Results 251 to 260 of about 210,178 (301)

HCV and Autoimmunity

Current Pharmaceutical Design, 2008
Hepatitis C virus (HCV) infection is characterized by a number of autoreactive manifestations, such as autoantibody production, cryoglobulinemia and thyroid disorders. We will analyse critically the mechanisms invoked, and partially documented, to explain such manifestations arising in genetically predisposed individuals exposed to HCV.
FERRI, SILVIA, MURATORI, LUIGI, LENZI, MARCO, GRANITO, ALESSANDRO, BIANCHI, FRANCESCO BIANCO, Vergani D.   +5 more
openaire   +2 more sources

CCR5Δ32 in HCV infection, HCV/HIV co-infection, and HCV-related diseases

Infection, Genetics and Evolution, 2018
Although a potential involvement of the CCR5Δ32 variant has already been suggested in relation to susceptibility to hepatitis C virus (HCV) infection, data from the literature is still quite controversial. Thus, our study evaluated the influence of the CCR5Δ32 allele variant in HCV infection, HCV/HIV co-infection, and HCV-related diseases in ...
Chies Ja, Valverde-Villegas Jm, Ellwanger Jh   +2 more
exaly   +3 more sources

Lipids and HCV

Seminars in Immunopathology, 2012
Chronic hepatitis C virus (HCV) infection is associated with an increase in hepatic steatosis and a decrease in serum levels of total cholesterol, low-density lipoprotein cholesterol (LDL) and apolipoprotein B (apoB), the main protein constituent of LDL and very low-density lipoprotein (VLDL).
M F, Bassendine, D A, Sheridan, S H, Bridge, D J, Felmlee, R D G, Neely   +4 more
openaire   +2 more sources

Inhibition of HCV Replication in HCV Replicon by shRNAs

Nucleosides, Nucleotides and Nucleic Acids, 2006
We show that the vector-derived long dsRNA specifically inhibits the replication of HCV RNA in HCV replicon. We designed a long dsRNA targeted to the full-length HCV IRES/core elements (1-to 377-nt). Our results revealed that the replication of HCV RNA was reduced to near background levels in a sequence-specific manner by the long dsRNAs in the HCV ...
Hiroyuki, Hamazaki, Hitoshi, Takahashi, Kunitada, Shimotohno, Naoko, Miyano-Kurosaki, Hiroshi, Takaku   +4 more
openaire   +2 more sources

HCV seroreactivity and detection of HCV RNA in cirrhotics

Diagnostic Microbiology and Infectious Disease, 1999
This study was carried out to determine the presence of HCV infection in cirrhotic patients and to compare their serologic profiles with detection of HCV RNA by RT-PCR. Liver function profiles were assessed and correlated with infection. Coinfection of HCV with HBV was studied in the Indian context Sera from 62 patients of biopsy confirmed cirrhosis ...
N, Berry, A, Chakravarti, U, Das, P, Kar, B C, Das, M D, Mathur   +5 more
openaire   +2 more sources

HCV and Cryoglobulinemia

2004
Discussion of the etiologic role of HCV in mixed ...
FERRI, Clodoveo, Bombardieri S.
openaire   +2 more sources

Lymphocyte Subsets in Hemodialyzed HCV+ and HCV– Patients

Nephron, 1998
The aim of our study was to get information on the immune status of patients who undergo haemodialysis in the presence of an HCV infection. This virus infects not only hepatocytes, but also blood mononuclear cells, in particular B cells [1], but we do not know the role of this lymphocyte involvement in the maintenance and progression of hepatitis.
S, Cucciaioni, L, Pellegrini, L, Giombini, U, Buoncristiani, P, Tacconi, M L, Vatteroni, F, Bruschi   +6 more
openaire   +2 more sources

HBV/HCV Coinfection in the Era of HCV-DAAs

Clinics in Liver Disease, 2019
Epidemiologic studies suggest that 10% to 15% of patients infected with hepatitis C virus (HCV) are coinfected with hepatitis B virus (HBV) in the United States as a result of the shared modality of transmission, but the true prevalence is not known.
Rashed, Abdelaal, Beshoy, Yanny, Mohamed, El Kabany   +2 more
openaire   +2 more sources

Chronic HCV infection is a risk of atherosclerosis. Role of HCV and HCV-related steatosis

Atherosclerosis, 2012
HCV and NAFLD are associated with atherosclerosis in general population. The prevalence of atherosclerosis in chronic hepatitis C (CHC) patients is unknown. We hypothesized that HCV per se and HCV-related steatosis could favour atherosclerosis. Thus, in CHC patients we assessed: (a) the prevalence of atherosclerosis; (b) the role of HCV, cardio ...
ADINOLFI, Luigi Elio, Restivo L, ZAMPINO, Rosa, Guerrera B, Lonardo A, Ruggiero L, Riello F, Loria P, FLORIO, Anna   +8 more
openaire   +3 more sources

Vertical transmission of HCV

Acta Obstetricia et Gynecologica Scandinavica, 1998
Knowledge about vertical transmission of HCV is still limited. In this study we followed up the virological status of a series of offspring born to anti-HCV positive, anti-HIV negative mothers.Between January 1993 and January 1995, 5000 consecutive, anti-HIV negative pregnant women were screened for anti-HCV (ELISA III) and all positive samples were ...
A. La Torre, R. L. Biadaioli, T. Capobianco, M. Colao, MONTI, MONICA, F. Pulli, C. Visioli, ZIGNEGO, ANNA LINDA, RUBALTELLI, FIRMINO FRANCESCO   +8 more
openaire   +3 more sources