Results 161 to 170 of about 46,134 (291)

Glucocorticosteroids trigger reactivation of human cytomegalovirus from latently infected myeloid cells and increase the risk for HCMV infection in D+R+ liver transplant patients

Journal of General Virology, 2015
Graft rejection in transplant patients is managed clinically by suppressing T-cell function with immunosuppressive drugs such as prednisolone and methylprednisolone.
Ellen Van Damme, Sarah Sauviller, B. Lau, B. Kesteleyn, P. Griffiths, A. Burroughs, V. Emery, J. Sinclair, M. Van Loock   +8 more
semanticscholar   +1 more source

The HCMV Assembly Compartment Is a Dynamic Golgi-Derived MTOC that Controls Nuclear Rotation and Virus Spread [PDF]

, 2018
Dean J. Procter, Avik Banerjee, Masatoshi Nukui, Kevin Kruse, Vadim Gaponenko, Eain A. Murphy, Yulia Komarova, Derek Walsh   +7 more
openalex   +1 more source

Retinal pericytes and cytomegalovirus infectivity: implications for HCMV-induced retinopathy and congenital ocular disease

Journal of Neuroinflammation, 2015
BackgroundHuman cytomegalovirus (HCMV) is the leading infectious cause of vision loss among congenitally infected children. Retinal pericytes play an essential role in maintaining retinal vascular and endothelial cell proliferation.
Irene Wilkerson, Joshua Laban, Johnathan M Mitchell, N. Sheibani, D. Alcendor   +4 more
semanticscholar   +1 more source

Signatures of T and B Cell Development, Functional Responses and PD-1 Upregulation After HCMV Latent Infections and Reactivations in Nod.Rag.Gamma Mice Humanized With Cord Blood CD34+ Cells [PDF]

, 2018
Sebastian J. Theobald, Sahamoddin Khailaie, Michael Meyer‐Hermann, Valery Volk, Henning Olbrich, Simon Danisch, Laura Gerasch, Andreas Schneider, Christian Sinzger, Dirk Schaudien, Stefan Lienenklaus, Peggy Riese, Carlos A. Guzmán, Constança Figueiredo, Constantin von Kaisenberg, Loukia M. Spineli, Stephanie Glaesener, Almut Meyer‐Bahlburg, Arnold Ganser, Michael Schmitt, Michael Mach, Martin Messerle, Renata Stripecke   +22 more
openalex   +1 more source

Viral hijacking of cellular metabolism. [PDF]

, 2019
This review discusses the current state of the viral metabolism field and gaps in knowledge that will be important for future studies to investigate.
Ch'ng, James, Christofk, Heather R, Thaker, Shivani K   +2 more
core  

Effect of host telomerase inhibition on human cytomegalovirus

Journal of Virology
Treatment options remain limited for human cytomegalovirus (HCMV). Host telomerase has been implicated in the pathogenesis and oncogenesis of multiple herpesviruses, most recently including HCMV.
Chloe M. Cavanaugh, Cora N. Betsinger, Nicole Katchur, Sherry Zhang, Karen Yang, Maciej Nogalski, Ileana M. Cristea, Daniel Notterman   +7 more
doaj   +1 more source

Natural killer cells as an initial defense against pathogens. [PDF]

, 2006
Natural killer (NK) cells serve as a crucial first line of defense against tumors and a diverse range of pathogens. Recognition of infection by NK cells is accomplished by the activation of receptors on the NK cell surface, which initiate NK cell ...
Lanier, Lewis L, Lodoen, Melissa B
core  

Analysis of G-quadruplexes upstream of herpesvirus miRNAs: evidence of G-quadruplex mediated regulation of KSHV miR-K12–1-9,11 cluster and HCMV miR-US33 [PDF]

, 2020
Shivani Kumar, Divya Choudhary, Anupam Patra, Néel Sarovar Bhavesh, Perumal Vivekanandan   +4 more
openalex   +1 more source

尸体肾移植术后活动性 HCMV 感染的预防性治疗

Zhongshan Daxue xuebao. Yixue kexue ban, 1999
目的: 探讨尸体肾移植术后人巨细胞病毒(HCMV)病的防治。方法: 应用 HCMV-Ag 试验诊断 HCMV 感染。对本 院实施的 1 150例尸体肾移植分两组进行回顾性分析。结果: 治疗组: 1989年 9 月～ 1997年 4 月共 1 050 例,HCMV 病 45 例,治 愈 30例, 死亡 15例; 预防组: 1997 年 5 月～ 1998 年 5 月,共 100 例,HCMV 感染 42例, 由于进行了预防性治疗,无 1例 HCMV 病 发生和因 HCMV 感染而死亡。结论: HCMV ...
郑克立　吴培根　朱兰英　洪良庆　刘　东
doaj  

Host immune response to cytomegalovirus [PDF]

, 1987
To confirm that immediate-early (IE) genes of murine cytomegalovirus (MCMV) give rise to antigens recognized by specific cytolytic T lymphocytes (CTL), a 10.8-kilobase fragment of MCMV DNA which is abundantly transcribed at IE times was transfected into ...
Keil, Günther M., Koszinowski, Ulrich H., Reddehase, Matthias J., Schickedanz, Jörg   +3 more
core