Results 71 to 80 of about 16,285 (241)

Sema4A neutralization reduces fibrosis and inflammation in a mouse model of systemic sclerosis and a 3D model of immunity‐driven fibrosis

Arthritis &Rheumatology, Accepted Article.
Objective We previously showed that Semaphorin4A (Sema4A) is elevated in patients with systemic sclerosis (SSc) and promotes inflammation and fibrosis in vitro. Here, we examined the effect of Sema4A neutralization in vivo and in 3D fibrosis models. Methods Sema4A plasma levels were measured by ELISA in healthy controls (n=31) and patients with SSc (n=
Jaime Marty, Sara Martinez‐Ramos, Carlos Rafael‐Vidal, Beatriz Malvar‐Fernández, Tiago Carvalheiro, Ralph G. Tieland, Ines Ramos, Wiola Marut, Ana Pinheiro‐Lopes, Ana Argibay, Brenda Maure, Caritina Vázquez‐Triñanes, Nair Pérez Gómez, David Fernández‐Fernández, Sandra Vila, Coral Mouriño, Rogier M Thurlings, Arjan van Caam, Alberto Rivera, José María Pego‐Reigosa, Timothy R. Radstake, Samuel Garcia   +21 more
wiley   +1 more source

Comparison of left ventricular hemodynamic forces measured by transthoracic echocardiography and cardiac magnetic resonance imaging in healthy adults

Scientific Reports
Hemodynamic forces (HDF), which reflect the forces exchanged between blood and cardiac tissues, can be derived from cardiac magnetic resonance (CMR) or transthoracic echocardiography (TTE).
Aizhan Zhankorazova, Giovanni Tonti, Zaukiya Khamitova, Bauyrzhan Toktarbay, Dinara Jumadilova, Makhabbat Bekbossynova, Nail Khissamutdinov, Tairkhan Dautov, Alessandro Salustri   +8 more
doaj   +1 more source

Mechanistic models for intermittent haemodialysis and haemodiafiltration clearance

British Journal of Clinical Pharmacology, EarlyView.
Haemodialysis has been used clinically for more than 70 years, but data regarding the clearance of medicines during dialysis are often based on studies with outdated, less efficient dialysers. Moreover, dialysis clearance is still frequently estimated using empirical approaches which lack mechanistic interpretability, are not readily generalizable ...
Laila Nassar, Nick Holford, Daniel Kurnik   +2 more
wiley   +1 more source

HDF: Hybrid deep features for scene image representation

, 2020
HDF: Hybrid deep features for scene image ...
Xuequan Lu (2318185), Yong Xiang (13101027), Chiranjibi Sitaula (12152416), Anish Basnet (13426755), Sunil Aryal (13096509)   +4 more
core  

Gene expression profile using young HDF donors as the control.

, 2019
Gene expression profile using young HDF donors as the control.
Juliana Carvalhães Lago (317685), Maria Beatriz Puzzi (6911855)   +1 more
core   +1 more source

Use of Amniotic Microparticles Coated with Fibroblasts Overexpressing SDF-1a to Create an Environment Conducive to Neovascularization for Repair of Full-Thickness Skin Defects

Cell Transplantation, 2016
As angiogenesis and vasculogenesis involve the complex network structures of various types of cells, extracellular matrix components, and cytokines, it is still difficult to exactly mimic the microenvironment of vascularization in vivo.
Yun-Qing Zhang, Shi-Zhao Ji, He Fang, Yong-Jun Zheng, Peng-Fei Luo, Hai-Bin Wu, Min-Juan Wu, Zhi-Hong Wang, Shi-Chu Xiao, Zhao-Fan Xia   +9 more
doaj   +1 more source

Advances in vital‐sign prediction and early‐warning models for underground coal mine workers integrating environmental factors

Deep Underground Science and Engineering, EarlyView.
This review synthesizes advances in predicting miners' vital signs by integrating environmental monitoring (dust, temperature, and gas) with physiological data. It highlights multi‐source data fusion techniques and early‐warning models for enhanced occupational safety in underground coal mines.
Junji Zhu, Dawei Cui, Yingjie Liu, Yuntao Liang, Yue Zhang   +4 more
wiley   +1 more source

The risk for infectious events in patients treated with HD and HDF

, 2015
HDF = Online hemodiafiltration; HD = Low-flux hemodialysis; No. = number; FU = follow-up; HR = hazard ratio¶ analyzed with Cox for repeated events^obtained through unadjusted Cox proportional hazards models, time to (first) infectious event*On treatment ...
Peter J. Blankestijn (151363), Albert H. A. Mazairac (151352), Piet M. ter Wee (151365), Marinus A. van den Dorpel (151350), Michiel L. Bots (50180), E. Lars Penne (151356), Renée Levesque (404609), Claire H. den Hoedt (151351), Neelke C. van der Weerd (151348), Menso J. Nubé (151354), Muriel P. C. Grooteman (151349), Ingeborg van der Tweel (18182)   +11 more
core   +1 more source

Analysis of 2-Year Survival Outcomes of Japanese Older Populations on Hemodiafiltration: A Propensity Score-Matched Study Based on Insurance Claims Data

Kidney and Dialysis
Despite the lack of evidence that suggests hemodiafiltration (HDF) offers a better survival outcome than standard hemodialysis (HD), the number of patients initiating HDF in Japan continues to rise.
Aziz Jamal, Akira Babazono, Ning Liu, Takako Fujita, Sung-a Kim, Yunfei Li   +5 more
doaj   +1 more source

Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis

ESC Heart Failure, Volume 12, Issue 2, Page 1358-1373, April 2025.
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen, Jiahao Shi, Yue Wu, Lizhu Miao, Zilin Wang, Yixuan Wang, Siwei Xu, Yu Lou   +7 more
wiley   +1 more source