Results 101 to 110 of about 425,993 (391)
Mechanism of Lenvatinib Resistance via Exosomal miRNA‐132/Nrf2 Axis in Hepatocellular Carcinoma
Annals of Gastroenterological Surgery, EarlyView.Exosomal miRNA‐132 from LVT‐res HCC cells activated Nrf2 expression through the PTEN/GSK3β pathway in recipient cells. This cascade could induce drug resistance in non‐resistant HCC cells in the TME. ABSTRACT Introduction Lenvatinib is a multiple receptor tyrosine kinase inhibitor and a first‐line targeted therapy for hepatocellular carcinoma (HCC ...
Chie Takasu +7 more
wiley +1 more source
Romanian Journal of Laboratory Medicine, 2017 Introduction. The past years have revolutionized the treatment of hepatitis C virus (HCV) infection, with high rates of sustained virologic response (SVR). Furthermore, liver fibrosis has recently been redefined as a dynamic, reversible process. Methods.
Nițescu Maria +6 more
doaj +1 more source
Estimating the cost-effectiveness of detecting cases of chronic hepatitis C infection on reception into prison [PDF]
, 2006 Background In England and Wales where less than 1% of the population are Injecting drug users (IDUs), 97% of HCV reports are attributed to injecting drug use. As over 60% of the IDU population will have been imprisoned by the age of 30 years, prison may
AJ Sutton +24 more
core +5 more sources
Clinical Infectious Diseases, 2016 Epidemiological data and modeling suggest a continuing hepatitis C virus (HCV) epidemic among human immunodeficiency virus-diagnosed men who have sex with men in the United Kingdom.
N. Martin +12 more
semanticscholar +1 more source
HCV and cryoglobulinemic vasculitis.
Cleveland Clinic Journal of Medicine, 2002 munoglobulinemia)or more immunoglobulins (mixedcryoglobulinemia), which precipitate at temperaturesbelow 37 °C and redissolve on re-warming is termed“cryoglobulinemia.” This is an in vitro phenomenon; theactual mechanism(s) of cryoprecipitation remains obscure.It could be secondary to intrinsic characteristics ofboth mono- and polyclonal immunoglobulin
FERRI, Clodoveo +9 more
openaire +6 more sources
Annals of Gastroenterological Surgery, EarlyView.Sequential hepatic vein embolization (HVE) following portal vein embolization (PVE) significantly improves both the volume and function of the future remnant liver (FRL) compared to PVE alone. In this study, the FRL regeneration rates for volume and function were markedly higher and faster in the PVE–HVE group, with no differences in surgical outcomes ...
Thanh Tung Lai +9 more
wiley +1 more source
Development and characterization of a human monoclonal antibody for prevention of HCV recurrence in liver transplant patients [PDF]
, 2017 More than 170 million people worldwide are chronically infected with hepatitis C virus (HCV) and are at risk of developing liver fibrosis, cirrhosis and hepatocellular carcinoma.
Ball, Jonathan +11 more
core +1 more source
Persistent hepatitis C virus infection in vitro: coevolution of virus and host. [PDF]
, 2006 The virological and cellular consequences of persistent hepatitis C virus (HCV) infection have been elusive due to the absence of the requisite experimental systems.
Cheng, Guofeng +7 more
core +3 more sources
Exonic Variation and Its Clinical Impact in 7221 Old Order Amish
American Journal of Medical Genetics Part A, EarlyView.ABSTRACT The Amish of Lancaster County, PA has been the focus of genetic studies for many years due to its demographic history and unique genetic makeup that includes a historical bottleneck event and subsequent genetic drift, resulting in a marked decrease in genetic diversity and increased frequency of some variants that have substantially shaped the
Braxton D. Mitchell +21 more
wiley +1 more source
Pakistan Armed Forces Medical Journal, 2020 Objective: To determine the rates of HCV seroconversion in patients undergoing hemodialysis (HD) in dialysis units of tertiary care hospitals. Study Design: Descriptive cross-sectional study.
Muhammad Asif +5 more
doaj