Results 41 to 50 of about 105,771 (267)

Cytoplasmic p21 promotes stemness of colon cancer cells via activation of the NFκB pathway

Molecular Oncology, EarlyView.
Cytoplasmic p21 promotes colorectal cancer stem cell (CSC) features by destabilizing the NFκB–IκB complex, activating NFκB signaling, and upregulating BCL‐xL and COX2. In contrast to nuclear p21, cytoplasmic p21 enhances spheroid formation and stemness transcription factor CD133.
Arnatchai Maiuthed, Kerstin Huebner, Katharina Erlenbach‐Wuensch, Chuanpit Hampel, Daniela Thalheim, Adriana Vial‐Roehe, Bodee Nutho, Susanne Merkel, Arndt Hartmann, Pithi Chanvorachote, Regine Schneider‐Stock   +10 more
wiley   +1 more source

Association between tumour stroma ratio and other histopathological markers and lymph node metastasis in patients with oral cavity cancer

The Egyptian Journal of Otolaryngology
Background Tumour stroma ratio (TSR) has recently been introduced as a promising prognostic parameter in oral cavity cancers. However, the correlation between TSR and histopathological markers in oral cavity squamous cell carcinoma (OCSCC) patients was ...
Prakash Pandit, Vijay Palwe, Sai Krishna U., Sucheta Gandhe, Yogesh Pawar, Yasam Venkata Ramesh, Raj Nagarkar   +6 more
doaj   +1 more source

Dihydroorotate dehydrogenase (DHODH) regulates trophoblast syncytialization through organelle stress–induced cellular senescence

FEBS Open Bio, EarlyView.
The inhibition of mitochondrial dihydroorotate dehydrogenase (DHODH) impairs syncytialization and induces cellular senescence via mitochondrial and endoplasmic reticulum stress in human trophoblast stem cells, elevating sFlt1/PlGF levels, a hallmark of placental dysfunction in hypertensive disorders of pregnancy.
Kanoko Yoshida, Kazuya Kusama, Ayaka Horiuchi, Yu Kawaguchi, Atsuya Tsuru, Mikihiro Yoshie, Kazuhiro Tamura   +6 more
wiley   +1 more source

The 10–23 DNAzyme in Biosensing and Diagnostics: Applications, Challenges, and Future Directions

Angewandte Chemie, EarlyView.
This review focuses on the 10–23 DNAzyme in diagnostics, spanning unregulated and regulated target‐recognition modes, and their functionalization across colorimetric, fluorescent, electrochemical, electrochemiluminescent, and intracellular biosensing strategies.
Connor Nurmi, Jake Brill, Sanne Roumans, Amal Mathai, John D. Brennan, Yingfu Li   +5 more
wiley   +2 more sources

Intra-group Light in Hickson Compact Groups

, 2005
We have analyzed the intra-group light component of 3 Hickson Compact Groups (HCG 79, HCG 88 and HCG 95) with detections in two of them: HCG 79, with $46\pm11%$ of the total $B$ band luminosity and HCG 95 with $11\pm26%$. HCG 88 had no component detected.
Da Rocha, Cristiano, de Oliveira, Claudia Mendes, Ziegler, Bodo L.   +2 more
core   +1 more source

The HI Content of Compact Groups of Galaxies [PDF]

, 2004
The HI content of Hickson Compact Groups in the southern hemisphere is measured using data from the HI Parkes All Sky Survey (HIPASS), and dedicated observations using the narrowband filter on the Multibeam instrument on the Parkes telescope.
Barnes, Braun, Chamaraux, Chamaraux, D. G. Barnes, D. J. Pisano, de Vaucouleurs, Hickson, Huchtmeier, Huchtmeier, J. B. Stevens, Karachentseva, Leon, M. J. Drinkwater, Nilson, R. L. Webster, Sandage, Verdes-Montenegro   +17 more
core   +2 more sources

Unraveling the Molecular Mechanisms of Glioma Recurrence: A Study Integrating Single‐Cell and Spatial Transcriptomics

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Glioma recurrence severely impacts patient prognosis, with current treatments showing limited efficacy. Traditional methods struggle to analyze recurrence mechanisms due to challenges in assessing tumor heterogeneity, spatial dynamics, and gene networks.
Lei Qiu, Yinjiao Fei, Jiaxuan Ding, Kexin Shi, Jinyan Luo, Yuchen Zhu, Xingjian Sun, Gefei Jiang, Yuandong Cao, Weilin Xu, Shu Zhou   +10 more
wiley   +1 more source

THE EFFECT OF HCG, 17 Β-ESTRADIOL AND HYDROCORTISONE ON BLOOD CHOLESTEROL, [PDF]

Basrah Journal of Veterinary Research, 2009
The aim of this study is to investigate the effect of human chorionic gonadotophic (HCG), 17β-estradiol and hydrocortisone on some blood parameters and body weight in female rabbits.
Wasfi Dhahir Abd Ali Al -Mahmod
doaj   +1 more source

Comparison of the effect of trigger of ovulation with HCG and HCG plus oxytocin on the biochemical pregnancy [PDF]

Majallah-i Zanān, Māmā̓ī va Nāzā̓ī-i Īrān, 2020
Introduction: Infertility is defined as not getting pregnant after 1 year of unprotected intercourse. Given the large area and high population of Sistan & Baluchestan province and many patients referring to the infertility center of Ali-ibn-e Abitaleb ...
Shahnaz Nezamdoust, Farahnaz Farzaneh
doaj   +1 more source

Multimodal Mechanical Testing of Additively Manufactured Ti6Al4V Lattice Structures: Compression, Bending, and Fatigue

Advanced Engineering Materials, EarlyView.
In this experimental study, the mechanical properties of additively manufactured Ti‐6Al‐4V lattice structures of different geometries are characterized using compression, four point bending and fatigue testing. While TPMS designs show superior fatigue resistance, SplitP and Honeycomb lattice structures combine high stiffness and strength. The resulting
Klaus Burkart, Jonas Schmidt, Anastasiya Toenjes, Johanna Eisenträger   +3 more
wiley   +1 more source