Results 71 to 80 of about 276,656 (346)

Anisotropic Surface Microrollers for Endovascular Navigation: A Computational Analysis with a Case Study in Hepatic Perfusion

Advanced Theory and Simulations, EarlyView.
Computational fluid dynamics analyses assess the upstream locomotion performance of anisotropic microrollers with varying height‐to‐width ratios. Observing their successful upstream locomotion in veins, their performance in hepatic circulation is investigated for treating primary liver cancer.
Burak Arslan, Ugur Bozuyuk, Kıvanç Görgülü, Erdost Yildiz, Hakancan Ozturk, Lucia Liotta, Volker Heinemann, Hana Algül, Metin Sitti   +8 more
wiley   +1 more source

ASSOCIATION BEETWEEN IL-28β POLYMORPHISMS AND EFFECTIVENESS OF CONCOMITANT THERAPY OF HIV INFECTION IN PATIENTS WITH HCV/HIV CO-INFECTION DURING THE ANTIVIRAL THERAPY

Инфекция и иммунитет, 2014
. The aim of the study was  to evaluate the associations between the polymorphism rs8099917 IL-28β and changing of HIV viral load and the effectiveness of high active antiretroviral therapy during the treatment of chronic hepatitis C in HIV-infected ...
E. S. Kovaleva
doaj   +1 more source

Advances in Single‐Cell Sequencing for Infectious Diseases: Progress and Perspectives

Advanced Science, EarlyView.
Single‐cell sequencing technologies uncover novel, unknown, and emergent features of many diseases. This review describes recent progress of single‐cell sequencing technologies and their applications in infectious diseases, summarizes the underlying commonalities of different infections and discusses future research directions, facilitating the ...
Mengyuan Lyu, Yang Liu, Jian Zhou, Hongli Lai, Hongxia Ruan, Dongsheng Wu, Shun Zhu, Xudong Zhou, Wananqi Ma, Yuchen Huang, Shuting Lei, Han Luo, Jie Chen, Binwu Ying   +13 more
wiley   +1 more source

Non-invasive quantification of liver fibrosis regression following successful treatment of chronic hepatitis C with direct acting antivirals

Romanian Journal of Laboratory Medicine, 2017
Introduction. The past years have revolutionized the treatment of hepatitis C virus (HCV) infection, with high rates of sustained virologic response (SVR). Furthermore, liver fibrosis has recently been redefined as a dynamic, reversible process. Methods.
Nițescu Maria, Vâjâitu Cristina, Săndulescu Oana, Streinu-Cercel Adrian, Pițigoi Daniela, Preoțescu Liliana Lucia, Streinu-Cercel Anca   +6 more
doaj   +1 more source

Trial of Transplantation of HCV-Infected Kidneys into Uninfected Recipients.

New England Journal of Medicine, 2017
An open-label pilot trial involving 10 patients shows that hepatitis C virus genotype 1–infected kidneys transplanted into HCV-negative recipients, followed by direct-acting antiviral therapy, can result in excellent allograft function with cure of HCV ...
David S. Goldberg, Peter L. Abt, Emily A. Blumberg, V. V. Van Deerlin, M. Levine, K. Rajender Reddy, Roy D. Bloom, Susanna M. Nazarian, D. Sawinski, P. Porrett, A. Naji, R. Hasz, Lawrence Suplee, J. Trofe‐Clark, A. Sicilia, M. McCauley, M. Farooqi, C. Gentile, Jennifer R. Smith, Peter P. Reese   +19 more
semanticscholar   +1 more source

Exosomes From Intestinal Epithelial Cells Promote Hepatic Differentiation of Liver Progenitor Cells in Gut‐Liver‐on‐a‐Chip Models

Advanced Science, EarlyView.
The effects of intestinal epithelial cells and their exosomes on the hepatic differentiation of HPCs are explored in a gut‐liver‐on‐a‐chip. Exosomes from intestinal epithelial cells improve liver fibrosis. Moreover, the miR‐371‐373 cluster in the exosomes may mediate this effect by regulating the hepatic differentiation of HPCs.
Liang Ye, Shi Li, Guofang Bi, Binghui Li, Zhai Cai, Meixian Jin, Ying Zhang, Wanren Yang, Yang Li, Shao Li, Wei Hu, Yi Gao, Mingxin Pan, Shuqin Zhou, Chao Zhang, Huichang Bi, Qing Peng   +16 more
wiley   +1 more source

The hepatitis C epidemic in Canada: An overview of recent trends in surveillance, injection drug use, harm reduction and treatment

Canada Communicable Disease Report, 2021
Hepatitis C continues to be a significant public health concern in Canada, with the hepatitis C virus (HCV) responsible for more life-years lost than all other infectious diseases in Canada.
Lillian Lourenço, Marian Kelly, Jill Tarasuk, Kyla Stairs, Maggie Bryson, Nashira Popovic, Josephine Aho   +6 more
doaj   +1 more source

Recommendations for Prevention and Control of Hepatitis C Virus (HCV) Infection and HCV-Related Chronic Disease

, 1998
M. Alter, H. Margolis
openalex   +3 more sources

Prevalence of HCV and Its Correlation with HCV Genotypes

European Journal of Medical and Health Sciences, 2021
Introduction: Hepatitis C virus is known to cause liver inflammation, which may progress to liver cirrhosis and hepatocellular carcinoma. The genomes of HCV display sequence heterogenicity, thus, are classified in different genotypes and subtypes. Genotyping aids in understanding the epidemiology, biological features of the virus and inspecting the ...
Salil Vaniawala, Khushboo Daryani, Monika Patel, Pankaj Kumar Gadhia   +3 more
openaire   +3 more sources

NSP7 Molecular Degrader Attenuates Coronaviral Infection Through the β‐TrCP1/FBXO5 Axis

Advanced Science, EarlyView.
Host E3 ligase FBXO5 as a key regulator that promotes K48‐linked ubiquitination and proteasomal degradation of SARS‐CoV‐2 NSP7, thereby suppressing viral replication. NSP7 ubiquitination is co‐regulated by β‐TrCP1 and TAF1. Small molecule BC24877 disrupts β‐TrCP1‐mediated degradation of FBXO5, stabilizing FBXO5 and enhancing NSP7 clearance ...
Yao Tong, Travis B. Lear, Ferhan Tuncer, John J. Villandre, Áine N. Boudreau, Bo Lin, Irene Alfaras, Jason R. Kennerdell, Daniel P. Camarco, Mads B. Larsen, Yun Hua, Yanwen Chen, Meigin E. Chandler, Ricardo Pineda, Simon M. Barratt‐Boyes, John W. Evankovich, Toren Finkel, Yuan Liu, Bill B. Chen   +18 more
wiley   +1 more source