Results 11 to 20 of about 5,136 (200)

Stereoisomer-specific ginsenoside 20(S)-Rg3 reverses replicative senescence of human diploid fibroblasts via Akt-mTOR-Sirtuin signaling

open access: yesJournal of Ginseng Research, 2020
Background: The replicative senescence of human dermal fibroblasts (HDFs) is accompanied by growth arrest. In our previous study, the treatment of senescent HDFs with Rg3(S) lowered the intrinsic reactive oxygen species (ROS) levels and reversed cellular
Kyeong-Eun Yang   +7 more
doaj   +1 more source

BlockHDFS: Blockchain-integrated Hadoop distributed file system for secure provenance traceability

open access: yesBlockchain: Research and Applications, 2021
Hadoop Distributed File System (HDFS) is one of the widely used distributed file systems in big data analysis for frameworks such as Hadoop. HDFS allows one to manage large volumes of data using low-cost commodity hardware.
Viraaji Mothukuri   +4 more
doaj   +1 more source

The Paracrine Effect of Adipose-Derived Stem Cells Orchestrates Competition between Different Damaged Dermal Fibroblasts to Repair UVB-Induced Skin Aging

open access: yesStem Cells International, 2020
Background. Human dermal fibroblasts (HDFs) are the primary cells in skin and are associated with UVB-induced skin photoaging. Adipose-derived stem cells (ASCs) have been proposed as a treatment for skin aging.
Feng Qin   +7 more
doaj   +1 more source

TLR4-mediated activation of the ERK pathway following UVA irradiation contributes to increased cytokine and MMP expression in senescent human dermal fibroblasts. [PDF]

open access: yesPLoS ONE, 2018
Exposure to ultraviolet (UV) radiation is a major contributing factor to premature aging (photoaging) and skin cancer. In vitro models of cellular senescence have proven to be very useful for the study of slow and progressive accumulation of damage ...
Seong-Wook Seo   +3 more
doaj   +1 more source

Impact of intraventricular haemodynamic forces misalignment on left ventricular remodelling after myocardial infarction

open access: yesESC Heart Failure, 2022
Aims Altered left ventricular (LV) haemodynamic forces (HDFs) have been associated with positive and negative remodelling after pathogenic or therapeutic events.
Domenico Filomena   +10 more
doaj   +1 more source

Big Data Technology Fusion Back Propagation Neural Network in Product Innovation Design Method

open access: yesIET Networks, Accepted Article., 2022
This research uses big data technology to combine the process of product innovation design method, which has certain significance for the formation of intelligent and systematic product innovation design method. Meanwhile, while predicting the results of all products innovative design methods, it can improve the product's predictive innovative design ...
Ren Li, Qiang Zeng
wiley   +1 more source

UV-induced senescence of human dermal fibroblasts restrained by low-stiffness matrix by inhibiting NF-κB activation

open access: yesEngineered Regeneration, 2022
As a hallmark of skin aging, senescent human dermal fibroblasts (HDFs) are known to lose the ability to divide. However, they can still interact with their cellular environment and the surrounding matrix. As the skin ages, the progressive slowing down of
Xuefeng Yao   +3 more
doaj   +1 more source

Energy-Aware Task Scheduling Using Hybrid Firefly-BAT (FFABAT) in Big Data

open access: yesCybernetics and Information Technologies, 2018
In modern times there is an increasing trend of applications for handling Big data. However, negotiating with the concepts of the Big data is an extremely difficult issue today. The MapReduce framework has been in focus recently for serious consideration.
Senthilkumar M.
doaj   +1 more source

Interphase Chromosomes in Replicative Senescence: Chromosome Positioning as a Senescence Biomarker and the Lack of Nuclear Motor-Driven Chromosome Repositioning in Senescent Cells

open access: yesFrontiers in Cell and Developmental Biology, 2021
This study demonstrates, and confirms, that chromosome territory positioning is altered in primary senescent human dermal fibroblasts (HDFs). The chromosome territory positioning pattern is very similar to that found in HDFs made quiescent either by ...
Ishita S. Mehta   +9 more
doaj   +1 more source

A distributed storage method of remote sensing data based on image blocks organization(一种基于影像块组织的遥感数据分布式存储方法)

open access: yesZhejiang Daxue xuebao. Lixue ban, 2014
云存储是解决动态增长的海量遥感数据产品存储管理难题的有效手段.针对云存储在遥感数据存储领域中存在的问题,提出了一种基于影像块组织的遥感数据分布式Key-Value存储模型,解决了分布式文件系统存储大规模影像块效率低下的问题,使遥感数据云存储具备了空间区域访问特性;结合开源分布式文件系统HDFS,实现了影像数据的分布式高效存储与空间区域检索.实验与分析表明,系统在多用户并发连接情况下可以维持较高的吞吐率,同时具备良好的可伸缩性和稳定性.
CHIZiwen(池子文)   +3 more
doaj   +1 more source

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