Results 211 to 220 of about 116,207 (325)

Epigenetic modifications regulate peg elongation and underground fruiting in peanut in response to environmental cues

open access: yesThe Plant Genome, Volume 19, Issue 1, March 2026.
Abstract Epigenetic regulation plays a central role in coordinating peanut (Arachis hypogaea L.) fruit pegging, a unique developmental process in which fertilized ovaries transition from aerial growth to subterranean pod formation. This review synthesizes current evidence demonstrating that dynamic interactions among DNA methylation, histone ...
Yohannes Gelaye, Huaiyong Luo
wiley   +1 more source

Histone deacetylases in Duchenne muscular dystrophy: a role in the mechanism of disease and a target for inhibition. [PDF]

open access: yesClin Epigenetics
Bertoldi M   +9 more
europepmc   +1 more source

The Prebiotic and Techno‐Functional Potential of Microbial Exopolysaccharides for Human Health and Food Systems

open access: yesComprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 2, March 2026.
ABSTRACT Microbial exopolysaccharides (EPS) represent a diverse class of biopolymers holding considerable promise as functional food ingredients. This review analyzes the dual function of microbial EPS as a candidate for prebiotic agents and techno‐functional additives.
Md. Abdur Razzak   +7 more
wiley   +1 more source

RB1 inactivation in cutaneous carcinomas

open access: yesHistopathology, Volume 88, Issue 4, Page 769-789, March 2026.
Among skin carcinomas, recurrent RB1 inactivation is observed in Merkel cell carcinoma, in a subset of squamous cell carcinoma with bowenoid morphology, in sebaceous carcinoma and in the recently described Wnt/beta‐catenin rosette‐forming carcinoma.
Tiffany Liv   +8 more
wiley   +1 more source

Design, Synthesis, and Biological Evaluation of Pseudo‐Natural Products Inspired by Aryloctahydroindole Alkaloids

open access: yesChemMedChem, Volume 21, Issue 3, 12 February 2026.
Mesembrine alkaloid pseudo‐natural products were synthesized employing a microwave‐assisted Diels–Alder reaction as a key step. Morphological profiling by cell painting revealed compound‐topology‐dependent mitochondrial fragmentation or inhibition of respiration.
Luca C. Greiner   +6 more
wiley   +1 more source

Cancer Stem Cells Shift Metabolite Acetyl‐Coenzyme A to Abrogate the Differentiation of CD103+ T Cells

open access: yesAdvanced Science, Volume 13, Issue 8, 9 February 2026.
Lei et al. demonstrate that cancer stem cells (CSCs) play a pivotal role in impairing the differentiation of CD103+ T cells in patients with non‐small‐cell lung cancer. The key mechanism involves CSC‐derived acetyl‐CoA, which disrupts CD103+ T cell differentiation by sequentially inducing acetylation and ubiquitination of the Blimp‐1 protein. Targeting
Jiaxin Lei   +10 more
wiley   +1 more source

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