Traction Force Microscopy for Viscoelastic Substrates: A Semi‐Analytical Method
Advanced Science, EarlyView.A semi‐analytical viscoelastic traction force microscopy framework is introduced for quantifying time‐resolved cell tractions on flat finite‐thickness substrates. The method generalizes elastic traction force microscopy to Generalized Maxwell materials, identifies when elastic approximations remain valid and, when they do not, shows that inferred ...
Adrià Villacrosa‐Ribas +10 more
wiley +1 more source
A Portable and Dual‐Button Microneedle Device Enables Intelligent Multimodal Laser Sensing
Advanced Science, EarlyView.A portable and dual‐button microneedle device enables rapid interstitial fluid sampling. Coupled with multimodal laser sensing and AI‐assisted data processing, the platform enables simultaneous molecular and elemental analysis for minimally invasive and multiplexed health assessment toward point‐of‐care diagnostics.
Yuanchao Liu +12 more
wiley +1 more source
Multiple Instances QoS Routing in RPL: Application to Smart Grids
Sensors, 2018 The Smart Grid (SG) aims to transform the current electric grid into a “smarter” network where the integration of renewable energy resources, energy efficiency and fault tolerance are the main benefits. This is done by interconnecting every energy source,
Jad Nassar +5 more
doaj +1 more source
The Medium Cut-Off Membrane Does Not Lower Protein-Bound Uremic Toxins
Toxins, 2022 The accumulation of protein-bound uremic toxins (PBUT) is associated with increased cardiovascular outcomes in patients on dialysis. However, the efficacy of PBUT removal for a medium-cutoff (MCO) membrane has not been clarified.
Yang Gyun Kim +8 more
doaj +1 more source
Ciclopirox Olamine Inhibits the NLRP3 Inflammasome to Alleviate Inflammatory Diseases
Advanced Science, EarlyView.There is no drug targeting the NLRP3 inflammasome that has been approved for use in clinical settings. Ciclopirox olamine (CPX), an antifungal agent approved by the US Food and Drug Administration (FDA), is identified as a specific and potent NLRP3 inflammasome inhibitor. CPX targets the NACHT domain of NLRP3 at Y381 to impair NLRP3 oligomerization and
Xinyu Xia +7 more
wiley +1 more source
Frontiers in Physiology, 2022 PurposeSites of highest dominant frequency (HDF) are implicated by many proposed mechanisms underlying persistent atrial fibrillation (persAF). We hypothesized that prospectively identifying and ablating dynamic left atrial HDF sites would favorably ...
Gavin S. Chu +15 more
doaj +1 more source
Advanced Science, EarlyView.We screened 558 reverse transcriptases and engineered an optimized rat endogenous retrovirus‐derived variant, enRERV‐RT, via structure‐guided engineering and deep mutational scanning. This enhanced prime editor, based on the engineered RT, outperforms conventional M‐MLV‐RT systems across plant and animal cells, particularly at hard‐to‐edit loci ...
Linsha Ma +22 more
wiley +1 more source
The Changing Character of Carbon in Fluids with Pressure
Geophysical Monograph Series, Page 259-269., 2020 This book is Open Access. A digital copy can be downloaded for free from Wiley Online Library.
Explores the behavior of carbon in minerals, melts, and fluids under extreme conditions
Carbon trapped in diamonds and carbonate-bearing rocks in subduction zones are examples of the continuing exchange of substantial carbon ...
Dimitri Sverjensky +2 more
wiley +1 more source
Penser le modèle d’enseignement pratiqué dans les écoles primaires en Tunisie
Langues & CulturesSans prétendre être une recherche exhaustive sur le travail enseignant, cet article vise à mettre en évidence la part des prescriptions et des savoirs formels dans le modèle d’enseignement pratiqué dans le premier degré en Tunisie.
Habib HADJ AMOR
doaj +1 more source
Advanced Science, EarlyView.A hybrid biomechanical–electromagnetic energy‐harvesting e‐skin is developed using a gelatin‐based outer matrix with a zwitterionic conductive inner layer. The e‐skin autonomously generates stable electrical stimulation from daily body motion and ambient electronics, enabling significantly enhanced wound healing bothin vitro and in vivo.
Syun‐Hong Chou +12 more
wiley +1 more source