Pre-Existing HBV and HCV Infections Do Not Affect COVID-19-Related Outcomes: An Observational Retrospective Study [PDF]
, 2021 Viola Guardigni +6 more
openalex +1 more source
National Trends in Utilization and 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys.
Journal of the American Society of Nephrology, 2019 BACKGROUND Recent pilot trials have demonstrated the safety of transplanting HCV-viremic kidneys into HCV-seronegative recipients. However, it remains unclear if allograft function is impacted by donor HCV-viremia or recipient HCV-serostatus.
Vishnu S. Potluri +13 more
semanticscholar +1 more source
Structure‐Based Development of Ultra‐Broad‐Spectrum 3C‐Like Protease Inhibitors
Advanced Science, EarlyView.This study provides an in‐depth analysis of the substrate binding pocket of 3CLpros across all coronavirus species using bioinformatics and structural insights, revealing the critical impact of S2/S4 subsite diversity on the broad‐spectrum activity of approved therapeutics.
Haixia Su +15 more
wiley +1 more source
Risk Management and Healthcare Policy, 2021 Gizachew Beykaso,1,2 Andargachew Mulu,3 Mirutse Giday,1 Nega Berhe,1 Markos Selamu,2 Adane Mihret,3 Tilahun Teklehaymanot1 1Department of Molecular Biology and Immunology, Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa ...
Beykaso G +6 more
doaj
Development and characterization of a human monoclonal antibody for prevention of HCV recurrence in liver transplant patients [PDF]
, 2017 More than 170 million people worldwide are chronically infected with hepatitis C virus (HCV) and are at risk of developing liver fibrosis, cirrhosis and hepatocellular carcinoma.
Ball, Jonathan +11 more
core +1 more source
Integration of a geospatially targeted community-based testing approach with respondent-driven sampling to identify people who inject drugs living with HIV and HCV in Patti and Gorakhpur, India [PDF]
, 2023 Talia A. Loeb +6 more
openalex +1 more source
Advanced Science, EarlyView.Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang +14 more
wiley +1 more source
Unnatural Amino Acid and Emerging Chemistry Approaches to Map RNA–Protein Interactions
Angewandte Chemie, EarlyView.This review highlights emerging chemistries for mapping RNA–protein interactions, including genetically encoded unnatural amino acids, novel photocrosslinkers, and non‐photoactivatable crosslinking systems. We compare their mechanisms, reactivity and applications, outlining how these next‐generation tools enable higher‐resolution, site‐specific ...
Eryn Lundrigan +3 more
wiley +2 more sources
The Pan African Medical Journal, 2015 Viral hepatitis during pregnancy is associated with high risk of maternal complications and has become a leading cause of foetal death. So the main objective of this study is to determine the prevalence of hepatitis C viral infections among pregnant ...
Yohannes Zenebe +3 more
doaj +1 more source
The distribution of hepatitis C virus genotypes in patients with hepatocellular carcinoma
Asian Journal of Medical Sciences, 2019 Background: Hepatic cirrhosis develops within 20-30 years in approximately 20% of individuals chronically infected with hepatitis C virus (HCV). Aims and Objective: This study aimed to determine the distribution of HCV genotypes in patients with HCV ...
Ayfer Bakır +4 more
doaj +1 more source