal vaginal bleeding.
Rafat Mirsafi, Mahtab Attarha
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Various carboxyl-terminal peptides of hCG-β were prepared from the corresponding blocked peptides by TFA treatment followed by hydrogenation. The prepared peptides were tested for inhibitory action on the binding between 125I-hCG and the antiserum against the carboxyl-terminal portion of hCG-β.
KAWASAKI, KOICHI +8 more
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Pulmonary Metastatic Choriocarcinoma in a Patient with Ectopic Pregnancy [PDF]
Gestational trophoblastic tumor (GTT) most commonly follows a molar pregnancy. In fact, it can occur following gestational events such as induced or spontaneous abortion, ectopic pregnancy, and term pregnancy.
Fahimeh Nokhostin +2 more
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Beta-HCG secretion by a pulmonary pleomorphic carcinoma: A case report
Ectopic secretion of beta-subunit of human chorionic gonadotropin (β-HCG) in pulmonary pleomorphic carcinoma is remarkably rare. Such unusual ectopic hormone production by lung cancer may be initially misinterpreted as extragonadal choriocarcinoma or ...
Magno Dinis de Sousa +6 more
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Diagnostic validity of a marker model of first trimester in pregnancy in prediction of birth weight [PDF]
Background/Aim. Nowadays, low birth weight is considered to be one of the main causes of cardiovascular diseases or metabolic syndrome occurring later in life.
Vujović Slavica +3 more
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Stimulation of hCG protein and mRNA in first trimester villous cytotrophoblast cells in vitro by glycodelin A [PDF]
Aim: Human chorionic gonadotropin (hCG) is produced by fetal trophoblast cells and secreted into maternal circulation mainly in the first trimester of pregnancy.
Richter, Dagmar-Ulrike +15 more
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A case of gynecomastia from a βhCG secreting bladder tumour
Background: Beta human chorionic gonadotropin (βhCG) is a glycoprotein secreted by trophoblastic cells during gestation. Various solid epithelial cancers can raise levels of βhCG and can cause gynecomastia. There are a few case reports that show elevated
Kathrine Lee-A-Ping, Jimmy Li Voon Chong
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Assignment of disulfide bonds in the beta subunit of human chorionic gonadotropin.
The assignment of five disulfide bonds in the alpha subunit of human chorionic gonadotropin (hCG) using partial reduction and S-[14C]carboxymethylation has been reported earlier (Mise, T., and Bahl, O. P. (1980) J. Biol. Chem. 255, 8516-8522). Employing a similar approach, we have determined the locations of six disulfide bonds in hCG-beta.
T, Mise, O P, Bahl
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Predictive value of extreme low PAPP-A, free βhCG and extreme high mean uterine artery pulsatility index in the first trimester for fetal growth restriction [PDF]
Background/Aim. Adverse pregnancy outcomes such as preeclampsia (PE), placental abruption (PA), fetal intrauterine growth restriction (IUGR) and stillbirth could be recognized by prenatal screening.
Lukić Relja +4 more
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