Results 71 to 80 of about 425,993 (391)

Evaluating the utility of public-facing jail registers to inform public health practice, Washington state 2023

open access: yesBMC Public Health
Background Data on criminal justice system involvement can support public health efforts in ways that have been recognized for decades, but data protections and jurisdictional boundaries can make data sharing difficult.
Steven Erly   +6 more
doaj   +1 more source

Prevalence of transfusion-transmitted infections among blood donors in Koforidua, Ghana, 2016

open access: yesJournal of Interventional Epidemiology and Public Health
Introduction: Transfusion-transmitted infections (TTIs) are infections of public health concern since they have the potential to be transferred from person to person through blood transfusion. This study determined the prevalence of HIV, HBV, HCV, and
Holy Alomatu   +6 more
doaj   +1 more source

Evaluation of the Prevalence of Incidental HBV, HCV and HIV Infection Among Patients Presenting to the Emergency Department: A Prospective Cross-sectional Study

open access: yesEurasian Journal of Emergency Medicine, 2020
Aim:In this study, we randomized the patients without known hepatitis-B, hepatitis C and HIV infection who presented to the emergency department (ED).
Mehmet Murat Oktay   +6 more
doaj   +1 more source

Changes in DNA methylation profile in liver tissue during progression of HCV-induced fibrosis to hepatocellular carcinoma

open access: yesВавиловский журнал генетики и селекции, 2023
In this study we compared methylation levels of 27,578 CpG sites between paired samples of the tumor and surrounding liver tissues with various degrees of damage (fibrosis, cirrhosis) in HCV-induced hepatocellular carcinoma (HCC) patients, as well as ...
I. A. Goncharova   +4 more
doaj   +1 more source

Efficacy of 8 Weeks of Sofosbuvir, Velpatasvir, and Voxilaprevir in Patients With Chronic HCV Infection: 2 Phase 3 Randomized Trials.

open access: yesGastroenterology, 2017
BACKGROUND & AIMS Patients with chronic hepatitis C virus (HCV) infection have high rates of sustained virologic response (SVR) after 12 weeks of treatment with the nucleotide polymerase inhibitor sofosbuvir combined with the NS5A inhibitor velpatasvir ...
Ira M. Jacobson   +29 more
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Modular Synthesis of Pyritide‐Inspired Macrocycles Featuring Bipyridine Motifs

open access: yesAngewandte Chemie, EarlyView.
A pyritide‐inspired build/couple/pair strategy yields a diverse macrocycle library. This approach expands chemical space and enables the discovery of 6paW, a potent anti‐ferroptotic agent. Abstract Macrocycles represent a promising class of drug‐like scaffolds with unique structural features and the ability to engage challenging targets such as protein–
Ji Hyae Lee   +4 more
wiley   +2 more sources

Burden and Transmission Risks of Viral Hepatitis in Southern Ethiopia: Evidence Needed for Prevention and Control Measures

open access: yesRisk Management and Healthcare Policy, 2021
Gizachew Beykaso,1,2 Andargachew Mulu,3 Mirutse Giday,1 Nega Berhe,1 Markos Selamu,2 Adane Mihret,3 Tilahun Teklehaymanot1 1Department of Molecular Biology and Immunology, Aklilu Lemma Institute of Pathobiology, Addis Ababa University, Addis Ababa ...
Beykaso G   +6 more
doaj  

Evaluate the prevalence of CCP and RF antibodies as a marker for diagnosis and progression of Rheumatoid Arthritis disease and assess the prevalence of HCV in RA patients [PDF]

open access: yesمجلة جامعة الانبار للعلوم الصرفة, 2014
Rheumatoid arthritis (RA) is a chronic inflammatory autoimmune disease characterized by the presence of autoantibodies like rheumatoid factor (RF). In the last few years, several other autoantibodies have been described of which anti-cyclic citrullinated
Qabas R. Ali   +3 more
doaj   +1 more source

Ferritin heavy chain Is the host factor responsible for HCV-Induced inhibition of apoB-100 production and is required for efficient viral infection [PDF]

open access: yes, 2012
Hepatic fat export occurs by apolipoprotein B-100-containing lipoprotein production, whereas impaired production leads to liver steatosis. Hepatitis C virus (HCV) infection is associated to dysregulation of apoB-100 secretion and steatosis; however, the ...
AMICONE, Laura   +9 more
core   +3 more sources

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