Results 91 to 100 of about 210,178 (301)

Human monoclonal antibodies to a novel cluster of conformational epitopes on HCV E2 with resistance to neutralization escape in a genotype 2a isolate [PDF]

, 2012
The majority of broadly neutralizing antibodies to hepatitis C virus (HCV) are against conformational epitopes on the E2 glycoprotein. Many of them recognize overlapping epitopes in a cluster, designated as antigenic domain B, that contains residues G530
Wenyan Wang (171659), Bukh, J., Felix A Rey, Yong Wang (12837), Wang, Yong, Zhen-yong Keck (171653), Jannick Prentoe (162323), Lemon, S.M., Jannick Prentoe, Jens Bukh (162343), Steven K. H. Foung (171667), Lemon, Stanley M., Prentoe Jannick, Foung Steven K. H., Thomas Carlsen (171662), Carlsen, Thomas, Rey, F.A., Patel, Arvind H., Li, A.Y., Patel, A.H., Steven K H Foung, Carlsen Thomas, Bukh, Jens, Xia, J., Zhen-yong Keck, Li, Angela Ying-Jian, Wenyan Wang, Keck, Zhen-yong, Thomas Krey, Wang, Y., Rey Felix A., Yong Wang, Foung, S.K.H., Arvind H. Patel (33806), Patel, Arvind H, Lemon, Stanley M, Krey Thomas, Keck Zhen-yong, Wang Wenyan, Rey, Felix A., Prentoe, Jannick, Arvind H Patel, Bukh Jens, Stanley M Lemon, Krey, T., Angela Ying-Jian Li, Felix A. Rey (171664), Foung, Steven K H, Thomas Krey (171661), Keck, Z., Xia Jinming, Krey, Thomas, Jinming Xia (171656), Stanley M. Lemon (30543), Wang, Wenyan, Lemon Stanley M., Patel Arvind H., Rey, Felix A, Li Angela Ying-Jian, Jinming Xia, Xia, Jinming, Foung, Steven K. H., Thomas Carlsen, Wang, W., Prentoe, J., Jens Bukh, Angela Ying-Jian Li (171663), Carlsen, T., Wang Yong   +68 more
core   +1 more source

Prediction of Long‐Term Prognosis in Patients With Hepatocellular Carcinoma Using the National Clinical Database Risk Calculator

Annals of Gastroenterological Surgery, EarlyView.
This study aimed to determine the value of the National Clinical Database (NCD) risk calculator in predicting surgical outcomes and long‐term prognosis in patients undergoing resection for hepatocellular carcinoma (HCC). We retrospectively analyzed data from 210 patients with HCC who underwent initial hepatic resection, assessing the relationship ...
Mariko Tsukagoshi, Kenichiro Araki, Norio Kubo, Takamichi Igarashi, Shunsuke Kawai, Kei Hagiwara, Kouki Hoshino, Ryo Muranushi, Ken Shirabe   +8 more
wiley   +1 more source

Unravelling the Hidden and Undiagnosed Cases of Hepatitis B and C Viruses among Patients Seeking Health Care for Other Viral Illness: A Cross-Sectional Study from Central India

Indian Journal of Community Medicine
Background: Chronic hepatitis B virus (HBV) and hepatitis C virus (HCV) infections pose a significant global public health burden. However, a substantial proportion of individuals remain undiagnosed, forming a hidden reservoir that perpetuates onward ...
Rajeev K. Jain, Anamika Jain, Shailendra K. Jain, Deepti Chaurasia, Ankita Agarwal, Harjeet S. Maan, Swati Jain, Nagaraj Perumal, Rakesh K. Shrivastava   +8 more
doaj   +1 more source

Preoperative FIB‐4 Index as a Potential Factor Associated With Severe Postoperative Complications and Endogenous Organ Failure After Hepatectomy for Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
This study demonstrates that a preoperative FIB‐4 index ≥ 5.0 independently predicts severe complications and endogenous organ failure (EOF) following hepatectomy for hepatocellular carcinoma. By capturing structural liver fragility and systemic vulnerability, the FIB‐4 index enhances surgical risk stratification beyond traditional functional markers ...
Masanori Nakamura, Yukiyasu Okamura, Osamu Aramaki, Nao Yoshida, Yusuke Mitsuka, Hayato Abe, Shunsuke Yamagishi, Yasuhiro Okumura, Kyongsun Pak, Shinobu Masuda   +9 more
wiley   +1 more source

Open-Heart Surgery and Viral Risk: Investigation of the Prevalence of HIV, HBV, and HCV in Patients Undergoing Heart Surgery [PDF]

Journal of Mazandaran University of Medical Sciences
Background and purpose: Bloodborne infectious diseases, particularly HBV, HCV, and HIV, are major global health concerns. Patients undergoing open-heart surgery are at a higher risk of infection due to the extensive use of injections and other invasive ...
Lotfollah Davoodi, Farhang Babamahmoodi, Seyed Morteza Taghavi, Kimia Torab Beygi, Sara Ghandi, Maryam Talebi Moghaddam   +5 more
doaj  

The distribution of hepatitis C virus genotypes in patients with hepatocellular carcinoma

Asian Journal of Medical Sciences, 2019
Background: Hepatic cirrhosis develops within 20-30 years in approximately 20% of individuals chronically infected with hepatitis C virus (HCV). Aims and Objective: This study aimed to determine the distribution of HCV genotypes in patients with HCV ...
Ayfer Bakır, Nuran Karabulut , Sema Alaçam, Barış Bakır , Ali Ağaçfidan   +4 more
doaj   +1 more source

Age- and sex-related reference ranges of alanine aminotransferase levels in children: European paediatric HCV network.

, 2009
BACKGROUND: Serum alanine aminotransferase (ALT) levels are commonly used to indicate liver damage. Although elevated levels indicate possible liver injury, abnormalities, or disease, some patients with "normal" ALT levels have minimal to mild liver ...
Newell, Marie-Louise, M. L. Newell, P. A. Tovo, G.V. Zuccotti, L. Pembrey, C. Thorne, Thorne, Claire, K. England, Pembrey, Lucy, England, Kirsty, Tovo, Pier-Angelo, European paediatric HCV network   +11 more
core   +1 more source

Mac‐2 Binding Protein Glycosylation Isomer (M2BPGi)–Based Risk Stratification Refined by Tumor Metabolic Activity in Hepatocellular Carcinoma

Annals of Gastroenterological Surgery, EarlyView.
M2BPGi reflects background liver fibrosis and hepatic functional impairment. PET SUVmax reflects tumor metabolic aggressiveness. Their combination identifies a dual‐high subgroup with the poorest recurrence‐free and overall survival. ABSTRACT Aim To evaluate the prognostic significance of preoperative Mac‐2 binding protein glycosylation isomer (M2BPGi)
Kojiro Shirabe, Junya Mita, Shinji Itoh, Takeo Toshima, Yoshiyuki Kitamura, Norifumi Iseda, Takuro Isoda, Kousei Ishigami, Tomoharu Yoshizumi   +8 more
wiley   +1 more source

The efficiency and safety of anti-Helicobacter pylori therapy in patients with concomitant chronic hepatitis C [PDF]

Терапевтический архив, 2016
Aim. To evaluate the efficiency and safety of two eradication therapy (ET) regimens for Helicobacter pylori infection in patients with concomitant chronic hepatitis C (CHC) in relation to the stage of liver fibrosis (LF). Subjects and methods.
D N Andreev, I V Maev, Yu A Kucheryavyi, D T Dicheva, E V Partsvania-vinogradova   +4 more
doaj  

Growth in the first 5 years of life is unaffected in children with perinatally-acquired hepatitis C infection

, 2005
Objectives To identify the effect of vertical hepatitis C virus (HCV) infection or exposure on growth in childhood. Study design Children (n = 1203) born to HCV-infected mothers were followed up from birth prospectively in centers of the European ...
FALDELLA, GIACOMO, England, K, . . . ], LANARI, MARCELLO, Pembrey, L, Newell, ML, EUROPEAN PAEDIATRIC HCV NETWORK: [. . .   +6 more
core   +1 more source