Liver transplantation for hepatitis C virus (HCV) non‐viremic recipients with HCV viremic donors
American Journal of Transplantation, 2018 In the context of organ shortage, the opioid epidemic, and effective direct‐acting antiviral (DAA) therapy for hepatitis C virus (HCV), more HCV‐infected donor organs may be used for liver transplantation.
A. Kwong +6 more
semanticscholar +1 more source
Advances in miRNA research: Unraveling the complexities of gene regulation
Animal Models and Experimental Medicine, EarlyView.Overview of miRNA‐mediated regulation in key biological processes. This illustration offers a comprehensive view of the diverse functions that microRNAs perform in governing various biological processes, highlighting their profound significance within the complex web of gene expression and cellular function.
Jiawei Zheng, Guoqing Zhang, Linzhu Ren
wiley +1 more source
Timing for treatment of HCV recurrence after liver transplantation: the earlier the better. [PDF]
, 2016 HCV is the leading cause of death from liver disease and is the most common indication for a liver transplantation. Although HCV is a widespread health problem, disease management is particularly challenging in several key subpopulations, including liver
Burra, Patrizia +2 more
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Strategies to induce broadly protective antibody responses to viral glycoproteins
Expert Review of Vaccines, 2017 Introduction: Currently, several universal/broadly protective influenza virus vaccine candidates are under development. Many of these vaccines are based on strategies to induce protective antibody responses against the surface glycoproteins of ...
F Krammer
doaj +1 more source
Recombinant Flag-tagged E1E2 glycoproteins from three hepatitis C virus genotypes are biologically functional and elicit cross-reactive neutralizing antibodies in mice [PDF]
, 2018 Hepatitis C virus (HCV) is a globally disseminated human pathogen for which no vaccine is currently available. HCV is highly diverse genetically and can be classified into 7 genotypes and multiple sub-types. Due to this antigenic variation, the induction
Bieńkowska-Szewczyk, Krystyna +5 more
core +1 more source
Association of Codon 72 of P53 Gene Polymorphism with Chronic Hepatitis C Virus Infection: A Case Control Study [PDF]
Journal of Cell and Molecular Research, 2016 Single nucleotide polymorphism in codon 72 of p53 gene (Arg/Pro) changes p53 protein structure and affects its activities. Hepatitis C virus (HCV) is believed to induce hepatocellular carcinoma and P53 polymorphisms have been associated with human ...
Sina Gerayli +8 more
doaj +1 more source
Hepatitis C Virus and Hepatocellular Carcinoma: Pathogenetic Mechanisms and Impact of Direct-Acting Antivirals [PDF]
, 2018 INTRODUCTION: Globally, between 64 and 103 million people are chronically infected with Hepatitis C virus (HCV), with more than 4.6 million people in the United States and is associated with more than 15.000 deaths annually.
Petruzziello, Arnolfo +5 more
core +1 more source
National Trends in Utilization and 1-Year Outcomes with Transplantation of HCV-Viremic Kidneys.
Journal of the American Society of Nephrology, 2019 BACKGROUND Recent pilot trials have demonstrated the safety of transplanting HCV-viremic kidneys into HCV-seronegative recipients. However, it remains unclear if allograft function is impacted by donor HCV-viremia or recipient HCV-serostatus.
Vishnu S. Potluri +13 more
semanticscholar +1 more source
Built-in bias in HCV clearance in acute HCV infection
Journal of Hepatology, 2014 To the Editor:We read with interest the recent paper about hepatitis C virus(HCV) clearance in patients with acute HCV infection [1].Weare wondering why authors did not calculate risk ratio insteadof odds ratio (OR) when they have run a cohort study? Theycan present how much is the incidence of HCV clearance and rel-ative risk (RR) of factors affecting
Ali Kabir, Davood Khalili
openaire +3 more sources